1GXL


Conserved Protein Domain Family
SMC_hinge

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pfam06470: SMC_hinge 
SMC proteins Flexible Hinge Domain
This family represents the hinge region of the SMC (Structural Maintenance of Chromosomes) family of proteins. The hinge region is responsible for formation of the DNA interacting dimer. It is also possible that the precise structure of it is an essential determinant of the specificity of the DNA-protein interaction.
Statistics
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PSSM-Id: 399464
View PSSM: pfam06470
Aligned: 98 rows
Threshold Bit Score: 39.1656
Threshold Setting Gi: 81760300
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GXL_A         41 FPgLVDVVSNLIEVDEKYSLAVSVLLGGTAQNIVVRNVDTAKAIVEFLKQNEAGRVTILPL----DL----IDGsfNRIS 112 
Q2S457        518 lfdDLYTVADVLGCDDDVRVALDAALGALASCVVVPTVDDARAAVARLRDAEKGQTSFLVL----DR----LPD--APPS 587  Salinibacter ...
Q3ATI3        532 NNsTSRCLADMIEVDERYRAALGSALGDHLNCYLCPTLSDAHHSIALLQKAQKGKLLFLVQ----EL----AAS--ASLP 601  Chlorobium ch...
WP_012466887  519 SEaDQGCLADMISLDPAYRKAVHAALGEALSYYVCRSITEAKQSMQQLRLSKKGKLHFLVL----DH----IAR--ISDN 588  Chlorobium li...
WP_012038047  505 LPgIRGLLAEHVHVQPGYEAAVAAALGSLADAVLAETHDDAVAALRRAVDDDLGRVEVVVA----GS----ADA--QLAV 574  Clavibacter m...
Q8NNW5        501 VV-DYPQLATLIRPQRNVDKALAAALGAHAEALAGEAAEGLVE--KLIDAG-VARTIIVDG----TQ----AGG--AWRL 566  Corynebacteri...
WP_009937962  512 GAgLFGSIAQLVKVLSGYEAALAAALGPAADALAVDGLTAAGSAVSALKQADGGRAVLVLS----DW----PAP--QAPQ 581  Mycobacterium...
Q0S2D5        509 QHgIRGPIGGLITVEKGYEGAVAAAMGPAADAVVAESLDAARSAVGALKETDSGRASLFIG-----------SD--HVAR 575  Rhodococcus j...
EAP97711      512 GHgIVGTVASLLQVTGGHEGAVAAALGWASEALAVGSAQQAARAVDHLRQDDQGQATLLVG----DT----ARA--SNPS 581  Janibacter sp...
Q82JU6        511 LGgLLGPAAELLSVTPGYEVPLAAAFGVAADAIAVSTPASAAEAIRLLRKQDAGRAALLLGgapdDVpapePEH--ARRP 588  Streptomyces ...
1GXL_A        113 GLENERG-------FVGYAVDLVKFPSD-LEVLGGFLFGNSVVVETLDDAIRM 157 
Q2S457        588 VSAPE---------GAVPLRDVVRTTDPaYAPLADTLLRDCFLVDTLAAAEAL 631  Salinibacter ruber DSM 13855
Q3ATI3        602 TLPTIE--------GAEPLANLVSVPPA-WQHALRLLLGTTFVVANAEQAEAL 645  Chlorobium chlorochromatii CaD3
WP_012466887  589 ETPVRE--------GGRRMMDIIGYPEA-LSAALNNLLFRYYLVDTLDTAENM 632  Chlorobium limicola
WP_012038047  575 PSSD----------GPVAAASVVEAPDG-----VRRILADVVFVDGLAEAVAL 612  Clavibacter michiganensis
Q8NNW5        567 DANIPA--------GASWLLDHVDLDPA-IAGPVNRLLADVVLVDDPSLGRQA 610  Corynebacterium glutamicum
WP_009937962  582 SASGEMLp-----sGAQWALDLVESPPQlVGAMI-AMLSGVAVVNDLTEAMGL 628  Mycobacterium tuberculosis
Q0S2D5        576 DGGHLDS-------GARWAVDVIDCPAE-LRTGLAALLGGVVVVDSLDDAVET 620  Rhodococcus jostii RHA1
EAP97711      582 TWPDLDG-------SGVWARDVVSAPAD-VLPAVEQLLDRVALVATTEHALAL 626  Janibacter sp. HTCC2649
Q82JU6        589 GAAHTDVppaehrgGPPYAADLVRGPAE-LMPAVRRLLRGIVVVGTLEDAEDL 640  Streptomyces avermitilis
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