6AGF,6J8G


Conserved Protein Domain Family
Na_trans_assoc

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pfam06512: Na_trans_assoc 
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Sodium ion transport-associated
Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.
Statistics
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PSSM-Id: 428983
Aligned: 67 rows
Threshold Bit Score: 83.5474
Threshold Setting Gi: 241153636
Created: 27-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6AGF_A         859 DGEMNNLQIAIGRIKLGIGFAKAFLLGLLHGKIlSPKdimlslgeadgageageageTAPEDEKKEPPeedlkKDNHILN 938  human
XP_005317491   815 EARKTKVQLALDRFGRAFSFVIHTLEHFCCKRC-KRHn-------------------LPKLKEMTADSdaeskDIIPLAA 874  thirteen-lin...
XP_002407119  1012 SGDTKKLQEAIDRFHRASRWIKSNSMKVV--------------------------------------KtfrrkPRNQIGD 1053 black-legged...
EFA11577      1022 DNDTNKIAEAFDRIGRFIRWIKGNVLHIA--------------------------------------KlvrfkLTNQISD 1063 red flour be...
EFN61422      1033 DNDTNKIAEAIDRIARFINWIKRNILNIA--------------------------------------KlmrakFTNQISD 1074 Florida carp...
XP_016836968  1021 DNDTNKITEAIDRISRFIAWTKRNILNLL--------------------------------------KmlrakFTNQISD 1062 jewel wasp
XP_002427248   967 DNDTNKIAEAFNRISRFNAWVKRSILNFL--------------------------------------KmlrakISNQIGD 1008 human body l...
ABP96886       480 DQDTNKIAEAFNRISRFIDWIKRNVADFL--------------------------------------KllknkLTNQIAI 521  domestic sil...
NP_001138205  1035 DNDTNKIAEAFNRIGRFKSWVKRNIADCF--------------------------------------KlirnkLTNQISD 1076 fruit fly
24_pfamImport    1 DNETNKIAEAFNRISRFSNWIKMNLANAL--------------------------------------KfvknkLTSQIAS 42  
6AGF_A         939 Hm----------gLADGppSSLEldh----------------------lnFINN--PYLTIQVPIA-------------- 970  human
XP_005317491   875 DmkrgseaqeefgVLNS--AQKT---------------------------FSLG--YDRSWLAPLA-------------- 909  thirteen-lin...
XP_002407119  1054 Q------------TTDI--RGSNgaageelegdpagagevvlldgrvpmrDKKPphNNADLEVVVGdgleiaiqgdgkav 1119 black-legged...
EFA11577      1064 Qpsdvrcdggld---------------------------isgdeiladgiIKKS--PKDRLEVTIGtgmdltvhgdpk-- 1112 red flour be...
EFN61422      1075 Qapgeg--psnswKED----GIDrdgdldladg--------eldayrdkkSAKEl-NQLEVA--IGegmeftihgdlknk 1137 Florida carp...
XP_016836968  1063 Qa----------pDG------IDrdmnmdlaeg--------eldayrdkkSVKElnNQFEVA--IGdgmeftihgdlknk 1116 jewel wasp
XP_002427248  1009 Htglpdgrdrdtdle----------------------lgdeilvdgmvfrDKKNskDQLEVA--IGdgmeftihgdfkek 1064 human body l...
ABP96886       522 Hapervdnelel---------------------------gtdlddavlykDKKLk-DQVEVA--IGdgmeftipgdnkyk 571  domestic sil...
NP_001138205  1077 Qpsehgdnelelg-------------------------hdeiladglikkGIKEq-TQLEVA--IGdgmeftihgdmknn 1128 fruit fly
24_pfamImport   43 Vqp--------tgKG------VCpcissehgeneleltpddiladgllkkGIKEh-NQLEVA--IGdgmeftihgdlknk 105 
6AGF_A         971 --------------------------SEESDLEmPT---------EEETDTFse------------------------pE 991  human
XP_005317491   910 --------------------------EEENDVEyFD---------KDDASSImh------------------------sE 930  thirteen-lin...
XP_002407119  1120 kmklknnskpvmnsvwvgpmiepknkPPE----------------KDNKEKVrtspfyvhierhnntslylgngggggeE 1183 black-legged...
EFA11577      1113 ---------------rgknninksktIGNSILEhGMyig----hlDEDEISNksygshknrfkee--shkgsvdmlddhE 1171 red flour be...
EFN61422      1138 lk--------nklcmnntkviansinHHDYRLD-NDyin----qnEDDTISNksygshknrafkd--eshkgsmdslngE 1202 Florida carp...
XP_016836968  1117 mrt-------slclnntkalvnsinhHRDFRLD-HDymn----hnEDDTISNksygshknrsfkd--eshkgsldsldgE 1182 jewel wasp
XP_002427248  1065 lrrs----kmalnnknnvignsyaglNSDNRFE-SDyit----hnEEDTYSNisygshrkriykd--eshkgsidtfeeD 1133 human body l...
ABP96886       572 k-----------gkilmnniyrithyHRDNRLD-CElnhhgypiqDDDTISQksygshkirsfkd--eshkgsadtidgE 637  domestic sil...
NP_001138205  1129 kpk-------kskylnnatmignsinHQDNRLE-HElnhrglslqDDDTASInsygshknrpfkd--eshkgsaetmegE 1198 fruit fly
24_pfamImport  106 akk------nkqimnnskvignsisnHQDNKLD-HElnhrgvslqDDDTASIksygshknrpfkd--eshkgsaetmegE 176 
6AGF_A         992 DSKKP-PQPL-------------------------------Y--DGNSSVCSTADYKPPEEDPEEQAEENPEGEQ----- 1032 human
XP_005317491   931 AERQAyDLHQekpaipgdqsveidvfpeeevylavqnprkkSdaISIPSECSTIDLQEA---FGYLYRIVPQQKQ----- 1002 thirteen-lin...
XP_002407119  1184 EKKD------------------------------------------ASKEDLDA------KEGEDPPAEEAANPDtedvd 1215 black-legged...
EFA11577      1172 EKRD------------------------------------------ASKEELGIG----EEETEDDRFDLEKPLTdiviv 1205 red flour be...
EFN61422      1203 EKKD------------------------------------------ASKEDLEQE----GEDLEDEGEEGEE-VDidiiq 1235 Florida carp...
XP_016836968  1183 EKKD------------------------------------------ASKEDLEDDLDDEGEDEDEEEEEVEE-IPcriik 1219 jewel wasp
XP_002427248  1134 EKGD------------------------------------------MSKEE---------DEEMDEEEEGESIPEidvii 1162 human body l...
ABP96886       638 EKKD------------------------------------------ASKEELGLE-----EELIEEDE--EGKLDgtlgk 668  domestic sil...
NP_001138205  1199 EKRD------------------------------------------ASKEDLGLD-----EELDEEGECEEGPLDgdiii 1231 fruit fly
24_pfamImport  177 EKRD------------------------------------------ASKEDLGID-----EELDDEGEGDEGPLDgelii 209 
6AGF_A        1033 ----------------PEECFTEACVQRW-PCLYVDISQGRGKKWWTLRRACFK 1069 human
XP_005317491  1003 ----------------PERCLPKGLHCFF-PCCRKDRRKSLWVIWWNLRKTCYQ 1039 thirteen-lined ground squirrel
XP_002407119  1216 tdkletatsdviipelPADCCPDCCYTRFaACCCYDESKPLWLKYKIVRTKVYA 1269 black-legged tick
EFA11577      1206 gna-----ddiiiddyAADCFPDSCYKKF-PFLAGDEDSPFWQGWGNLRSKTYR 1253 red flour beetle
EFN61422      1236 aee------dpiqdnyPSDCCPENCYKKF-PFLAGDDDAPFWQGWANLRLKTFR 1282 Florida carpenter ant
XP_016836968  1220 qde------eldgensPSDCCPDNCYQRF-PFLAGDDDAPFWQGWATLRLKTFQ 1266 jewel wasp
XP_002427248  1163 danm----edvmlqdyPSDCCPDHCYKRF-PFLAGDDDAPFWQGWSNLRLKTFQ 1211 human body louse
ABP96886       669 tdikv-gadedvvddtPADCCPEQCYQKF-PFLAGDDDSPFWQGWGTLRLKTFK 720  domestic silkworm
NP_001138205  1232 hah-----dedildeyPADCCPDSYYKKF-PILAGDDDSPFWQGWGNLRLKTFQ 1279 fruit fly
24_pfamImport  210 hae-----edeviedsPADCCPDNCYKKF-PVLAGDDDAPFWQGWGNLRLKTFQ 257 
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