Conserved Protein Domain Family
AP3D1

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pfam06375: AP3D1 
AP-3 complex subunit delta-1
AP-3 complex subunit delta-1 (AP3D1) is part of the AP-3 complex, an adaptor-related complex which is not clathrin- associated. The complex is associated with the Golgi region as well as more peripheral structures. AP3D1 is required for efficient transport of VSV-G (vesicular stomatitis virus glycoprotein) from the trans-Golgi network to the cell surface.
Statistics
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PSSM-Id: 399400
Aligned: 20 rows
Threshold Bit Score: 109.051
Threshold Setting Gi: 514691494
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDW00467      684 TPEQMERQRVARLIEQSNNPHYLKSTPISSsiaigisSNNSNADQY-DNIDDIPITEIPLDiegvVAL-RVGIt-KRSDK 760  Drosophila gr...
XP_004993320  663 DEEDLRRRRQVRMAAQAANPYHLGQYATPSgg---ttSMASSQQISqEEVDQIPVRTLDLGpsikLDVaPVPG--TGLDF 737  Salpingoeca r...
XP_018671411  658 SQEELNKLREERMVEQANNPNYLMS------------KKAEGYMNP-DEESEAGSINLDIS----VPL-HVPGl-PSSDR 718  vase tunicate
EFX74641      669 yQGEGQVRREALRVEQASNPHYLKGSSQAR-------RSPSSSSQLlSPTEEIPVMSINLS----VPL-QVSTskKLSDK 736  common water ...
XP_008209671  658 TAEELEIRREARKLEQQNNPHYLKNSTVPNk-----kISFYDKPGNdEDFENIPITQLDIP----ISL-KVTN---PINK 724  jewel wasp
EFN74144      598 sLEELERRREARKLEQENNPHYLKGSFKTS-------TSYHNSSSVyEDFENIPVAELDIP----ISL-KISN------- 658  Florida carpe...
ESN98976      669 TEEELASRREMRKLEQVNNPHYLRGST----------KNKMKTSNGaQFASGVPVVELDLP----VAL-NVPGl-ASSDK 732  Helobdella ro...
XP_002435044  428 apfPLAQMREARKQEQANNPHYLKATPKS--------RSSNGHIQG-VGVEDIPVAEIDLS----VPL-HIPGl-ISSDK 492  black-legged ...
XP_001149847  661 DEEELARRREARKQEQANNPFYIKSSPSPQ-------KRYQDTPGV----EHIPVVQIDLS----VPL-KVPGl-PMSDQ 723  chimpanzee
XP_310978     692 gsRSYKRIEQARLLEQTNNPNYLKPAKTKKasg-gdyHHQQQQQQH-DCYDDIPIAEIALE----VPL-QIHSt-KRSDK 763  Anopheles gam...
EDW00467      761 YLQTlqa---------ttSLSSKDAKRKHKKGKKSKK------SKNKVA-----YNSSSESEAEPKPLHL-----VN--T 813  Drosophila gr...
XP_004993320  738 GVED--------------DTEKKKKKDKKKRKKKRKKlskkeiRRLKKKglpipEGPPSSSDEDDDDHHRaaaakIDilA 803  Salpingoeca r...
XP_018671411  719 YFKMeqdrr----rrqraE------RVVKKKKAKRGK------HGRKRE-----EQEEPEEEEDIAPVHA-----VEi-V 771  vase tunicate
EFX74641      737 YLELern--------keaSSDSKKHRSKRDKKKKKKK--------------------GSSDEEEAAEIVA-----PQviS 783  common water ...
XP_008209671  725 YYDMnrvdesdrkrhkktS--------KKKKSKKNKK------------------SSSSEDDDDSYPIQL-----VNk-G 772  jewel wasp
EFN74144      659 NLHRcrnidsshkrhkkhE------KKKKSKHNKNKK-----------------SASEEDELDDSLPLQI-----VNt-G 709  Florida carpe...
ESN98976      733 YMKLakq---------qeDDDNIKKKKKKTKIGKKKK------HANKKR-----DENDEEDDDNGDDAGIdkrtvVr--T 790  Helobdella ro...
XP_002435044  493 YLSAsrka------revaDGEEGGDRRKKKKKRRRRKg----eEEEEEK-----RPPPEVPSEEELPAEA-----VNt-S 551  black-legged ...
XP_001149847  724 YVKLeeerr----hrqklE----KDKRRKKRKEKEKK-------GKRRH-----SSLPTESDEDIAPAQQ-----VDi-V 777  chimpanzee
XP_310978     764 YLMDaerat----rvfvgKSGGRKEKGEKS-GKKSKRr----gKKSKRY-----SDESDSESDDPKPLHV-----VN--T 822  Anopheles gam...
EDW00467      814 TLDMPEGVTLS--DSEDkdgkyDPNDPHRALDIELD 847  Drosophila grimshawi
XP_004993320  804 QEDMPEGAEESggDEEP-----AVDDPHAALNIDLE 834  Salpingoeca rosetta
XP_018671411  772 NEEMPEGAVKT--DSEDe---nPSIDPHKALDIDLD 802  vase tunicate
EFX74641      784 TMELPEGARLS--DSEDdg--rPQTDPHRALNIDLE 815  common water flea
XP_008209671  773 IGELPPGAALS--DSDNdd-tkDVNDPHRALNIDLD 805  jewel wasp
EFN74144      710 VGELPPGAEIS--DSDDyd-liDANDPHRALNIDLD 742  Florida carpenter ant
ESN98976      791 TVEMPDGVELS--DSDMks-stPSNDPHKLLDINLD 823  Helobdella robusta
XP_002435044  552 LGEMPEGARLT--DDEDdd--rHKDDPHRALDIDLE 583  black-legged tick
XP_001149847  778 TEEMPENALPS--DEDDk----DPNDPYRALDIDLD 807  chimpanzee
XP_310978     823 VIELPEGAILS--DTEDkn-naDPNDPHRALDIDLD 855  Anopheles gambiae str. PEST
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