3OP1


Conserved Protein Domain Family
FAD_syn

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pfam06574: FAD_syn 
FAD synthetase
This family corresponds to the N terminal domain of the bifunctional enzyme riboflavin kinase / FAD synthetase. These enzymes have both ATP:riboflavin 5'-phospho transferase and ATP:FMN-adenylyltransferase activity. They catalyze the 5'-phosphorylation of riboflavin to FMN and the adenylylation of FMN to FAD. This domain is thought to have the flavin mononucleotide (FMN) adenylyltransferase activity.
Statistics
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PSSM-Id: 399522
Aligned: 53 rows
Threshold Bit Score: 155.028
Threshold Setting Gi: 81344925
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3OP1_A  15 DIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA----RKDLLPIVVXTFNESPKIALEPyHPDLFLhILNPAERERKLKR 90 
O84095  11 LPSSNPVESVTIGFFDGCHLGHQALLSFLTKFP----SKSG----VITFSQHPEHTLS--NSPPET-ITSLEERVQLLAG 79  Chlamydia trachomatis
Q8F0P3  55 GKTIHSPCVVTLGNFDGIHLGHQALLDQVLKVS----QTTGLSSCVVTYDPNPAIVLG--KKAGMKiLMSLEDKEEWIRQ 128 Leptospira interrogans
Q9RVL9   8 SQRPDTETVIAIGSFDGVHLGHQALLAQLKARA----REYRVPSVVYTFDP-PTRVLM----QGVEfLSTLPEKLDLLRL 78  Deinococcus radiodurans
Q895J4  11 KTKYNLDIYVALGSFDGLHLGHMKLIDKAIKLA----KENNGKSMVYTFKNHPLGVIN--ENLAPKlLMDNSTKIEVLKN 84  Clostridium tetani
P57250  10 IKEINSNSVVTIGNFDGIHLGHQKLFSHIYQIG----QKYKLSTIVVLFEPQPLEFLRK-NNAPVR-ITKFREKIRRISS 83  Buchnera aphidicola s...
Q8D2Q9  13 KKQYINGCVITIGNFDGVHLGHQKIISKLKNES----LKRNLPMIVVIFEPQPKEFIN--KNSPSR-ITGLRDKIKYFKK 85  Wigglesworthia glossi...
O66535  21 LEEVPENTAITVGNFDGVHLGHRYLIENLKKKA----KSENLKTLVLTFCPHPLKVLAP-QLLPCE-LTDINEKIEIFRE 94  Aquifex aeolicus
O83858  14 CIACDRGAAISVGGFDGPHRGHAFLFDKVFAAAcapvADRARCTGLITFTHPPRKHKT--SSYEGD-LSTLRLRLRYFRA 90  Treponema pallidum
Q8A4Q4   8 SAMIPEPCVATIGFFDGVHMGHRYLIQQVKEIA----AAKGLRSALVTFPVHPRKVMNA-AYHPEL-LTTPEEKTNLLAG 81  Bacteroides thetaiota...
3OP1_A  91 EGVEELYLLDFSSQFASLTAQEFFATYIk-AXNAKIIVAGFDYTFGSDKK-TAEDLKNY---FDGEVIIVPPV--EDEKG 163
O84095  80 CGIDYLAVLPFNQEIANQEAEPFIQS-IykTLRPSRIVLGYDSRLGKGGLgTAQTLRPFaasLGISLEEVPPL--QIEGT 156 Chlamydia trachomatis
Q8F0P3 129 KGIDFLVVLPFNTELAEMNAELFLEEILlkQLKAKNIIIGFNHCFGKQRRgNYELLKEYsekLKYSVKKVDPV--YLNDT 206 Leptospira interrogans
Q9RVL9  79 YGIDETIAVPFTPEFAARPKEAFLAD-Lr-AMKPRAVVVGEDFYFGKGRAgSTADLREVc----ADVVSLPMH--QLGGD 150 Deinococcus radiodurans
Q895J4  85 KGVDILRFICFDKNFMEISPEDFILN-IikQYNIKGIVVGFNFRFGHKNSgDVELLKELskkYDFQLFIVGPV--EYNDE 161 Clostridium tetani
P57250  84 YNFDSILCVKFNKSFQSLSAKDFIINILinKLHLKFIVIGNDFRFGFQRNgNINLLKKLgykYQFNVIKIRPL--YKNNI 161 Buchnera aphidicola s...
Q8D2Q9  86 MGIKQVLCINFNKNFLMLNAKDFIKNFLikSLNMKCIIIGKDFRFGYKAYgDVKLLKNSgkkLGFNVLEVKTL--EIDSE 163 Wigglesworthia glossi...
O66535  95 LGVDYLCFIRFDKEFAKIRAREFLEKIIyeKLKCRYLLVGYDWRYGYRREgEIELAKEVgseLGFEVEEAKPF--KIKGH 172 Aquifex aeolicus
O83858  91 RGFDFVVLIDFSKDFARIPGGVFFNTLLr-AVRVCYLAVGVDFRCGHGLDtGVRELRRLgdaHSFVCDAVGHY--TLEGV 167 Treponema pallidum
Q8A4Q4  82 TGVDYCLMLDFTPDISRLTAKEFMTQILkeRFQVKYLVIGYDHRFGHNRSeGFDDYVRYgqaIGIEVIRAQAYtdDIQID 161 Bacteroides thetaiota...
3OP1_A 164 KISSTR 169
O84095 157 IVSSRK 162 Chlamydia trachomatis
Q8F0P3 207 KLSSSY 212 Leptospira interrogans
Q9RVL9 151 DIKSTR 156 Deinococcus radiodurans
Q895J4 162 VVSSSR 167 Clostridium tetani
P57250 162 KISSTN 167 Buchnera aphidicola str. APS (Acyrthosiphon pisum)
Q8D2Q9 164 KISSTA 169 Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
O66535 173 IVSSTL 178 Aquifex aeolicus
O83858 168 RVSSSA 173 Treponema pallidum
Q8A4Q4 162 TIQSAP 167 Bacteroides thetaiotaomicron
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