Conserved Protein Domain Family
Shigella_OspC

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pfam06128: Shigella_OspC 
Shigella flexneri OspC protein
This family consists of the Shigella flexneri specific protein OspC. The function of this family is unknown but it is thought that Osp proteins may be involved in post invasion events related to virulence. Since bacterial pathogens adapt to multiple environments during the course of infecting a host, it has been proposed that Shigella evolved a mechanism to take advantage of a unique intracellular cue, which is mediated through MxiE, to express proteins when the organizm reaches the eukaryotic cytosol.
Statistics
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PSSM-Id: 283728
Aligned: 2 rows
Threshold Bit Score: 553.491
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q326U4 191 VEISNHQEKLPLNKTHHTVDFGANAYIIDHDSPYGYMTLTDHFDNAIPPVFYHEHQSfFLDNFKEVVDEVSRYVHGNQGK 270 Shigella dysenteriae ...
Q327E0 186 VEISSHQKKHPLNTKHHTVDFGANAYMIEHSSPYGYMTLTDHFDNVIPFAQYHEHQS-FLDKFSEVNEEVSRYVHGSKGI 264 Shigella dysenteriae ...
Q326U4 271 TDVPIFNTKDMRLGIGLHLIDFIRKSKDQGFREFCYNKNIDPVSLDRIINFVFQLEYHIPRMLSTDNFKKIKLRDISLED 350 Shigella dysenteriae ...
Q327E0 265 IDVPIFNTKDMKLGLGLYLIDFIRKSEDQSFKEFCYEKNLSPVDLDRIINFVFQPEYHIPRMVSTENFKKVKIREISLEE 344 Shigella dysenteriae ...
Q326U4 351 AIKASNYEEINNKVTDKKMAHQALAYSLGNKKADIALYLLSKFNFTKQDVAEMEKmnnnrycNLYDVEYLLSKDGANYKV 430 Shigella dysenteriae ...
Q327E0 345 AVTASNYEEINKQVTNKKIALQALFFSITNKKEDVALYILSNFEITKQDVISIKH-------ELYDIEYLLSAHNSSCKV 417 Shigella dysenteriae ...
Q326U4 431 LEYFINNGLVDVNKKFQKVNSGDTMLDNAMKSKDSKMIDFLLKNGAILGKRF 482 Shigella dysenteriae Sd197
Q327E0 418 LEYFINKGLVDVNTKFKKTNSGDCMLDNAIKYENAEMIKLLLKYGATSDNKY 469 Shigella dysenteriae Sd197
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