6AGF,6J8G


Conserved Protein Domain Family
Na_trans_assoc

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pfam06512: Na_trans_assoc 
Sodium ion transport-associated
Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.
Statistics
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PSSM-Id: 399489
View PSSM: pfam06512
Aligned: 69 rows
Threshold Bit Score: 82.0231
Threshold Setting Gi: 241153636
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6AGF_A        859 DGEMNNLQIAIGRIKLGIGFAKAFLLGLLHGKIlSPKDIMLSLGEADGAgeageagetapedekkeppeedlkKDNHILN 938 
XP_005317491  815 eARKTKVQLALDRFGRAFSFVIHTLEHFCCKRC-KRHNLPKLKEMTADSdae-------------------skDIIPLAA 874  thirteen-line...
XP_002407119 1012 sGDTKKLQEAIDRFHRASRWIKSNSMKVV-------------------Ktfr-------------------rkPRNQIGD 1053 black-legged ...
EFA11577     1022 DNDTNKIAEAFDRIGRFIRWIKGNVLHIA-------------------Klvr-------------------fkLTNQISD 1063 red flour beetle
NP_001138205 1035 DNDTNKIAEAFNRIGRFKSWVKRNIADCF-------------------Klir-------------------nkLTNQISD 1076 fruit fly
XP_002427248  967 DNDTNKIAEAFNRISRFNAWVKRSILNFL-------------------Kmlr-------------------akISNQIGD 1008 human body louse
EFN61422     1033 DNDTNKIAEAIDRIARFINWIKRNILNIA-------------------Klmr-------------------akFTNQISD 1074 Florida carpe...
XP_016836968 1021 DNDTNKITEAIDRISRFIAWTKRNILNLL-------------------Kmlr-------------------akFTNQISD 1062 jewel wasp
XP_318122    1020 DNETNKIAEAFNRISRFSNWIKMNLANAL-------------------Kfvk-------------------nkLTSQIAS 1061 Anopheles gam...
ABP96886      480 DQDTNKIAEAFNRISRFIDWIKRNVADFL-------------------Kllk-------------------nkLTNQIAI 521  domestic silk...
6AGF_A        939 H----------MGLADGPPSSleld--------------------hlnFINN--PYLTIQVPIA---------------- 970 
XP_005317491  875 DmkrgseaqeeFGVLNSAQKT---------------------------FSLG--YDRSWLAPLA---------------- 909  thirteen-line...
XP_002407119 1054 Q------------TTDIRGSNgaageelegdpagagevvlldgrvpmrDKKPphNNADLEVVVGdgleiaiqgdgkavkm 1121 black-legged ...
EFA11577     1064 Qps-------dVRcdggldisg------------------deiladgiIKKS--PKDRLEVTIGtgmdltvhgdpk---- 1112 red flour beetle
NP_001138205 1077 Qpsehgdnelelg-----------------------hdeiladglikkGIKEq-TQLEVA--IGdgmeftihgdmknnkp 1130 fruit fly
XP_002427248 1009 Htglpdgrdrdtdle--------------------lgdeilvdgmvfrDKKNskDQLEVA--IGdgmeftihgdfkeklr 1066 human body louse
EFN61422     1075 Qapge--gpsnSWKED--GIDrdgdldladg--------eldayrdkkSAKEl-NQLEVA--IGegmeftihgdlknklk 1139 Florida carpe...
XP_016836968 1063 Qa----------pDG----IDrdmnmdlaeg--------eldayrdkkSVKElnNQFEVA--IGdgmeftihgdlknkmr 1118 jewel wasp
XP_318122    1062 Vqp--------tgKG----VCpcissehgeneleltpddiladgllkkGIKEh-NQLEVA--IGdgmeftihgdlknkak 1126 Anopheles gam...
ABP96886      522 Hapervdnelel-------------------------gtdlddavlykDKKLk-DQVEVA--IGdgmeftipgdnkykk- 572  domestic silk...
6AGF_A        971 ------------------------SEESDLEmPT---------EEETDTFse------------------------pEDS 993 
XP_005317491  910 ------------------------EEENDVEyFD---------KDDASSImh------------------------sEAE 932  thirteen-line...
XP_002407119 1122 klknnskpvmnsvwvgpmiepknkPPE----------------KDNKEKVrtspfyvhierhnntslylgngggggeEEK 1185 black-legged ...
EFA11577     1113 -------------rgknninksktIGNSILEhGMyig----hlDEDEISNksygshknrfkee--shkgsvdmlddhEEK 1173 red flour beetle
NP_001138205 1131 k-------kskylnnatmignsinHQDNRLE-HElnhrglslqDDDTASInsygshknrpfkd--eshkgsaetmegEEK 1200 fruit fly
XP_002427248 1067 rs----kmalnnknnvignsyaglNSDNRFE-SDyit----hnEEDTYSNisygshrkriykd--eshkgsidtfeeDEK 1135 human body louse
EFN61422     1140 --------nklcmnntkviansinHHDYRLD-NDyin----qnEDDTISNksygshknrafkd--eshkgsmdslngEEK 1204 Florida carpe...
XP_016836968 1119 t-------slclnntkalvnsinhHRDFRLD-HDymn----hnEDDTISNksygshknrsfkd--eshkgsldsldgEEK 1184 jewel wasp
XP_318122    1127 k------nkqimnnskvignsisnHQDNKLD-HElnhrgvslqDDDTASIksygshknrpfkd--eshkgsaetmegEEK 1197 Anopheles gam...
ABP96886      573 ----------gkilmnniyrithyHRDNRLD-CElnhhgypiqDDDTISQksygshkirsfkd--eshkgsadtidgEEK 639  domestic silk...
6AGF_A        994 KKP-PQPLY---------------------------------DGNSSVCSTADYKPPEEDPEEQAEENPEGEQ------- 1032
XP_005317491  933 RQAyDLHQEkpaipgdqsveidvfpeeevylavqnprkksdaISIPSECSTIDLQEA---FGYLYRIVPQQKQ------- 1002 thirteen-line...
XP_002407119 1186 KD------------------------------------------ASKEDLDA------KEGEDPPAEEAANPDtedvdtd 1217 black-legged ...
EFA11577     1174 RD------------------------------------------ASKEELGIG----EEETEDDRFDLEKPLTdivivgn 1207 red flour beetle
NP_001138205 1201 RD------------------------------------------ASKEDLGLD-----EELDEEGECEEGPLDgdiiiha 1233 fruit fly
XP_002427248 1136 GD------------------------------------------MSKEE---------DEEMDEEEEGESIPEidviida 1164 human body louse
EFN61422     1205 KD------------------------------------------ASKEDLEQE----GEDLEDEGEEGEE-VDidiiqae 1237 Florida carpe...
XP_016836968 1185 KD------------------------------------------ASKEDLEDDLDDEGEDEDEEEEEVEE-IPcriikqd 1221 jewel wasp
XP_318122    1198 RD------------------------------------------ASKEDLGID-----EELDDEGEGDEGPLDgeliiha 1230 Anopheles gam...
ABP96886      640 KD------------------------------------------ASKEELGLE-----EELIEEDE--EGKLDgtlgktd 670  domestic silk...
6AGF_A       1033 --------------PEECFTEACVQRW-PCLYVDISQGRGKKWWTLRRACFK 1069
XP_005317491 1003 --------------PERCLPKGLHCFF-PCCRKDRRKSLWVIWWNLRKTCYQ 1039 thirteen-lined ground squirrel
XP_002407119 1218 kletatsdviipelPADCCPDCCYTRFaACCCYDESKPLWLKYKIVRTKVYa 1269 black-legged tick
EFA11577     1208 a-----ddiiiddyAADCFPDSCYKKF-PFLAGDEDSPFWQGWGNLRSKTYR 1253 red flour beetle
NP_001138205 1234 h-----dedildeyPADCCPDSYYKKF-PILAGDDDSPFWQGWGNLRLKTFQ 1279 fruit fly
XP_002427248 1165 nm----edvmlqdyPSDCCPDHCYKRF-PFLAGDDDAPFWQGWSNLRLKTFQ 1211 human body louse
EFN61422     1238 e------dpiqdnyPSDCCPENCYKKF-PFLAGDDDAPFWQGWANLRLKTFR 1282 Florida carpenter ant
XP_016836968 1222 e------eldgensPSDCCPDNCYQRF-PFLAGDDDAPFWQGWATLRLKTFQ 1266 jewel wasp
XP_318122    1231 e-----edeviedsPADCCPDNCYKKF-PVLAGDDDAPFWQGWGNLRLKTFQ 1276 Anopheles gambiae str. PEST
ABP96886      671 ikv-gadedvvddtPADCCPEQCYQKF-PFLAGDDDSPFWQGWGTLRLKTFK 720  domestic silkworm
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