Conserved Protein Domain Family
ABC_trans_CmpB

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pfam06541: ABC_trans_CmpB 
Putative ABC-transporter type IV
CmpB is a family of membrane proteins that are likely to be part of a two-component type IV ABC-transporter system. Families can transport multiple drugs including ethidium and fluoroquinolones. UniProtKB:Q83XH0 is a member of TCDB family 3.A.1.121.4.
Statistics
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PSSM-Id: 399505
Aligned: 387 rows
Threshold Bit Score: 62.0875
Threshold Setting Gi: 524401475
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Elen_1444   157 IYFCVFSVVGHWME-AA--YCT-----LiRFGMipgtydpnsqiwsdwLY-PFI-VYGF---GAVACVLllypVknfLek 223 Eggerthella ...
CDB52348         29 lagLVYAHIGYWVE-NL--FRLvskgvLdSRNQ---------------Ll-PFLfCYTI---AMWAMYL----AlgtTnh 82  Clostridium ...
CDA67948         10 LMAVLVSFLGFVVE-DG--WLAltkgyIdNRN----------------MHlPFLfGYGI---AMVGLYlilgtpatmilp 67  Clostridium ...
CDF06708         25 vMLTLVSFLGFLIE-NT--WIVltegfVdNRN----------------MNaPFLiGYGV---IVLLIYrfmgtpeqltgi 82  Firmicutes b...
CDE81187         14 iMVAVISFLGFSLE-NL--WLSltkgfIdNRN----------------MNaPFLmGYGL---LVVGMYlllgtpenmala 71  Ruminococcus...
CDC78857         25 WVFTVFSILGWVFD-TVadSLTng--rMvNRGL---------------LVgPFCpTYGIlcaGAYILNvflc-------- 78  Clostridium ...
jcvi:TREPR_2746  14 FAFFFFSFSGWVGE-TImeSLVrk-rfV-SKGF---------------FKgPWVpVHGV---GGFAVYA----A---Gfp 65  Treponema pr...
WP_009243621    366 FLFHAASCFGWIMEmLI--HLmrd-gtVaDIHL---------------LFgPWLpLYGI---YGIIILK----A---Skr 417 [Ruminococcu...
CBL25385        343 FLFHAFSIFGWLLEiIS--ELlsc-gtLeNVTL---------------KTlPWLpLYGI---CGLLILL----L---Lkk 394 [Ruminococcu...
CCZ67912        366 sLFFLFSILGWILEtLS--YLtme-gvFlNRSI---------------LLgPWIpLYGI---CGVLSVT----M---Lhr 417 [Ruminococcu...
jgi:Elen_1444   224 rirsr------------vvpllisFVVNA----LVCTTIELVMGLMVNQPGpDGKlpLWDYSDMFCN----FMGQVCLQN 283 Eggerthella ...
CDB52348         83 prffshrvlegntrrdkilariyyFTVVF----LFVFFGEIVVGSIFEQVS-GIS--LWDYSGIPLH----VTKYTSIPT 151 Clostridium ...
CDA67948         68 fq---------ikkketfvrfiiyFVLVM----LAVSVGEIILGTLVEKVC-HFC--WWDYTVIPLH----ITRYTSVPT 127 Clostridium ...
CDF06708         83 lq--------fargwtrhgrislyFLTSF----FVVCSVEILTGYVVEKVC-SLY--YWSYEALPLH----ITRYTSLPT 143 Firmicutes b...
CDE81187         72 em--------vpvdrskgekffvyFLCAF----AVVTVGELILGHLMEKIC-GIQ--YWNYNWIPLH----ITQYTSIPT 132 Ruminococcus...
CDC78857         79 ---------------------kdvFFVQLglytLLCTVVILCMNAFLDKAF-NIK--IWDFSGDYFN----YKGYISLPG 130 Clostridium ...
jcvi:TREPR_2746  66 lka----------------rpillFITST----LLCTAVEYLAALLLEKVF-NKK--CWDYDTYPFTwwchYKKRIALTT 122 Treponema pr...
WP_009243621    418 llk----------------kpvfvFFLNF----IVFSFLQYIFSFTVELFS-GYK--LWDFSEFFLN----INGRIYLGG 470 [Ruminococcu...
CBL25385        395 yik----------------kpatmFIINF----VVYTALDYLVQLLLDFGF-GIE--LPKYHSYLTF----MNGEAYLGD 447 [Ruminococcu...
CCZ67912        418 fak----------------npilaFCMNG----LLYSVIGYLSDFTVQMIW-HAD--LHKISQYFCP----SLLPPFFAD 470 [Ruminococcu...
jgi:Elen_1444   284 AIAFGVVATLMTWV----IYPALEQLLSKVPRDGMNIAFIAVTVGFCI 327 Eggerthella lenta DSM 2243
CDB52348        152 CTAMSLGVAVIMGNffegLMKKIQR----IPYRTTVQLDYVLGTLILV 195 Clostridium sp. CAG:217
CDA67948        128 SLGFALIITTFMDKfcipILDHLAA----IPAERATVLAWILGVSLSV 171 Clostridium sp. CAG:510
CDF06708        144 SVSFAFLIVFFMGIvytpAMKWITR----VDNRVLRVVSLLLVLLLVL 187 Firmicutes bacterium CAG:95
CDE81187        133 SIGFAAIITSFMGAcfdpIMSVITM----IPAQEAKSASIILMLIMST 176 Ruminococcus sp. CAG:353
CDC78857        131 VVLGGFILSVITSQmdgiIVMLVKE----IPPLINFIVMISVLTVMLL 174 Clostridium sp. CAG:964
jcvi:TREPR_2746 123 SLFFGLVALVLVYF----YWDLAMDIARFIGPQALFIIDLVLVTVFLV 166 Treponema primitia ZAS-2
WP_009243621    471 SAAFALLGCAFIYY----LAPNWTNYFSKLSKKTQTVFCVILNSLFIT 514 [Ruminococcus] torques
CBL25385        448 GAVFALLGCAFFYY----FAPRWNSLFLKLKKWMRISICILLTAIFVF 491 [Ruminococcus] torques L2-14
CCZ67912        471 TMFLGLIGCACQYF----ITPKWKQITRKIPLWFLLCVCVLLGMLMLL 514 [Ruminococcus] gnavus CAG:126
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