4EPZ


Conserved Protein Domain Family
UpxZ

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pfam06603: UpxZ 
UpxZ family of transcription anti-terminator antagonists
The UpxZ family of proteins acts to inhibit transcription of heterologous capsular polysaccharide loci in Bacteroides species by interfering with the action of the UpxY family of transcription anti-terminators. As antagonists of polysaccharide locus-specific UpxY transcription anti-terminators, the UpxZ proteins exert a hierarchical level of regulation, insuring that only one of the multiple phase-variable capsular polysaccharide loci per cell characteristic of this genus is transcribed at a time.
Statistics
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PSSM-Id: 399536
Aligned: 20 rows
Threshold Bit Score: 142.8
Threshold Setting Gi: 81316378
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4EPZ_A          10 LELQRXAHELXYLDTNGSPIYSDEFCRLNKEVLTRSDSLFSE--QSSD--IEEEGNLCLALLXGYNATIYD-NGDKERKK 84 
WP_005930978     7 QELKHLAHQLLYLGTDDTPIYADSLAKLNKEVTQKANALFTA--KAST--NEEEALLCLALLMGYNAVMYS-QSEIENRK 81  Bacteroides s...
Q5LGJ1           7 NSVSSVVKKLLEYGEDGTPVYVNELTALNQELRNLCADLLLQ--KGES--PEEEAEILVTLFKGYDTMLFNfSSENEQVI 82  Bacteroides f...
Q8A770          11 EGLLSLVRMLLPDGGSAGCVYLDDLSALQRSIHEKINDLYSQ--RGET--PEQDATLCLAILQGYNVSMYA-NPEDEERK 85  Bacteroides t...
jgi:Bache_2152   9 LELQQRAHDLMYLDIYGESVYSDDFCCLNKEVLVKSDSLFSE--KGSG--VEEEANLCLALLMGYNATIYD-NGDKGQKK 83  Bacteroides h...
EDO51767         9 LELQRMAHELMYLDTNGSPIYSDEFCRLNKEVLTRSDSLFSE--QSSD--IEEEGNLCLALLMGYNATIYD-NGDKERKK 83  Bacteroides u...
WP_005923079     9 LELQRLAHQLLFFEEDAS-LYSDDFCRQNRTVLTLSDTLYSLwnTAGSlmPEEDAEVCLALLMGYNATIYG-DSNKQEHI 86  Bacteroides s...
Q5LHA6           8 ASLQRAAHDLMYLGMDGSPIYSDDLSRRNNEVYRLTTTLYNSgvQGST--VEEQASVCLALLMGYNASFID-HGEKREHV 84  Bacteroides f...
Q5LF43           9 SALYASAHELCYLGMDGRPIYSDQFTRLNRDVFSQANALYDK--RGNS--HEEEARLCLSLLMGYNATLYN-NGDKEERI 83  Bacteroides f...
Q5L9S1           9 TALYTLAHELLYLGSDGSPIYSDHFSRLNGDVLSRANTLYPH--HGST--DEEEARLCLSLLMGYNATIYN-NGDKEVRI 83  Bacteroides f...
4EPZ_A          85 QVILDRIYNIXSQLPASLLKXRLLTWGYS 113
WP_005930978    82 QAVLDRAGKILDKISPSLLKCQLLTYCYG 110 Bacteroides salyersiae
Q5LGJ1          83 QELLDRSMTVLEKLPASVLKCQLLLECFE 111 Bacteroides fragilis NCTC 9343
Q8A770          86 QAVLTRSLSLLDVLPPSLLKQQLSAVCYG 114 Bacteroides thetaiotaomicron
jgi:Bache_2152  84 QAVLDRISEILEQLPASLLKVRLLACCYG 112 Bacteroides helcogenes P 36-108
EDO51767        84 QVILDRIYNIMSQLPASLLKMRLLTWGYs 112 Bacteroides uniformis ATCC 8492
WP_005923079    87 QQVLDCCWKVLPHLPVSLQKLRLLTYCYG 115 Bacteroides salyersiae
Q5LHA6          85 QKILDRCWDILDTLPASLLKLRLLTACYG 113 Bacteroides fragilis NCTC 9343
Q5LF43          84 QHILDRCWDVLEHLPASLLKVQLLVYCYG 112 Bacteroides fragilis NCTC 9343
Q5L9S1          84 QQILNRCWEVLDRLPASLLKVRLLTYCYG 112 Bacteroides fragilis NCTC 9343
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