Conserved Protein Domain Family
Podoplanin

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pfam05808: Podoplanin 
Podoplanin
This family consists of several mammalian podoplanin like proteins which are thought to control specifically the unique shape of podocytes.
Statistics
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PSSM-Id: 399071
Aligned: 11 rows
Threshold Bit Score: 104.106
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_004741497  28 PEDDItvrpeddMTPAVENSMVTQG--VEDNVMTTGTSEDPYE-SGLTALVptnptNTESITDVRIEDGPTQESTV---- 100 domestic ferret
EHB11980      28 LEDNP-------VTSGATVARGTPG--KEDLIPTTSGSEAPRPsPRLTTQV-----SAESTTGPGVEDVSTLGSST---- 89  naked mole-rat
Q62011        28 NEDDI-------VTPGTGDGMVPPG--IEDKITTTGATGGLNEsTGKAPLVp---tQRERGTKPPLEELSTSATSD---- 91  house mouse
ELW68617      28 PEDDM-------VTPAAEDAMTAPG--AEDELVTTGASKEPYEfPGLTTPVs---tSVESVTDTYVEDLPTQESTV---- 91  Chinese tree shrew
Q95152        28 PDDIIpgvedsvVTPGTEDSVVTPG--AEDNVVTDGATEEPYE-SGLTPLVt---kNTESVTDLHLEDGPTQESTV---- 97  dog
4_pfamImport   1 PSTQE-------QTCLAGGRRTVPGclASPFCVTLGRSLDPHC-LALTTLLpt-ihSIGSKTEVRAQEK----------- 60 
XP_008273589  29 PEDEV-------VTPGVDGGTGLTG--VEDNVVTRGAREDHSEpHGVTALVp---tNAESVTSHHFEDHSFPHSTV---- 92  rabbit
Q402A0        28 PEDD--------VTTGVTSEKTTLG--VEDYTTTPAASKES--------LAtpmpaGTENVSHDHREDLPTAEGTTaegt 89  cattle
PNJ17189      28 PEDDI-------ETTGTEGGVAMPG--AEDDVVTPGASEDRYK-SGLTTLVa---tNVNSVTGIRIEDLPTSESTV---- 90  Sumatran orangutan
XP_011231081  28 PEDDI-----------------TPG--AEDNMVTAGTSVEPYE-SGLTAaVp---iNREGVTDLRLEDRAT-ESTV---- 79  giant panda
XP_010591406  28 PEDDI-------ITQGTEGGMVIPG--VEDNMVTVGASEKPPEsTDLATLVp---kSTDSTTHRHPEDLPTHESTGh--- 92  African savanna...
XP_004741497 101 -------HAKEESQSTTTvLNV-VTSH---------SIEKVGAEttvhTETTVEKDGLATVTLVGIIVGVLLAIGFVGGV 163 domestic ferret
EHB11980      90 -------QNHQKSQTTTT-PPM-ATNTstgkktsypKRVTVTES----TQTAVHKDGLSTASLAGIVIGVLITIGFLGGV 156 naked mole-rat
Q62011        92 -------HDHREHESTTT-VKV-VTSHsvdkktshpNRDNAGDE----TQTTDKKDGLPVVTLVGIIVGVLLAIGFVGGI 158 house mouse
ELW68617      92 -------HAQEESQSTTP-PNV-VTSQ---------S-----------------RDGLATVTLIGIIVGVLLAIGFIGGI 136 Chinese tree shrew
Q95152        98 -------HAKEESQSTTT-LNV-VTSH---------SREKVGED----TETTVEKDGLATVTLVGIIVGVLLAIGFIGGI 155 dog
4_pfamImport  61 -------MAPEVAKAGKTfLNA-STANea-----ssSSKKVGGE----TKTS-EKGGLETIALVGIILGIVITIGIIAGI 122
XP_008273589  93 -------PAHKESQKPTT-PNA-ATSR---------SMEKAGEE----PDTTIEKGGLATVTLVGIIVGVLLAIGFVGGI 150 rabbit
Q402A0        90 takstpaRSTPARSTTTVlTRVpATSH---------SQGKTDGE----KPKSTQKGGLSVGTLVGIIVGVLVGIAVIGGI 156 cattle
PNJ17189      91 -------HAQEQSPSATA-SNV-ATSH---------STEKVDGD----TQTTVEKDGLATVTLVGIIVGVLLAIGFIGGI 148 Sumatran orangutan
XP_011231081  80 -------RAEEETQSTTT-LNV-VTSHp---------tEKVGED----TETTVEKDGLATVTLVGIIVGVLLAIGFIGGI 137 giant panda
XP_010591406  93 -------HDHEKSQSTAA-PDV-ATGHs---------mEKMGGE----TQTTVEKDGLATATLIGIIIGVLVAIGLIGGI 150 African savanna...
XP_004741497 164 IIVVARKMS 172 domestic ferret
EHB11980     157 IFLFVWKMS 165 naked mole-rat
Q62011       159 FIVVMKKIS 167 house mouse
ELW68617     137 IIVVVRKMS 145 Chinese tree shrew
Q95152       156 IIVVARKMS 164 dog
4_pfamImport 123 VIAVVRKMS 131
XP_008273589 151 VIVVVRKMS 159 rabbit
Q402A0       157 ISVIVRKMg 165 cattle
PNJ17189     149 IVVVMRRMS 157 Sumatran orangutan
XP_011231081 138 IIVVVRKMS 146 giant panda
XP_010591406 151 IFVVVRKMS 159 African savanna elephant
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