5J3Q


Conserved Protein Domain Family
DCP1

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pfam06058: DCP1 
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Dcp1-like decapping family
An essential step in mRNA turnover is decapping. In yeast, two proteins have been identified that are essential for decapping, Dcp1 (this family) and Dcp2 (pfam05026). The precise role of these proteins in the decapping reaction have not been established. Evidence suggests that the Dcp1 may enhance the function of Dcp2.
Statistics
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PSSM-Id: 399212
Aligned: 72 rows
Threshold Bit Score: 76.8143
Threshold Setting Gi: 154421245
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5J3Q_A                     11 RNAVNLQVLKF--HYPE-IESIIDIASHVAVYQFDVG-SqkWLKTSIEGTFF--LVKD-----QR-ARVGYVILN--RNS 76   f...
Q8IJ85                    295 REKICFKMLKS--IDIY-ITEIIMKSCFVTVYKMKDD-ElkWKRADIEGFLY--IVKR-----SIkPYYRLIITN--KKN 361  P...
EDO08414                   28 RGRLSLKLLLS--CDQH-VKDIIFQTPFVTAYELKG--NneWERAGIEGFLY--LLQR-----DAePAHSIIVVN--RKL 93   B...
Q4U8T6                     27 RGRLSLKLLMT--LDPY-IETILHQTPFVTGYHMTS--QdkWSRMGIEGFLY--VVTR-----TKsPKHSFILVN--KKS 92   T...
XP_001583636               16 RKDTNLRVIRKifQEVGyIQDYLNVYPEVCIYKKSE--DgrWVKLQIGGPLFlcVVQNq-------TDLTLFLLNntQTN 86   T...
WGS:AAFB:cds.EHI_042970A   19 IQLINLRALQG--FFPI-IESVIMNCGVVSVYELRSEgGkeITDVGCRGPLF--LVQT-----RH-KELWLVVLN--QSS 85   E...
EIJ87698                    8 tNEVTNRMLKG--KDAQ-YSHLLLTSINVLVLKY----EnkWINTCTEGAIH--LYKR-----KIiPSTCILVLN--RKA 71   N...
XP_007604018               22 QRKIVDRYLLS--IDNL-YSKLVFTTGKVILYIFE---NneWIEMNLEGPLY--LYRRnneenVS-SQYRLIVLS--RNN 90   V...
ELA46446                    7 QSSILQRVLQR--YDPS-FHSTIYTSSHVALYKY----TtkWDRTSTEGNII--IYRR-----TTlPSTKLVIFN--KKD 70   V...
Q8SU45                      6 DGQILMREIGR--ADPL-LKDLLYVSSFASVYRH--A-NgeWNKLNIEGTFV--MYTR-----ALcPPVGIHVFN--RKS 70   E...
5J3Q_A                     77 PE-NLYLFINHP-SNVHLVDRYLIHRTENQ------HVVGLWMFDPNDMSRIF 121  fission yeast
Q8IJ85                    362 EK-HLLQDIDTN-MNLSTDQNYIFYRIINEetn-vrNIYSLWFYSTEEKEQIY 411  Plasmodium falciparum 3D7
EDO08414                   94 EH-HLIEYITPE-FQVALEGNFIFYRSLNTatgtmhNIRGLWFYDEKECMTTY 144  Babesia bovis
Q4U8T6                     93 EN-HLIEYLTPE-FQMNSSGNFIFYRSLDItknflnNLQGLWFFDENECKTTY 143  Theileria annulata
XP_001583636               87 EEsSFYKKLNPQ-TRYAIQGNQLYIKTDQEs----dMVYS--FHDERDVQDLI 132  Trichomonas vaginalis G3
WGS:AAFB:cds.EHI_042970A   86 F--GIYHTIVSEqTQFQQQDRYLTLTHLDNq-----CLVQFCFISQSANEECT 131  Entamoeba histolytica HM-1:IMSS
EIJ87698                   72 PA-DFHLLIDKAvHGIEIFDRFIIIKIAHKke---iEVFGLWFYDKQSCAQAG 120  Nematocida parisii ERTm3
XP_007604018               91 MQ-DFKLNIPNS-FYLECQNQAVVFSHLDKn-----NIFGFWFDNELVVKKFY 136  Vittaforma corneae ATCC 50505
ELA46446                   71 RG-VFEVYLGG--IEVDMVRDIIVFKNEA-------FCYGIWMVVEREREVLV 113  Vavraia culicis subsp. flori...
Q8SU45                     71 LK-DFTLYLTKD-IRFGVKGNFMTLSDDESg-----EVYGLWLHSDAHPGEVL 116  Encephalitozoon cuniculi
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