4V1O


Conserved Protein Domain Family
Med22

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pfam06179: Med22 
Surfeit locus protein 5 subunit 22 of Mediator complex
This family consists of several eukaryotic Surfeit locus protein 5 (SURF5) sequences. The human Surfeit locus has been mapped on chromosome 9q34.1. The locus includes six tightly clustered housekeeping genes (Surf1-6), and the gene organisation is similar in human, mouse and chicken Surfeit locus. The Med22 subunit of Mediator complex is part of the essential core head region.
Statistics
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PSSM-Id: 399290
Aligned: 54 rows
Threshold Bit Score: 56.4319
Threshold Setting Gi: 835898841
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4V1O_Z                7 EKLEQTRTILSVKLAELINMTTI--ADRNDDdegsfaqensELA---VATTSVMMVNNQTMQLIKNVQDLLILTRSIKEK 81 
XP_013024715         19 ASIDGATQTLLSRFQDIADIAMNqrKDKHTV------------------SSEVYQIECHTLSMIRAVEQLLDISRQLKSF 80  Schizosa...
XP_001526574         10 QKVDTIVEQLLLKFQDIFEVLK---NDNKPK----------ELL-----AVESLTIENNAIQIIRLCQDMLSILRSLKET 71  Lodderom...
EHK15327             13 dnhnRLVADILTRYRTLMMLATV--QAEQDR----------NNAnpeAMAVTGISIKMEFDGLYTSIKEFLTLSRKIKEL 80  Trichode...
EQB55717             12 DTHNRLIADVLSRFRMLTMLATI--QAEGER----------KNAepqTVAVTGMSMQMEFEGLHTSVKDLLALSRRLKEL 79  Colletot...
XP_006692621         13 ERKNILIASIMTSYRDLITHATS----PITS----------ATAspgHAGYSSMALSTAIHAAVKYTEDLLSLTRTLREL 78  Chaetomi...
KLU90261             11 DREQKTLSDILSRYGGVMMAATT-----GVD----------GQStvgSAAYNSMQMELELKGLVKSTEDLLTLTRLLREL 75  Magnapor...
EHA51793             16 DRHQAAITDITKHFGELVIGLSS----PITA----------EDAdtaTSSQQAMRMQLESNALIASIEHLLSLTRQVREL 81  Pyricula...
WGS:AACS:CC1G_10948  54 KKVDVEVETLVNGMVDLVNLASIgeKDKFTV------------------AQEAFAAQSRAESMVRAANSLLSIVHSMKLL 115 Coprinop...
ESK95359             47 KKVDLEVETLVDGMVDLVGLASIgdKDKFRI------------------AQESLQAQLRAESMVRAANSLLSITHSMKLL 108 Moniliop...
4V1O_Z               82 WLL----------------NQIPVTeHS---KVTRFDEk--qIEELLDNCIETFVA 116
XP_013024715         81 WLC----------------NSSPTTvPSlsyNETDLVGlrtkLTS-LQNIGLDVKN 119 Schizosaccharomyces cryophilus OY26
XP_001526574         72 WILqtlkvrntgdayntgnNDINGTnNDikdQ-RGCGEwneeESQKVFNLFNELTE 126 Lodderomyces elongisporus NRRL Y...
EHK15327             81 WIF----------------GPLGTEdSDrkeKEEQLDQdvnrVSELLNQMEASKMK 120 Trichoderma virens Gv29-8
EQB55717             80 WLF----------------GKLGAGeSDariQADKLQAdvvrCAELLNAIQEtrys 119 Colletotrichum gloeosporioides C...
XP_006692621         79 WVV----------------GPLTGPgEKdaqAEEGMAKdaevVWDVLNEMRDrere 118 Chaetomium thermophilum var. the...
KLU90261             76 WLV----------------GPLMKPgEGervAEETIDGhvqaTAALMAHLRDQSRK 115 Magnaporthiopsis poae ATCC 64411
EHA51793             82 WLV----------------GPLLKPgEGeraADGQIDEqvesMTHILNQLRERVRN 121 Pyricularia oryzae 70-15
WGS:AACS:CC1G_10948 116 LLL----------------SDESQTaHRrdaEEKEIREaneeTKRKVAALLDELLR 155 Coprinopsis cinerea okayama7#130
ESK95359            109 LLL----------------SDEAQIaNRrdtELNQVYQerdeAKAKVAALLDELLR 148 Moniliophthora roreri MCA 2997
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