2FB2


Conserved Protein Domain Family
Mob_synth_C

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pfam06463: Mob_synth_C 
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Molybdenum Cofactor Synthesis C
This region contains two iron-sulphur (3Fe-4S) binding sites. Mutations in this region of human MOCS1 cause MOCOD (Molybdenum Co-Factor Deficiency) type A.
Statistics
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PSSM-Id: 399458
Aligned: 52 rows
Threshold Bit Score: 105.372
Threshold Setting Gi: 24212010
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2FB2_A 189 IEIRFIEFMDVGNDNGWd---fSKVVTKDEMLTMIEQHFEIDPVe-PKYf--GEVAKYYRH----KDNGv--qFGLITSV 256 Staphylococcus aureus
Q88K11 180 YELRFIELMRMGHLAQHaqafrTQFVGQRELLELIGERYAFTQAe-APV---DSTALRYSV------GErg-aFGIIANE 248 Pseudomonas putida KT...
Q88LG4 195 FELRFIELMRMGHLSHDrnaflQQFVGLDQLLALIGGQHAYAQVn-APL---DATAMRYHI------PGrg-hFGVIANE 263 Pseudomonas putida KT...
P9WJS1 211 YQLRVIEQMPLDAGHSWr---rNIALSADDVLAALRPHFRLRPDp-APRg--SAPAELWLVdagpNTPRg--rFGVIASV 282 Mycobacterium tubercu...
Q8ZYE5 181 AALQFIELMPSGWGA-------SVFNELYEPIETLVNIIFELGGrpAGVrkeLHNRPLYNI----AGVT----VELIKNF 245 Pyrobaculum aerophilu...
Q9HKZ7 179 AILQLIEYETDREGESS-----EEYRRYHISLDPIEAQIRKKAIg-VEYn-dLHNRPRYLM----KNDHgvvkIEFVKPQ 247 Thermoplasma acidophi...
O27593 179 AVLQIIELLKTESCHD------DAVERYHCDITPIEAELAEMADr-IRTrkfMQDRKKYYI----DGGE----IEVVRPM 243 Methanothermobacter t...
Q980F0 177 NEIHLIELHPVGLG--------KLAFKEHDDLREIEEYIEKISIk-KLIr-kKHFRPRYVL----PSGLi---VEVVKPY 239 Saccharolobus solfata...
Q971H1 177 DELHLIELHPVGLG--------KNTFEYHEKLESIEKILKERADk-IEIr-sKHYRPRYYL----NNLV----IEVVKPY 238 Sulfurisphaera tokoda...
P59038 188 LTVRFMELQPFDDHQIWr---tGRFMGAERIRERLADAYPELEAi-T-----GHSTEHYSFs--lPGHRg--sIAIIPAF 254 Chlorobaculum tepidum...
2FB2_A 257 SQS-FCSTCTAAALSSDGKFYGCLFATVDgFNVKAFIRSGv-TDEE---LKEQFKALWQIRDDRYS 317 Staphylococcus aureus
Q88K11 249 SAP-FCRSCSRLRLSSTGRLYGCLSSNRG-HFMGTLLDLP--TEQAqpqLTALLGRALADKQDATF 310 Pseudomonas putida KT2440
Q88LG4 264 SVP-FCRTCSRLRLSSTGWLHGCLSSGNR-HFVGDLLEKP--RHQAlpaLQRLLVKALADKQDVAF 325 Pseudomonas putida KT2440
P9WJS1 283 SHA-FCSTCDRTRLTADGQIRSCLFSTEE-TDLRRLLRGGa-DDDA---IEAAWRAAMWSKPAGHG 342 Mycobacterium tuberculosis H37Rv
Q8ZYE5 246 SNPtFCSGCTTMRLTSDGKLKTCIYADSS-VDLMPYIKSRdvEG-----LLYAVRTALARREPRFK 305 Pyrobaculum aerophilum str. IM2
Q9HKZ7 248 RNPdFCAHCTRLRITSRGEFKTCLMRSDTnVPFKGVTDENr--------LRDLFRIAVSLREPYWK 305 Thermoplasma acidophilum DSM 1728
O27593 244 DNTrFCANCTRLRVTPDGKLKPCLLRNDNlVDTRDALRENdtGR-----LRELFFEAIRRRSPYYT 304 Methanothermobacter thermautotrophi...
Q980F0 240 ANPiFCAGCNRIRLSVDGKLKTCLYREDNvIDVLDILKGEysEDVKeelLGRAFMIAIAIREPNFK 305 Saccharolobus solfataricus P2
Q971H1 239 ANPiFCAGCNRIRLTADGKLKTCLYRQDKeIDIMDILRGDfsLEEKielIREAYEIAIAIREPNFK 304 Sulfurisphaera tokodaii str. 7
P59038 255 SRN-FCSSCSKLRITADARLISCLYHHES-IDLAPALKGEm-NEVE---LKKRIIEAVQQKPKDGL 314 Chlorobaculum tepidum TLS
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