Conserved Protein Domain Family
Chon_Sulph_att

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pfam06566: Chon_Sulph_att 
Chondroitin sulphate attachment domain
This family represents the chondroitin sulphate attachment domain of vertebrate neural transmembrane proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synaptogenesis. This domain contains several potential sites of chondroitin sulphate attachment, as well as potential sites of N-linked glycosylation.
Statistics
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PSSM-Id: 368978
View PSSM: pfam06566
Aligned: 7 rows
Threshold Bit Score: 167.805
Threshold Setting Gi: 76364133
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EHB12567       2 REMGSAAEAEELAKS-GLAWEPHANDTr-eVGLPAAGDDdqlwrapgGDLGPVPPGa-------eFGPEEAPKAS----A 68  naked mole-rat
Q9DF69        55 PPGGGPATADPTVGCmGCSGEGAASSV---PPVPDAAQD--------PRLGVTGPTdgdggvvalGSPEEVGSGEqptrA 123 chicken
Q0VCM1        34 PEAGSAVEADTPVKS-VPAWEPRANDTrekAGPPAAGKDetsriapgGEQALVGPG---------VGAEEALEAS----A 99  cattle
XP_023403887  83 RDASSAVEAEGPVKS-VLAWEPRANDTrdgAAPSGTGEDetawtapaDEQAAAGPR---------VGPEEALEAS----A 148 African savanna...
XP_003794589  34 REAGSALEAEEQVKS-GLEWEPRANDTq-eTYLPAAEENetswtapgGDLAIV-------------DPEEVLQAS----A 94  small-eared galago
Q9ERQ6        34 REAGSAIEAEELVRS-GLAWESRANDTreeAGLPAAGEDetswtergSELAAVGPG---------VGPEETLEAS----A 99  Norway rat
XP_008258776  34 REAGSAVEAKE-LKT-GLAQESRANATqdeAGPPAAGKE--------PELGAA-------------TPEETLEAS----A 86  rabbit
EHB12567      69 AVTRTVWLEAEDAGLGGVTAEAGS-GDTQALPA------TLLAPDDTLEQSTipPSPPEATEAGAPPLPTTAHQPS---P 138 naked mole-rat
Q9DF69       124 GVGPTEGLTPRPPGLPSPGLGLSSpGPNLGLPSldlpnpNLGLPDPNLGLPN--PSLGLPSPGPTPDRPIPNPNPSldlP 201 chicken
Q0VCM1       100 AVTSTAWLEAESPGLGGVTAEAGS-GDTQALPA------TLPTPDEALGTSStsAATFEATEASEPPSPAPGDKPS---P 169 cattle
XP_023403887 149 AVTGASWLETDSPGLGAVTTEVGS-GDAQALPA------TLPAPDEALGQSSvpPATPEAIR---PPSSTPGNKPS---P 215 African savanna...
XP_003794589  95 AVTSTTWLEADSPGLGGVTAEAGS-GDAQALPA------TLQAPDEALGHSLmlPATPEATEASEPLSLIHGDKLS---P 164 small-eared galago
Q9ERQ6       100 AVTGTAWLEADGTGLGGVTAEAGS-GDAQTLPA------TLQAPDEALGSSTmpPAIPEATEASGPPSPTLRDKPS---L 169 Norway rat
XP_008258776  87 AVTGTAWLEVDSPGLGGGTIDMGS-GDAQAIPA------TLQAPQEALGQSAmpPTTPETPEVSGPPSPTPRDKLS---P 156 rabbit
EHB12567     139 RPKLPKESPmevwlNLGSSTPDPQEPGPTdPIPGTLE---------------PQPAS----------------------- 180 naked mole-rat
Q9DF69       202 DPGLAIQTP-----NLGLSNPNIPLPSPS-PGPGTEPdllpvaedsevsmelPQPSSspapaqrargrtdrtwlgapepi 275 chicken
Q0VCM1       170 GPELPKESPmevwlNLGGSTPDPHGPEPTyPFQGTLE---------------PHPAS----------------------- 211 cattle
XP_023403887 216 GPELPKESSleiwlNLGGSTPGPHGLEPTyPFQGTLE---------------PQPAS----------------------- 257 African savanna...
XP_003794589 165 ASEFPKESPlevwlNLGGSTPDPQGPEPTyPFQGTLD---------------PQPAS----------------------- 206 small-eared galago
Q9ERQ6       170 VPELPKEIPlevwlNLGGSTPDPQRPEPTfPLQGTLE---------------TQPAS----------------------- 211 Norway rat
XP_008258776 157 DPELPKESPlevwlNLGGSTPDPQGSEPTyPFQGTQE---------------PQPAS----------------------- 198 rabbit
EHB12567     181 ----------EIIDIDYFEGLDGdGRDADLGSfpGSPGTSEHHPd--pEGETPSWSLLDLYDDFTPFDESDFYPTTSFY- 247 naked mole-rat
Q9DF69       276 saapgtaeppEIIDVDYYDVFDG-GHGPGGGH--GAGGAAQREP----GGAATPWGLHELYDDFTPFDEADFYPTTSFYa 348 chicken
Q0VCM1       212 ----------DIIDIDYFEGLDGeGRGADLGSfpGSPGTSEHHPd--pGGETPSWSLLDLYDDFTPFDESDFYPTTSFY- 278 cattle
XP_023403887 258 ----------DIIDIDYFEGLDGeGRGADLGSfpGSLGTSEHHPdtdtGGETPSWSLLDLYDDFTPFDESDFYPTTSFY- 326 African savanna...
XP_003794589 207 ----------DIIDIDYFEGLDGeGRGADLGSfpGSPGTSENQPd--tEGETPSWSLLDLYDDFTPFDESDFYPTTSFY- 273 small-eared galago
Q9ERQ6       212 ----------DIIDIDYFEGLDSeGRGTDMGRfpGSPGTSENHPd--tEGETPSWSLLDLYDDFTPFDESDFYPTTSFY- 278 Norway rat
XP_008258776 199 ----------DIIDIDYFEGLDGeGRGADLGSfpGSPGTSENHPd--tDGEAPSWSLLDLYDDFTPFDESDFYPTTSFY- 265 rabbit
EHB12567     248 ---DDLEE 252 naked mole-rat
Q9DF69       349 egdDDAEE 356 chicken
Q0VCM1       279 ---DDLDE 283 cattle
XP_023403887 327 ---DDLDE 331 African savanna elephant
XP_003794589 274 ---DDLDE 278 small-eared galago
Q9ERQ6       279 ---DDLEE 283 Norway rat
XP_008258776 266 ---DDLEE 270 rabbit
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