Conserved Protein Domain Family
Mgm101p

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pfam06420: Mgm101p 
Mitochondrial genome maintenance MGM101
The mgm101 gene was identified as essential for maintenance of the mitochondrial genome in Saccharomyces cerevisiae. Based on its DNA-binding activity, and experimental work with a temperature-sensitive mgm101 mutant, it has been proposed that the mgm101 gene product performs an essential function in the repair of oxidatively damaged mitochondrial DNA.
Statistics
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PSSM-Id: 399431
View PSSM: pfam06420
Aligned: 46 rows
Threshold Bit Score: 212.454
Threshold Setting Gi: 575476704
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_011108443  92 DWSRSFSGLSQTPFAKEVSDVLLQPLDPAEVEIKPDGIIYLPEIKYRRILNRAFGPGGWGLAPRGETQISEKpngggI-- 169 Dactylellina ha...
EKC99387     138 DWTTSYRGLSTRPFTPEAAAALLRPLSSEDVEIKPDGLLYLPEIKYRRTLNMAFGPGGWGMVPRSEVEVGPR-----I-- 210 Trichosporon as...
XP_001732005  99 EWHSGYQGIGLRPFPAQVAHVLCEPVDKNDVEIKPDGLLYLPEIKYRRILNRAFGPGGWGLAPQGEPEVSQG-----I-- 171 Malassezia glob...
XP_012192011 155 EWGTSFAGLGERSFSREAIDVLMAPVNEGDVEIKPDGLIYLPEIKYRRILNKAFGPGGWGMAPRSETNVGQG-----I-- 227 Pseudozyma hube...
EDV25505      55 teKDDFVGIAASPFPKESADILMAPVKAEDVEVKPDGLLYLPEIRYRRILNQAFGPGGWALMPRGQPTMINN-----Ege 129 Trichoplax adha...
EFC42728      72 nGTTVYERIGKQPFSEEIAQILMAPLPDQDIEVKPDGILYLPEIKYRRILNKAFGPGGWCLVPLSEFKIERG-----S-- 144 Naegleria gruberi
Q8MYF0        72 yQEDKYQGISKEPFSKEIVDTLLADLNPDDIEIKPDGLIYLPEIKYRRILNQAFGPGGWALKPFGPPVVEGK-----T-- 144 Dictyostelium d...
EGC36966      58 ySEEKYQGISKEGFPKDVTDVLLAELNPVDIEIKPDGLIYLPEIKYRRILNQAFGPGGWALKPFGPPVVEHK-----T-- 130 Dictyostelium p...
EFA83373     114 yQEEKYHGISKEPFAREISDILLAELNNHDIEIKPDGMLYLPEIKYRRILNQAFGPGGWALKPMGPPIVENQ-----S-- 186 Heterostelium a...
XP_004362560  82 ySEEKFIGIAKEPFAKEINNILMGELDSQDIEIKPDGIIYLPEIKYRRILNQAFGPGGWALKPFGPPVVIDG-----S-- 154 Cavenderia fasc...
XP_011108443 170 ----VTREYALVCHGRLVSVARGEQDYFDEFG--IPTAMEACKSNAMMRCCKDLGVASELWDPRFIRKWKKENASELFGE 243 Dactylellina ha...
EKC99387     211 ----VSREWALVCLGRLVAVARGEQEYFDPSG--VPTAIEASKSNALMRCCKDLGVASELWDPRFIRKFKAEHCVEAMVE 284 Trichosporon as...
XP_001732005 172 ----LSREWTLICLGRFVSTARGEQEFFKPTG--IPTANEGAKSNALMRCCKDLGIASELWDPRFIRQFKAKHCVEVWCQ 245 Malassezia glob...
XP_012192011 228 ----VSREWVLICQGRFVATARGEQEFFKPSG--VPTASEGAKSNALMRCCKDLGISSELWDPRFIRQFRKKHCVEVWAQ 301 Pseudozyma hube...
EDV25505     130 lsqlVIREFALYVGGRFVAQSVGEHLHYSKNElsTGKALESAKSNALMRCCKDLGVASELWDPTFVYNFKKNHCVEVWCE 209 Trichoplax adha...
EFC42728     145 ----ILQEYGLFCRGQFVSQSFGEQTVDEQGYksIGSSLEGAKSNALMRCCKDIGIGSELWDPNFIIAWRAKNVVEAFCE 220 Naegleria gruberi
Q8MYF0       145 ----LIRPYALYCLGRYVAESIGEQQYVPNSFisFATATESAKSNALVRCCKDLGIGSSLWDPIFIRQWKSEYATERWCE 220 Dictyostelium d...
EGC36966     131 ----LMRPYALYCQGRYVSESIGEQAYFEGSFisFATATEAAKSNALVRCCKDLGVGSSLWDPTFIRQWKSLYATEKTFE 206 Dictyostelium p...
EFA83373     187 ----LIRPYALYCLGRYISESIGEQPYSDSGFisFATATEAAKSNALVRCCKDLGIGSSLWDPNFIRAWKQQFAIERFYE 262 Heterostelium a...
XP_004362560 155 ----LIRPYALYCMGRYVSESLGEQPYVEGGHlsFATANEAAKSNALVRCCKDLGIGSSLWDPTFIREWKQNNAEEKFYV 230 Cavenderia fasc...
XP_011108443 244 HV-VTKKKKKLWVRKGD--SL-DYPY 265 Dactylellina haptotyla CBS 200.50
EKC99387     285 HQ-RDKKKRKLWRRKDA--KF-EYPY 306 Trichosporon asahii var. asahii CBS 8904
XP_001732005 246 T--SDGKKKRYWRRKDDe-PF-QYPA 267 Malassezia globosa CBS 7966
XP_012192011 302 D--TTGKKKKLWRRKDDp-AF-EYPW 323 Pseudozyma hubeiensis SY62
EDV25505     210 NArNSKEKRKLWRLKRQgnDVlPYPW 235 Trichoplax adhaerens
EFC42728     221 HV-TKKTTKKLFRRHDR--EF-TYPY 242 Naegleria gruberi
Q8MYF0       221 NS-KTKERRLFWFLSNRseNQlPYPW 245 Dictyostelium discoideum
EGC36966     207 NV-KSKDRKVFWVLNNGipNQlPYPW 231 Dictyostelium purpureum
EFA83373     263 NV-KTKEKKKLWTTKSN--PApGYPW 285 Heterostelium album PN500
XP_004362560 231 HV-KTNDKKKLWTLKDGsnPM-GYPW 254 Cavenderia fasciculata
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