Conserved Protein Domain Family
NnrS

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pfam05940: NnrS 
NnrS protein
This family consists of several bacterial NnrS like proteins. NnrS is a putative heme-Cu protein (NnrS) and a member of the short-chain dehydrogenase family. Expression of nnrS is dependent on the transcriptional regulator NnrR, which also regulates expression of genes required for the reduction of nitrite to nitrous oxide, including nirK and nor. NnrS is a haem- and copper-containing membrane protein. Genes encoding putative orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase.
Statistics
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PSSM-Id: 399144
Aligned: 201 rows
Threshold Bit Score: 88.8415
Threshold Setting Gi: 501047332
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Tmz1t_1808   2 CGFRPFFLLTALHAVLVLLAWGgfLgf------glALPAVAGGPFVWHAHELMFGFGLAAVAGFVLTAVPEFTA-T--PA 72  Thauera sp. MZ1T
Q7NUI7          34 APHRAAFLPGMLLAILLLAAWS--AelaarlfglgLPL--ALPAMLAHGFLMLFGFFPLFMAGFLFTAGPRWLN-V--PP 106 Chromobacteri...
WP_011803902    41 APHRLGFFLAMLLLMASGLWWA--Lvqidr-vsgaLALPYGVAPSLVHAAVMTFGFMPLFFAGFLFTAGPKWLH-V--EP 114 Acidovorax sp...
EHR73511        39 APHRVAFFAGAVVLAAAALWWT--Aalla--rhagLALPWDVRPGTAHALVMGLGFMPFFFVGFLFTAGPRWLQ-Q--PA 111 Burkholderial...
jgi:Mpe_A1702   32 APHRLAFFAGGVALAATGLWWA--Lmlal--rhagIATPWAVVPPVAHGLLMAVAFNPLFMIGFLFTAGPRWLG-L--PD 104 Methylibium p...
jgi:Lcho_1485   36 APHRLLFFAAALLWSAIAVWWAavMaas----plgWTLPWAVAPAPAHALLMTLGFMPLFIAGFLFTAGPTWLR-LaaPS 110 Leptothrix ch...
WP_014236729     8 APHRVMFALGALQSLLAVLFWA--AdlggryaglyGAPAWALPGIWLHGALMLFGLFPPFIFGFLMTALPKWVS-A--PA 82  Azospira oryzae
WP_025308608     6 dAYRYFFPVGWGLGVWGVFLWIl------------FPLGWVQYPGQTHPDLMLGGFFLSFVCGFLMTAAPKFTSsFepTM 73  Bdellovibrio ...
Q6MK20           7 dAYRYFFPAGWVMAVWGVLLWIl------------FPWNLVTYPGLHHPEIMSGGFFLCFVAGFLMTAAPKFTAsFgpTK 74  Bdellovibrio ...
WP_012099098    28 EPYRLFFPLGAALGAIGVGDVLrqAms-----------gaVGESGLAHSLALIQGFMTAFATGFLFTFVPRRTG-T--RA 93  Anaeromyxobac...
jgi:Tmz1t_1808  73 FAPRVVLRLVLLWLAARAAFWLSGglaaVaeswlggeegqavarwighlPAALLEIGF---ACALLAAVA-PRL---WRD 145 Thauera sp. MZ1T
Q7NUI7         107 PGRGAYLL-VPALLVAGLLTWLIGaa-vGga-----------------wLLAGHLVYS---LGFLGLAGGfARL---LL- 160 Chromobacteri...
WP_011803902   115 WPVSRVMP-PLLLQAGGWLVWLAGgs-wGll-----------------vALAGCAVAF---LGLAWMTVLfIRL---VQ- 168 Acidovorax sp...
EHR73511       112 QRAADLAL-PLGLMAAGWLLALPGfh-lAaa-----------------lAALGLATAA---VGLALATGRfLLL---VL- 165 Burkholderial...
jgi:Mpe_A1702  105 VPGSSLVR-AVLAYGAAMAVLLLGvh-lHag-----------------lAAAGLLGAA---AVWTRLLWRfGRL---VR- 158 Methylibium p...
jgi:Lcho_1485  111 VPSARTLRWPALSIVIGWGVLLPGlh-lDar-----------------lAVAGLVAVA---LGWSALSGRfAGL---VRI 166 Leptothrix ch...
WP_014236729    83 LTRGQYLP-AFALLAGGWLLFWGGll-aAp------------------lAVSGLVVAS---LGWLWGLVAlARA---VTW 136 Azospira oryzae
WP_025308608    74 AEQRTAFALIALLISA---------------------------------VVFFSKVYFyftVVLLFLFLMiFLVrrfLKR 120 Bdellovibrio ...
Q6MK20          75 NEQRASLVLIGLLFAS---------------------------------LIPGSKTFFyftVTALFVFLItYMArrfLNR 121 Bdellovibrio ...
WP_012099098    94 PAAWQMALAAGAPVAAVLLHLVG--------------------------RSAAGHAAW---LAGIAVLAG-------FAA 137 Anaeromyxobac...
jgi:Tmz1t_1808 146 PE--------RRH-----LGFQWGLAAMAMAVAGFHLD---VLRGEYPMR----WVLV-GLGVMMTLVVVAMSRISMRVM 204 Thauera sp. MZ1T
Q7NUI7         161 ASpap---drRHA-----WAVLSAFGIGVLALAAag----yWLLSGDVRGwl-wMRDLaLWGFLLPVFLTVCHRMLPFFS 227 Chromobacteri...
WP_011803902   169 RStlq---drLHA-----RAIAAACLVGCVCIAAlg----lSLAGGRGDLar-aWVLTgLWGFVAAVFVVVAHRMIPFFT 235 Acidovorax sp...
EHR73511       166 QSrva---erEHA-----VLAAGGCAVTAMALWAaa----aGVALGQDAAar-aALHFaLWGGLAPVFVAVTHRMLPFFS 232 Burkholderial...
jgi:Mpe_A1702  159 ASrvp---dtLHA-----RAIVATSALGAAAMGVaa----lALAAGRVDIar-aTTAVlLWGFVAPVFAIVSHRMLPFFT 225 Methylibium p...
jgi:Lcho_1485  167 SRad----drLHA-----KGLAIATVVIVLALWLaa----lALALEHVTLlr-vATCLaLWGGLASVFALAGHRLTPFFH 232 Leptothrix ch...
WP_014236729   137 PQprgfapdrSHA-----YALLAALGLGLVALWAya----wGLAAMAGDGvr-aGIELgLWGCLLPVFFIVSHRMLPFFT 206 Azospira oryzae
WP_025308608   121 RS----------NppdafLFVGVGVLAGLAGSVGll----lGYTTNLPSFlfqlSRLFfLQAYIFCLVLGVGSRLIPALL 186 Bdellovibrio ...
Q6MK20         122 KN----------NppdsfLFVGVGLGAGLVGSLTll----lGQFVNVPSElyqlARTFfLQAYVLCLVMGVGSRLIPALL 187 Bdellovibrio ...
WP_012099098   138 RRlas---erALRrvpavFAWVPAALLLGAGGAIASAIaprLGPWPGPQVwa-lGRGMlVQGLVTGLVLGVGGILLPQLT 213 Anaeromyxobac...
jgi:Tmz1t_1808 205 HDALdaararrlpahtlrrdeEAELELPSYRARpprrnLAIAAI-------AVHTVAEYL-------------LPGSPit 264 Thauera sp. MZ1T
Q7NUI7         228 ANAL---------------------APYQPWRPwwllaAMLGGS-------LGHGLLSIAgwp----------------s 263 Chromobacteri...
WP_011803902   236 SAVL---------------------PMVQAWRPfwvlwLMLAAV-------VAEA-LAVWlpwlgwapaldtgGLLvr-- 284 Acidovorax sp...
EHR73511       233 AAAL---------------------PAQDAWRPrvllwLMVGAV-------AVQAPLAALqafdd----gpssvLLSGlr 280 Burkholderial...
jgi:Mpe_A1702  226 TSAL---------------------PLHHAWRPdallqWMLAALlatasgsAAEAMLGVLpawa-------qalLLa--- 274 Methylibium p...
jgi:Lcho_1485  233 PSIA-------------------------RRFEtgllgPVLAGL-------WLRGAADLAalws-----wpwpMPLHVll 275 Leptothrix ch...
WP_014236729   207 AAVL---------------------KNYTIYRPmpllwLVLACF-------LGHALLALVgwhg--------------al 244 Azospira oryzae
WP_025308608   187 GWVE------------------SPQEGSPQKRVflftfLAFAFI-------GSY-------------------ILEAAqv 222 Bdellovibrio ...
Q6MK20         188 GWAPl---------------pTESSKYTPQ--IklysaLAVAFL-------GSF-------------------VLEVLvq 224 Bdellovibrio ...
WP_012099098   214 RGeapp-----------dalePGANRRAALRHG-----ALALAF-------LASFPLEI--------------FRSALeg 256 Anaeromyxobac...
jgi:Tmz1t_1808 265 gwLGLGA-AAAVFNLLND-WH---VGRALFTR--WAFLLYAVYWLLALGY--LLLGLA----------RlGAPLAPSAGT 325 Thauera sp. MZ1T
Q7NUI7         264 wgLDLCL-AALFGYTSWR-WR---LLASLRVR--LLAMLHLSFAWLAAGF--ALYAWqg---------afGg--LAWAPL 323 Chromobacteri...
WP_011803902   285 gaLELSA-GAVLLWLAYR-WG---LLQSLAQR--LLAMLHIGFIWLGLAF--VGHGLAhgaqg---lygsAa--GELGAL 350 Acidovorax sp...
EHR73511       281 aaLELPA-GALMLWLALR-WG---LLQSLKIR--LLAMLHMGFFWLGVAF--TLGGVShalms--asdgtLs--LGLAPL 347 Burkholderial...
jgi:Mpe_A1702  275 --VQAPT-AVLMLWLALR-WG---LVQSFAVR--LLAMLHAGFVWLGITF--ALLAVArgmal--wqigpGs--LGLAPL 339 Methylibium p...
jgi:Lcho_1485  276 avVHGLL-GGMLLVTAFD-AS---LARARRAP--MVRLLHAGFVWLGVSF--VLESLSqavlaagrptG-----LGLAPL 341 Leptothrix ch...
WP_014236729   245 wlPDAVA-AAVVIHFSWK-WQ---LRRSLAVP--MLAMIHGATVWLGLGL--VLYACqglala------lggsfGGLAPL 309 Azospira oryzae
WP_025308608   223 giWAQALrGLVIGYIAFKfWR---IHKFPARRgvQTWWLWASAWSLLLGQaaMIF----------------FSDYRIHLL 283 Bdellovibrio ...
Q6MK20         225 plSGQILrALVMSFIVFKfWK---LHHLPQRRafQSWWLWGSAWMLLLGQwgTVA----------------FLDFRVHLL 285 Bdellovibrio ...
WP_012099098   257 laLRAAV-AGAVLLGVAR-IHrapSAPGLHRG--LVW---LSAWLLLAGY--LLAAIFp--------------kLRGAAL 313 Anaeromyxobac...
jgi:Tmz1t_1808 326 HLLAIGAMGLSILAVLCIAGRTHAGYPL-DE--RPWVGAAAVSIVLAALLRAAAglPDMPASALQ----LLATLaWITAF 398 Thauera sp. MZ1T
Q7NUI7         324 HAISVGFFLTMLIAFVSRVSLGHSGQALeA---GRMLWGLYLAAQWLALARVAAdlLPIA--WRGgmygLAALG-WLLTL 397 Chromobacteri...
WP_011803902   351 HALTMGCLGSLMLAMVTRVSCGHGGRALvA---DRLVWTLFWVLQLATVVR-LAasAP--LPWSPvllaVAALL-WAGIM 423 Acidovorax sp...
EHR73511       348 HALTMGFLGSTLVAMATRVACGHSGRSLvA---DNWAWAVFWALQAGVLLRVTAalVP--PALSTpltlLAAQF-WLAAV 421 Burkholderial...
jgi:Mpe_A1702  340 HALTVGFLGATLLAMITRVAAGHSGRPLvA---DGPALLLYGAVQLAAVARVLSalWP--DA-PValllLAAFA-WAAAA 412 Methylibium p...
jgi:Lcho_1485  342 HALSLGFMATTLLAMASRVAAGQHGRTIaI---DRTVLLMHVLLQGVTVLRLLValWPSAPSGLL----LSASFgFAALA 414 Leptothrix ch...
WP_014236729   310 HAISIGYFVSMLLGMVTRVTLGHSGRPInAG--DQTTWPLFWLFQSVPLLRIAGefLPLSGPFNlq--wLASLA-WLLVF 384 Azospira oryzae
WP_025308608   284 HVILVSGLALMTFMIATRVSLAHGKHDLgLEknSKVLFVGALLVSLAGFTRLSAgfALHIYQSHL----IYAFYtWIIGL 359 Bdellovibrio ...
Q6MK20         286 HVILVSGLGLMTFMIATRVTLSHGKHDMiWEknSKGLFLGALLMGFAGLTRLSAgfAPHIYQSHL----VYAAYtWILGL 361 Bdellovibrio ...
WP_012099098   314 HLTFVGGFALMTLAVSIHVAVTHGGRPErLAgsPAPVRAVGLLVLAATAARLLA---GIDRARLQlwlaVAAVL-FLGAL 389 Anaeromyxobac...
jgi:Tmz1t_1808 399 ALAAWRLGVLFVAAR 413 Thauera sp. MZ1T
Q7NUI7         398 SLWGGRFLPVYLRPR 412 Chromobacterium violaceum
WP_011803902   424 AVWGLRLIGWYGRLR 438 Acidovorax sp. JS42
EHR73511       422 GAWALRHGRWFGLPR 436 Burkholderiales bacterium JOSHI_001
jgi:Mpe_A1702  413 VGWALRYGRWMGRPR 427 Methylibium petroleiphilum PM1
jgi:Lcho_1485  415 LAWTRRHAAWFGRPR 429 Leptothrix cholodnii SP-6
WP_014236729   385 ALWVRRHGAMYLRPR 399 Azospira oryzae
WP_025308608   360 VVWAFVFIPKMISVr 374 Bdellovibrio bacteriovorus
Q6MK20         362 IVWGWLFLPKMIRVk 376 Bdellovibrio bacteriovorus
WP_012099098   390 ASWAALVLPALFpra 404 Anaeromyxobacter sp. Fw109-5
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