Conserved Protein Domain Family
M-inducer_phosp

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pfam06617: M-inducer_phosp 
M-phase inducer phosphatase
This family represents a region within eukaryotic M-phase inducer phosphatases (EC:3.1.3.48), which also contain the pfam00581 domain. These proteins are involved in the control of mitosis.
Statistics
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PSSM-Id: 399542
View PSSM: pfam06617
Aligned: 21 rows
Threshold Bit Score: 170.678
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003962921 114 LD-----------NTFERAIQQSSRIV-NQKMPIRRINSLPVQLQSCSPSLK----GRDVDAARYGifgrqpSGAmt--s 175 torafugu
7_pfamImport   1 MDspspmdpldieEKFEKAILESGKVViDNKCPIRRINSLPLRLLGSSPALK----HSQLNSLGCGifsdqhETF----- 71 
AAI66320      98 LDspspqdselphETFEKVIFESRIPPnDIKLPIRRIHSLPETLQGGSPALRrlshPLDLDLP----------KPlekip 167 tropical clawed...
XP_007666523 102 LDspsqldpqaqeEAFEKAIQESGRVIrDNKFPIRRIQSLPMRLLGSSPALKnitnARNLPPSp-------vDGPehkqa 174 platypus
XP_012395995 115 MDspspvdpqamdHVFQEAIREAGQVr-EERLPIRRFQSLPSKLLGSSPALRnitnSRDLDAPrk------gKGDvqldt 187 Tasmanian devil
NP_001274445  49 MDspspmdphmaeQTFEQAIQAASRIIrNEQFAIRRFQSMPVRLLGHSPVLRnitnSQAPDGRrk------sEAGsgaas 122 human
P48966       111 MDspspmdpqtaeRTFEQAIQAASRVIqKMQFTIK-ASVFASEAAGHSPVLQnitnSQALDSWek------dEAGyraas 183 Norway rat
EDL77098      86 LDspgpl-----------------dskeNLEISLRRINCLPQKLLGCSPALKrs-hSDSLDHDifq------------li 135 Norway rat
XP_012996227  86 LDspgpl-----------------dskeNLGNPLRRIHSLPQKLLGCSPALKrs-hSDSLDHDifq------------li 135 domestic guinea...
NP_001138685  85 LDspgpl-----------------dskeNLENPMKRINSLPQKLLGCSPALKrs-hSDSLDHDvfq------------li 134 horse
XP_003962921 176 SVCDNKENlpeEGFEFKKPTKPVSRSRVRS-FNGGPSK------------EAFSCRPSS--------------------- 221 torafugu
7_pfamImport  72 PAEGNKENvsgSGATWKKKKKKKKKKTLKE-INGGTSR------------PLRLRRPASylrmqlsspppklsikcfpas 138
AAI66320     168 AEKDNKEN---ELLLFKKP-RPFLRTRLRT-FDGCSDR------------EAFSKRPNS--------------------- 209 tropical clawed...
XP_007666523 175 SLWDNKEN---EGFVFKMPTRPTARSRPHA-VDSASRR------------DAFAQRPNS--------------------- 217 platypus
XP_012395995 188 SSGEDKEN---ETFVFKMPSRPAGHSRSAA-AEWASRR------------EAFAQRPNS--------------------- 230 Tasmanian devil
NP_001274445 123 SSGEDKEN---DGFVFKMPWKPTHPSSTHAlAEWASRR------------EAFAQRPSS--------------------- 166 human
P48966       184 SPGEDKEN---DGYIFKMPQKLPHSSSARAlAEWASRR------------EAFTQRPSS--------------------- 227 Norway rat
EDL77098     136 DQDENKEN---EAFEFKKPIRPASRGCLNA-HVHEESK------------DPFTHRQNS--------------------- 178 Norway rat
XP_012996227 136 DQDENKEN---EAFEFKKPVRPL-------------ARgclhahgceegrEFFTQRQNS--------------------- 178 domestic guinea...
NP_001138685 135 DQDENKEN------------------------------------------------------------------------ 142 horse
XP_003962921 222 ------APALMLsSPPPVtQQLDf-yDSSPSFLRRSSLTSSln-----dDDEDDGFLEILDD-HMED-DagMPMGMESLL 287 torafugu
7_pfamImport 139 clvfsfVPSLFL-PPPPKkKWRDvlsNSSPILLRRCSLTSSl------nDEEDCGFLEILDG-DDVN-D--VPPGMESLL 207
AAI66320     210 ------APTLMFfSPDKInSEME---NESPIRLRKSSLTFSlc----ndDDDDDGFMEIMDDeEIKTd---IPSGMRNLL 273 tropical clawed...
XP_007666523 218 ------APDLMFcSPERSeAEDE---AASPMCLRRCSLTSIl------vDEGDDGFMDILEQ-DLKNdDddVPFGMESLL 281 platypus
XP_012395995 231 ------APDLMCfSPGEReE------NLGPLPLRRFSMNQSsasgddasDDGDDGFMDILED-DLKN-EeeVPPGMESLI 296 Tasmanian devil
NP_001274445 167 ------APDLMClSPDRKm-EVE---ELSPLALGRFSLTPAeg-----dTEEDDGFVDILES-DLKD-DdaVPPGMESLI 229 human
P48966       228 ------APDLMClTTDGKm-DVE---EASPVA-QSSSLTPVer-----aCEEDDGFVDILES-DLKD-DdmVPAGMENLI 289 Norway rat
EDL77098     179 ------APARMLsSNESDiSESG---NFSPLFTPQSPVKATl-------SDEDDGFIDLLDGeNLKN-DeeTPSCMSSLW 241 Norway rat
XP_012996227 179 ------APARMLsSNERDsSEPG---SLVPLYLPQSPVTATl-------SDEDDGFMDLLDGeNLKN-DeeTPSCMASLW 241 domestic guinea...
NP_001138685 143 -----------LsSNERDsSEPG---NFIPLFMPQSPVTAAl-------SDEDDGFMDLLDGeNLKN-DeeTPSCMASLW 200 horse
XP_003962921 288 Taplvadgaadspvircrpr------slfrspsmpspvprpsakRPDCPADETTPIRVKRRRSLAGSq-VTTQEQNPESP 360 torafugu
7_pfamImport 208 TaplvtpkdpaqdldqdqvirsrrprglfrspsmpsnvirpilkRVERANDEETPVKNKRRKSVAGTtmTEELKENFLNI 287
AAI66320     274 Tapfvnkedksdpdliikskc----rrlfrspsmpssiirpilkRLDRPEDGETPVKSKRLKNLPQS--HSEEWPENEEP 347 tropical clawed...
XP_007666523 282 Taplvgkkedlvmhskcrr--------lfrspsmpssairpilkRLDRPQDRDTPIKTKRRKSIT----SPACEKAEEEP 349 platypus
XP_012395995 297 Saplvrkeeeseqslvmhskc----rrlfrspsmpntsirpvlkRLERPRDKDTPVKNKRRKSVTIP--TAALEENEEEP 370 Tasmanian devil
NP_001274445 230 Saplvktlekeeekdlvmysk---cqrlfrspsmpcsvirpilkRLERPQDRDTPVQNKRRRSVT----PPEEQQEAEEP 302 human
P48966       290 Saplvkkldkeeeqdlimfsk---cqrlfrspsmpcsvirpilkRLERPHDRDVPVLSKRRKSGT----PLEEQQ-LEEP 361 Norway rat
EDL77098     242 Taplvmrrptnladrcglf-------dspspcsstsscstravkRADRSHEESPRGTKRRKSSEASP--VKADVPEPTQ- 311 Norway rat
XP_012996227 242 Taplvtrratnlgtrgqh----------cdasspcspsirpvlkRPERWQEDSPRGNMKRRRSAAGA--------SPQET 303 domestic guinea...
NP_001138685 201 Taplvmrrttnlgnrckl----------fdspsmcsstarpvlkRPERSQEESPPGNTKRRKSMAGA--SPGEAASPEKP 268 horse
XP_003962921 361 RVgs--aLFQRSKSFCQT---KIET 380 torafugu
7_pfamImport 288 QMgcsmvKLARSKSFCHQ---EIER 309
AAI66320     348 KM-----KLGRSKSVCLA---TVEK 364 tropical clawed frog
XP_007666523 350 RA-----RILRSKSLCHD---EIEN 366 platypus
XP_012395995 371 KP-----RLLRSRSLCHD---EIET 387 Tasmanian devil
NP_001274445 303 KA-----RVLRSKSLCHD---EIEN 319 human
P48966       362 KA-----RVFRSKSLCH----EIES 377 Norway rat
EDL77098     312 -------LPHQSLSLTSFpkgTIEN 329 Norway rat
XP_012996227 304 PE-----ILRHSLALVPSpkgTIEN 323 domestic guinea pig
NP_001138685 269 QE-----ILHQSLSLASSpkgTIEN 288 horse
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