1GHH


Conserved Protein Domain Family
DinI

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pfam06183: DinI 
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DinI-like family
This family of short proteins includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co- protease activity of RecA. Escherichia coli DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed in vivo. Biochemical and genetic studies indicated that DinI physically interacts with RecA to inhibit its co-protease activity. The structure of DinI is known.
Statistics
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PSSM-Id: 399293
Aligned: 27 rows
Threshold Bit Score: 67.2829
Threshold Setting Gi: 238868502
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GHH_A           14 PAGAIDALAGELSRRIQYAFPDneGHVSVRYAAANNLSVIG-ATKEDKQRISEILQETWESADDWF 78  Escherichia coli
P0A1G3           15 lPGAREIILNELTKRVHQLFPD--AQVKVKPMQANALNSD--CTKTEKERLHRMLEEMFEEADMWL 76  Salmonella enterica subsp....
CAX59238         15 lpNAQELILNELEKRIQRVFPA--AEVKVKPMQANGVKTD--ASKSDKSVMLRIIEEMFDEADQWL 76  Erwinia billingiae Eb661
IEC:ABF-0016414  15 lpNAAEQIKNELAKRIHRVFPD--AEIKIKPMQANAINSN--ASKQDKSTINRIIEEMFNEADEWL 76  Dickeya dadantii 3937
jgi:Rahaq2_1379  15 ipnASEKIEAELVKRVHRLFPE--AEVKVKPMQANGLNTHG-ASKQERSQLNQMLEEMFEEADDWL 77  Rahnella aquatilis CIP 78....
BAN99305         14 SQSVVDAFREEVDKRVIALFPN--AVVQVRQGSYNKIEMPGvEVDEDRRRLNDLLQNVWAD-DSWL 76  Plautia stali symbiont
wugsc:KPN_04886  98 GQPVIDAFQCELTRRIQSVFPS--TRVTVRKGSMTGVELMGfDKDSDREALDSILQEVWED-ESWR 160 Klebsiella pneumoniae subs...
Q8ZMS6           38 SQSTLDALESELYRNLRPLYPK--TVIRIRKGSSNGVELTGlQLDEERKQVMKIMQKVWED-DSWL 100 Salmonella enterica subsp....
CCH:MU9_2984     14 PAHLIQSLEVQLKRRILPLYPD--MQFRIAQSSQTTINISGvKSPDDKQSLMDTIQTIWED-DSWM 76  Morganella morganii subsp....
CBJ80524         14 SESVMSALESELKKRILPQYPD--THFRIAVSSSSSVRVTGtKDSSKHDQMMELIQNVWED-DSWL 76  Xenorhabdus bovienii SS-2004
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