Conserved Protein Domain Family
PITH

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pfam06201: PITH 
PITH domain
This family was formerly known as DUF1000. The full-length, Txnl1, protein which is a probable component of the 26S proteasome, uses its C-terminal, PITH, domain to associate specifically with the 26S proteasome. PITH derives from proteasome-interacting thioredoxin domain.
Statistics
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PSSM-Id: 399305
Aligned: 302 rows
Threshold Bit Score: 57.221
Threshold Setting Gi: 402468778
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ESS34159      58 HFVDWTNVHCLNdscqepfps-rdwragrprKGqrFVSS-ADDaQLIIHIPFN-RKVKLMGISLgihpdqvqhG----PS 130 Toxoplasma gond...
XP_006689299  43 SKIDTPHVTALNlanppedlqklfkkpqnkyELkpVVASdCDS-QLIINIPFLnGSVKLFSLIIrtng------dkycPK 115 Yamadazyma tenu...
XP_004202254  42 SKVDVPHVRALNmanppeevqklfktqadkyRLkpVVRSdCDA-QLILHIPFVnSSVKLHSLILrtng------dkycPK 114 Pichia farinosa...
CCE43538      39 SKIDTFKVSALNmanqpddlakifktpdkkyEIrpTIKSdCDE-QLIINIPFLnGSVKLYSLILrtng------ssycPK 111 Candida parapsi...
XP_001528795  38 SKVDLDKVSALNmanpksdlarifksaetkyEVkpVIRSdCDE-QLIIIIPFLnGSVKLYSLILrtng------eeycPK 110 Lodderomyces el...
Q5AH92        34 NKIDTSKVTALNmansaddlakvfkdstkkyQIkpIIKSdSDE-QMIINIPFLnGSVKLYSIILrtng------dlycPK 106 Candida albicans
EER34316      38 SKIDTTKVTALNlanpsdelaklfkdsntkyQVkpVIKSdCDE-QLIINIPFLnGSVKLYSIILrtng------diycPR 110 Candida tropica...
XP_007374989  41 SKIDTSKLTALNmanptddlaklfktsetkyHIkpIIKSdCDC-QLIINIPFLnGNVKLYSIIFrtng------dkycPR 113 Spathaspora pas...
XP_002493854  25 TQIDFTKLTALNcttpnsklyei--fihegeeskitLSSdCDN-QLILNIPFV-SSVKLYSLILkt-----spDndhcPK 95  Komagataella ph...
ESW99525      23 SHVLTTQLVALNvanpssdleklfktqtnkyEVipEIRSdADN-QFILRIPFQ-GSVKLYSIILrt-----arQpdhcPR 95  Ogataea parapol...
ESS34159     131 VIHLYKDlPTFDFSDA---------VSVkplhtlhllpedlcRshdstaQSPkPgnSgSKrgssPfnsStlgpiasArnL 201 Toxoplasma gond...
XP_006689299 116 TIKLWKNdKNIDFDNAstkkptfqiEHP--------------Hvgv-myNEDdGt---MP----EsldS-------DieF 166 Yamadazyma tenu...
XP_004202254 115 TIKLWKNdKAVDFDNCtskrptwtlTHP--------------Lvgv-afNDD------VP----EvleS-------DdsF 162 Pichia farinosa...
CCE43538     112 TIRLFKNdKMIDFDNIeskkpvqtiTHP--------------Qvgv-adDVDeSe---------DiveS-------DndF 160 Candida parapsi...
XP_001528795 111 VIKLFKNdTSIDFDNLegkkptqtiNHP--------------Qigl-atDIDdE--DgQQ----TvveS-------EdtF 162 Lodderomyces el...
Q5AH92       107 TIKLFKNdTSIDFDNVdskkpiqvlTHP--------------Qvgv-anNDSdD----LP----EfleSn-----nDddF 158 Candida albicans
EER34316     111 TIKLFKNdKTIDFDNVdqkkpvqviTHP--------------Qigv-anDDD------LP----EilqS-------DddF 158 Candida tropica...
XP_007374989 114 TIKFFKNdKTIDFDNVdtktptqkvKHP--------------Qvgl-svDEDdE--EnIP----EvveE-------EgdF 165 Spathaspora pas...
XP_002493854  96 KISLFKN-ADVDFETTapkn-thhfEQP----------------------------------------L-------VgeF 126 Komagataella ph...
ESW99525      96 IIKLYKNqDSLDFDSVgdtkatheiEQP--------------Qigl-eiDGElPreVvADd-----------------tF 143 Ogataea parapol...
ESS34159     202 PptAVPLPalLFGVTSSLWLFIEENQGG--KDVTKISTMQVWG 242 Toxoplasma gondii VEG
XP_006689299 167 VehFLPRH--IFTGVQSLTVFVEDIHNNddEDETRLHYVELRG 207 Yamadazyma tenuis ATCC 10573
XP_004202254 163 VehFLPRH--LFTGVQHLTVFVEDIH-DdsEDESHLHYVELRG 202 Pichia farinosa CBS 7064
CCE43538     161 VehFLQRH--KFTGVQQLTIFIADIY-DesEDQCRIHSIELRG 200 Candida parapsilosis
XP_001528795 163 VehYLSRP--KFTGVEQLTLVVESIH-DesEDQSRIHLIELRG 202 Lodderomyces elongisporus NRRL YB-4239
Q5AH92       159 VehYVSRH--KFTGVNQLTIFIEDIY-DegEEECHLHSIELRG 198 Candida albicans
EER34316     159 VehFVSRH--KFTGVQTLTLFIENIY-DegEEECHLHSIELRG 198 Candida tropicalis MYA-3404
XP_007374989 166 VehFLSRS--KFTGVHHLTVFIEDIYDDedEDECWLHSIELRG 206 Spathaspora passalidarum NRRL Y-27907
XP_002493854 127 VehHLPRR--LFTNVHKLTIFFEGNWSNdeFESLEILGIELRG 167 Komagataella phaffii GS115
ESW99525     144 VehYLPRH--HFSGVSSLTLFFQNNWSDndDEVLKLYSIELRG 184 Ogataea parapolymorpha DL-1
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