Conserved Protein Domain Family
Cnd2

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pfam05786: Cnd2 
Condensin complex subunit 2
This family consists of several Barren protein homologs from several eukaryotic organisms. In Drosophila Barren (barr) is required for sister-chromatid segregation in mitosis. barr encodes a novel protein that is present in proliferating cells and has homologs in yeast and human. Mitotic defects in barr embryos become apparent during cycle 16, resulting in a loss of PNS and CNS neurons. Centromeres move apart at the metaphase-anaphase transition and Cyclin B is degraded, but sister chromatids remain connected, resulting in chromatin bridging. Barren protein localizes to chromatin throughout mitosis. Colocalization and biochemical experiments indicate that Barren associates with Topoisomerase II throughout mitosis and alters the activity of Topoisomerase II. It has been suggested that this association is required for proper chromosomal segregation by facilitating the decatenation of chromatids at anaphase. This family forms one of the three non-structural maintenance of chromosomes (SMC) subunits of the mitotic condensation complex along with Cnd1 and Cnd3.
Statistics
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PSSM-Id: 399062
Aligned: 52 rows
Threshold Bit Score: 454.936
Threshold Setting Gi: 281206008
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EPE03980             23 TLAQSPF--KnSP-VK----------IPLNDDASEKARRMHSRQA-LHEAQINQLKAAATPTSRKVsamrlddlengsps 88   Ophiost...
EDS36577              5 aavESPL--RrSDaSRlfrtpravstEEVNDDEAERRHRRSAASL-------DDSSVSG--------------------- 54   souther...
XP_001993141          4 praETPL--RrSAvGShresmlrdltTQVNDDEAERREARRRTLL-QNQARPRESMV----------------------- 57   Drosoph...
WGS:AANI:GJ17893-PA   4 prsETPL--RrSAvGShresmlrdltTMVNDDEAERREARRRTLL-QQQTRPRDSSV----------------------- 57   Drosoph...
WGS:AAPU:GI17284-PA   4 prsETPL--RrSAvGShresmlqdrtTMVNDDEAERREARRRTLL-LQQTRPRESTI----------------------- 57   Drosoph...
Q29KK3                4 prsETPL--RrSAvGSyresm-ardiTVINDDEAERREARRRTLL-VQQDTRKSSA------------------------ 55   Drosoph...
Q9VIP9                4 prlETPL--RrSAvGSyqegv-srmlTPFNDDEAERREARRRTLL---QQHHRSST------------------------ 53   fruit fly
XP_001962430          4 prsETPL--RrSAvGSyregm-ahntTVVNDDEAERQEARRRSMM-----QPRQST------------------------ 51   Drosoph...
XP_021331977         26 STTSTPLldN----------------IQGNDDEQERRQRRRSRVIdLHGVNDSSINEAGTHSSAGTpaa----------- 78   zebrafish
XP_008120019         38 SSSGTPVleN----------------FPDNDDERERKQRRRSRIV-DLQFSTDSSLPIQSPSNKHAetslp--------- 91   green a...
EPE03980             89 ssgsprtplsertprgrkrqslgpgvtskeaiaaaaaasgnraliddddddrvvvggsvvtpmkrvpiLAN------FEE 162  Ophiost...
EDS36577             55 --------------------------------------------------------------------GATvednenIKM 66   souther...
XP_001993141         58 --------------------------------------------------------------------LESieenetIRD 69   Drosoph...
WGS:AANI:GJ17893-PA  58 --------------------------------------------------------------------LESieenetIRK 69   Drosoph...
WGS:AAPU:GI17284-PA  58 --------------------------------------------------------------------LESieenetIKK 69   Drosoph...
Q29KK3               56 --------------------------------------------------------------------LESieenetIRS 67   Drosoph...
Q9VIP9               54 --------------------------------------------------------------------LESiednetIKN 65   fruit fly
XP_001962430         52 --------------------------------------------------------------------LESiedneaIRS 63   Drosoph...
XP_021331977         79 -----------------------------------------------------------------vpkLSSaqisehYST 93   zebrafish
XP_008120019         92 ----------------------------------------------------------------aipqLSNaqiadhYST 107  green a...
EPE03980            163 WMKMATDNKINATNSWNFALIDYFHDMslLKEGDG--VNFQKASCTLDGCVKIYTSRVDSVATETGKLLSGLADSRE-KK 239  Ophiost...
EDS36577             67 CLQLYSDNKLSKDNAWSVTIIDAFSKL--MSRHSSslHNFQVAGSTLEASTKVYGLRVDSVHTDVMRMCSELTRQSArTM 144  souther...
XP_001993141         70 CLAIYNGNKLSRDNAWNLSLIDTLSSL--LDRHHKtlSNFKMAGSSLEASSKVYGLRVDSIYLDAMRMAAGLSARTLtEQ 147  Drosoph...
WGS:AANI:GJ17893-PA  70 CLEIYNGNKLSRDNAWSLSLIDTLSSL--LDRHHKtlSNFKMAGSSLEASSKVYGLRVDSIYLDAMRMSAGLSARTLtEK 147  Drosoph...
WGS:AAPU:GI17284-PA  70 CLEIYNGNKLSRENAWSLSLIDTLSNL--LDHHHKtlSNFKIAGSSLEASSKVYGLRVDSIYLDAMRMSAGLNARTLtQQ 147  Drosoph...
Q29KK3               68 CVDLYNCNKLSKDNAWHMSLIDSLATL--MDRHHKklSNFKMAGSSLEASSKVYGLRVDSIYIDAMRISAGLSARTLtDK 145  Drosoph...
Q9VIP9               66 CLELYNGNKVSKDNAWNLMLIDSLANL--LDHHHKrmSNFKMAGSSLEASSKVYGLRVDSIYLDAMRISAGLSARTLtDK 143  fruit fly
XP_001962430         64 CLEIYNGNKLSKDNAWSVSLIDSLANL--LDHHHKrmSNFKMAGSSLEASSKVYGLRVDSIYLDAMRISAGLSARTLtDK 141  Drosoph...
XP_021331977         94 CIKLSTENKITTKNAFGLHLIDYMADI--LKEKDSe-LNFKVAAGTLDASTKIYAVRVDAVHADAYRVLGGLGSET---- 166  zebrafish
XP_008120019        108 CIKLSSENKITTKNAFGLFLIDYMAEI--LKQKDSelTNFKVAAGTLDASAKIYAVRVDAVHADVYKVLGRLGKESEpAG 185  green a...
EPE03980            240 K--------GGSGNgEGEDSEDDeLDEDGNVK------KKT-KKKQRS-EATLAPSFASLQLKKLELEFAVDPLFKKASA 303  Ophiost...
EDS36577            145 DnnrdggedEDDEDgGANKENDTtVGGGGGEAgggatqEKVkKKRARKhVSTITKNKETIN-AALDTNPFTDPFFAKLNS 223  souther...
XP_001993141        148 Qlna---aaDRDDSiAGNAEGg--SADDIEPAqa---aAPKpKKRTRK--ATVTKNKDTLN-ARLDTAPLQDPVFGKLNS 216  Drosoph...
WGS:AANI:GJ17893-PA 148 Qlna---aaDRDESiAEQAEDg--AADGIEAApg---aAPKaKKRTRKpVSTVTKNKETLN-ARLDTAPLQDPVFGKLNS 218  Drosoph...
WGS:AAPU:GI17284-PA 148 Qlnaa-aadDNDDSaNVGQVEg--GGDGVIDAse--taAPKaKKRKRKaVSTITKNKETLN-ARLDTAPLQDPVFGKLNS 221  Drosoph...
Q29KK3              146 Qin----daDADDEgLPEGPPGDgEGGDAAPSqqq-qaAPK-PKRQKRnLSTVTKNKETLN-ARLDMVPMQDAVFGKLNS 218  Drosoph...
Q9VIP9              144 Qin----aaEDDDGpQGEQATg--EGQDSAQQaak-eaAPK-PKRQKKpISTVTKNRETLN-SRLDTAPLQDPVFGKLNS 214  fruit fly
XP_001962430        142 Qin----aaENDDGtEPSQAGg--EGDDSASAssqkaaAPK-PKRQKKnVSTVTKNKETLN-ARLDTTPLQDPVFGQLNS 213  Drosoph...
XP_021331977        167 ---------KPKESqDGDDETEAaEGSQGEQV------AAKqTKKRPPkK-TVEQNLSNINLSESEMKCEVDPMFQRMAA 230  zebrafish
XP_008120019        186 Ptn-----gQDTGEaDGDLESS----------------KKNtRKRKRLyK-TIEKNLNNINASETDRRVGIDPMFQQTVA 243  green a...
EPE03980            304 DFDEGGAKGLLL-NHLMI-DGQGRI-----VFDSSDDANDIAksskkngkgkkstqdgeeadeddeadededdadvdgeg 376  Ophiost...
EDS36577            224 VVGDVNSSSRLMqNIVPTrDAELLLrmdynFWDDSEAPE----------------------------------------- 262  souther...
XP_001993141        217 TVGSINASNRLMhNVLPTlDSELRLrtnyvFWNSEELPTEVK-------------------------------------- 258  Drosoph...
WGS:AANI:GJ17893-PA 219 TVGSINASNRLMhNILPTvDSELRLrtnyrFWQDQKLPEEVQ-------------------------------------- 260  Drosoph...
WGS:AAPU:GI17284-PA 222 TVGSINASNRLMnNILPTkDSELRLrtnyrFWQNPNMEEKIE-------------------------------------- 263  Drosoph...
Q29KK3              219 TVGSINASNRLMhNILPSvDSEMRLrtthkFWDSTEETDELM-------------------------------------- 260  Drosoph...
Q9VIP9              215 TVGSINASNRLMhNILPSfDSELRLrttynFWNSEESTEEVQ-------------------------------------- 256  fruit fly
XP_001962430        214 TVGSINASNRLMhNILPSrDSELRLrtnykFWDGEEVSEDIQ-------------------------------------- 255  Drosoph...
XP_021331977        231 SFDENSTAGVFL-SVLFSeDSCCEL-----RFPS---------------------------------------------- 258  zebrafish
XP_008120019        244 SFDECSTAGVFL-TTLRThSDLSEA-----LFDSm--------------------------------------------- 272  green a...
EPE03980            377 adtsRHASVEPE-DEQDMPVDVVSLGH-------------RFFPELHR--LEE-LDVCPSLKTFDLGN---PSGSLDIPF 436  Ophiost...
EDS36577            263 ------------------------LELeveetydncelttATMFNVNR----QsHKLHTMLAGYVITDapaED------- 307  souther...
XP_001993141        259 --------------------DYISVDPeiknldtqslvsaEWAIKLRRy-DQQ-LMLRPLHSGYIITDapnPTNANEQPT 316  Drosoph...
WGS:AANI:GJ17893-PA 261 --------------------DYTIVDSdiknldtqtlvsaEWAKKLRRy-DQQ-LKLRPLHTGYIITDapnPINAND-PA 317  Drosoph...
WGS:AAPU:GI17284-PA 264 --------------------DYTLVNNddknth--tiiaaEWVNKMRRy-YQQhLVLRPLHTGYIISDvpnPSNANDPMQ 320  Drosoph...
Q29KK3              261 --------------------DSETLSAstkewtneelcnaDWLPKLYNh-MDK-LNLRPLHTGYVITSapnPKPQTGSIS 318  Drosoph...
Q9VIP9              257 --------------------DHTTLNAemeqwpatslmstNLMRKLLPh-AER-SNLRPLHTGYIITSapnPKSANEKAA 314  fruit fly
XP_001962430        256 --------------------DHTTLFAekqqwpteslvsaDWLRKLLPq-VDK-LNLRPMHTGYIITSapnPKPSAEKPK 313  Drosoph...
XP_021331977        259 --------------------HMTLLKSqlppvqvshqnvpASPFTGHLktLED-RPICPSLEDFSFTRwtpEQ-TTNLNQ 316  zebrafish
XP_008120019        273 ---vTPLSSVASeAPHSSAVKMAGLRAvll------------------qcAEK-RPLCPSLAGFRFSEwdsASHNESVSA 330  green a...
EPE03980            437 LKALE---QdgqDGAG---------GEksALYIDEDNPLGFD------DTD-A-LGGFDLG------G--D---VNFGEG 485  Ophiost...
EDS36577            308 --------D---------------------------------------DDDdAiNHLKDIQdarvrdAedDlhpNNRSAL 340  souther...
XP_001993141        317 ADQLP---E---------------------------------------DDDfGvDNADDFH-------------DNPKEL 341  Drosoph...
WGS:AANI:GJ17893-PA 318 AANST---D---------------------------------------NNDmGvDNADDFY-------------ENPREL 342  Drosoph...
WGS:AAPU:GI17284-PA 321 IK----------------------------------------------DDDdGvDNADDFY-------------ENPREL 341  Drosoph...
Q29KK3              319 EAAPTy--D---------------------------------------DDDeGlDNADDFG-------------VNPTDI 344  Drosoph...
Q9VIP9              315 EVVQD---E---------------------------------------DHDeGlDNADDMC---------------VNEI 337  fruit fly
XP_001962430        314 EPEAEappE---------------------------------------EEDdGvDNADDMC-------------ANINEI 341  Drosoph...
XP_021331977        317 LLEKMkqgE---HAFDvnadiepdeDD--APDFGDNFDADVDeg--rpGDNeEfKEHKEACsks-pqNgrGvipIGEVDI 388  zebrafish
XP_008120019        331 LLEKFkksN---QVFDinaevdsdpGD---PLMEDDFDAD-NmdntvaNDLgEfSENIEACrtaprnSkkNavlLGEGDV 403  green a...
EPE03980            486 GEAWAREARLEPQmrvydagGLdG-----DVVD--Dlllgpg---tgaptdDF-TIAMPH-AQQSDKL-HD--NILS--- 547  Ophiost...
EDS36577            341 EVQFDIDAEVEPIpv----gDAyi----iDYASadAmgdggadnddefneeDHlALQNCRgLKRKTVViEDmrPIDSssi 412  souther...
XP_001993141        342 SMAFDINAECEPMpq----lDE-PesnilPVDYneEleel--------tpeELlALNRCRaLRNKPVVvEDlrPVDGrsk 408  Drosoph...
WGS:AANI:GJ17893-PA 343 SMAFDINAECEPIpe----lDA-PaatvlEVDYn-Eleel--------tteERtTLQHCRaLRKQTVLiEDlrPVDGssk 408  Drosoph...
WGS:AAPU:GI17284-PA 342 SMAFDINAECEPMpd----lNAlTaatvlEMDYn-Emdel--------tteERtTLQHCRvLRKQPVLiEDlrPVDGssk 408  Drosoph...
Q29KK3              345 SVAFDMNAECEPMpd----mEA-GppiilEIQSn-Dlqel--------taeEQtVVNNCRrLRKTAEFiDDlrPVDGvtr 410  Drosoph...
Q9VIP9              338 SMAFDINAECEPMpd----lDG-PpplvlEVDSn-Eleel--------taeEQmVINNCRrLRKQTEFiEDlrPVDGnsk 403  fruit fly
XP_001962430        342 SMAFDVEADVAPMpd----lDA-AppqvlEVGGd-Dlqel--------tmeEQmVIHNCRrLRKQATViDDlrPVDGssk 407  Drosoph...
XP_021331977        389 ---------------------------------------------------------------------ATmcLQLSdqp 399  zebrafish
XP_008120019        404 ---------------------------------------------------------------------SSmcLQLSmnp 414  green a...
EPE03980            548 ----YFDQALR--KNWVSAEHWRIRKI--K----------DVNKPAT---------AA-KPR--KEKEPFAIDFGAPLEt 597  Ophiost...
EDS36577            413 nleySYRALDNisQFWAGPSHWKFKRSkgPsslrfstvs--------ggaagpdgkTTkGKPttRKKKRFDEHVIDDII- 483  souther...
XP_001993141        409 -leySYRPMDKisQFWAGPSHWKFKRMraRstigqsnaldNNSAGGNsgataaatrARrAALlaAKRRSKQLNFG----- 482  Drosoph...
WGS:AANI:GJ17893-PA 409 -leySYRPMDQisQFWAGPSHWKFKRIraRstlghtnaqdNIAASGsggta-aaarIRrAALqaAKRRSKQLNFG----- 481  Drosoph...
WGS:AAPU:GI17284-PA 409 -leySYRPMDQisQFWAGPSHWKFKRTrnTntfaqitsqdNVTGkstna---aaarLRrAAAqaAKRRSKQINFG----- 479  Drosoph...
Q29KK3              411 -ldySYRPMEQisQFWAGPAHWKFRRTrpRttlaqsngpmDAvta---------akPKkTAAaaAKRRMKEVQYG----- 475  Drosoph...
Q9VIP9              404 -leySYRPMDQisQFWAGPSHWKFKRTrpRstfsqtngqvDTQPirt-------qrAKkSAHlnANRRAKALDYG----- 470  fruit fly
XP_001962430        408 -leySYRPMEQisQFWAGPSHWKFKKNraRstlfqtngqtDTQVgsi-------qrPKkSAQqaAKRKNKLIAYG----- 474  Drosoph...
XP_021331977        400 reysYFSPRTM--ATWVGPGYWLFKPGhkQdqk---------------------pdKEpRKR--APKNPLIIDFKADIN- 453  zebrafish
XP_008120019        415 seysYFSPRTM--SMWRGPEHWRFKLRqqSean---------------------teKAsKRK--APRKAFEISFEEEVD- 468  green a...
EPE03980            598 SMAELLFTQ----ASSNTAILLPKKDWKAKSRN---LLPDDKHFHSKQLLSLFLKPKARLSRRrqqfgafgslfgqnqqp 670  Ophiost...
EDS36577            484 SVEEDLFVAynplRPTIKNITHQKSMICKKWDSkklKLPTDYHLERNRFDVNAYARGLKVRDF----------------- 546  souther...
XP_001993141        483 VYTESLF------QTLDANTKLRKANFQKRWDArklMLPTKFDFEPNYFYKYDYAPSIKVSRR----------------- 539  Drosoph...
WGS:AANI:GJ17893-PA 482 QCTENLF------QALDSNTKLRKANYQKRWDArklMLPTKFEFEPNYFYRYDYAPSIKVSRR----------------- 538  Drosoph...
WGS:AAPU:GI17284-PA 480 QCTESLF-------KLDESTKLRKANYQKRWDPrklRLPTKYDFDANYFYKYDYAPSIKVSRR----------------- 535  Drosoph...
Q29KK3              476 KFKEEFF------QPLDANIKQRKVNYQKKWDArklVLPTKFNFEADYFFKYDSAPSIKVSQR----------------- 532  Drosoph...
Q9VIP9              471 NVTENFF------QQLDTTIRQRKANFQKKWDPrklILPTKFELDPDLFFKYESAPSIKLSKR----------------- 527  fruit fly
XP_001962430        475 KVTQDFF------QPLDASVKQRKVNFQKKWDArklSLPTKFNFDWDYFFKYDSAPSIKLTRR----------------- 531  Drosoph...
XP_021331977        454 --FHNYF------KTTRAATTISKSALNTSNKKt--TLPADFQYPPSNLSQLNLKPSNTLSAEgkk-------------- 509  zebrafish
XP_008120019        469 --FEPYF------RKTRAATTLAKSTLENQNKKg-yTLPADFHYDPDNLTGLFLKPGHRLCKMpqq-------------- 525  green a...
EPE03980            671 savpegemdeafwasqkdplrqtvedgngsgrdGE---P-HGDYDANFFA-DDGL-PF--AG-G-------DDDDGDiD- 733  Ophiost...
EDS36577            547 ----------------------------------------DAAPEPDLPVdDEYDyGNpvDQnYcsrneagDDD------ 580  souther...
XP_001993141        540 ----------------------------------------FGVQDDd----DG---EMyiDTnAaaddvadDVELFD--- 569  Drosoph...
WGS:AANI:GJ17893-PA 539 ----------------------------------------YGVQDDd----ED---DMdrDTnTaaddaadDVELFD--- 568  Drosoph...
WGS:AAPU:GI17284-PA 536 ----------------------------------------FGVPDDDIDNdDD---VMgrDMnAvgddagdDVDLFD--- 569  Drosoph...
Q29KK3              533 ----------------------------------------FGEADLd----EGMGnDMdmDGgShhg--daDIELFD--- 563  Drosoph...
Q9VIP9              528 ----------------------------------------AGEPDSd----EGGDlGIdmDAdMhhd-ddnDQELFN--- 559  fruit fly
XP_001962430        532 ----------------------------------------AGEPDSd----DADDlGLdmDAgSehgdvenDLDLLG--- 564  Drosoph...
XP_021331977        510 -------------------------------rlSGelsEdIGEYNYNNANdTANFcPGlqEGdSedaegfaGSDDSQtDr 558  zebrafish
XP_008120019        526 -------------------------------gtSPsrdDeAGEYDYNNPNdTSNFcPAl-----------qDVDSDDdDi 563  green a...
EPE03980            734 Ee--FADA------------RDHFSPvdgagln--ntvdvggMTQG-FTQ--GFTQGFTtgfggLTVTNPAD------LA 788  Ophiost...
EDS36577            581 --------------------AEHQGA----------------GGFGdAAAddHHTFDDLagpasVSGGGTTln---tsLD 621  souther...
XP_001993141        570 --------------------NDHFDAdtpqspthmnvstmqgTSVGgDNGdtFLDTESAa----aQGNATLRhcn-dtVL 624  Drosoph...
WGS:AANI:GJ17893-PA 569 --------------------NDHFEPdtphspg---emsvstmNLGgEPGatIMGGEQAtcgnlNQGNATMRnncndtVL 625  Drosoph...
WGS:AAPU:GI17284-PA 570 --------------------NDEFQRssdrlpn--dmnvssfPNADpALAsfRLSDDPNa--------cNDRtqandtVL 619  Drosoph...
Q29KK3              564 --------------------NEHFTTddp-----------vmNRMSgAGIedPMDMMNVdvcegMPSQSQSMhvgqdtIV 612  Drosoph...
Q9VIP9              560 --------------------NEHFTDavpanv-----sviaaIAAEqAAEasMMNVSAGe-----iGLTQMNatcnntVF 609  fruit fly
XP_001962430        565 --------------------NEHFTAavpan-------vsimLPVEgAEGadGLDMDARdatlgL-TNVSMRdpcnntVL 616  Drosoph...
XP_021331977        559 PtpfSLDTdd------------------------------------------------------------------isTY 572  zebrafish
XP_008120019        564 PavfVGQGgmfemtahpitmANQDGE-----------------------------------------LHGAInglditTY 602  green a...
EPE03980            789 FGTTLVTS-SRRVRPEYVQYARVAKRVDVRRLKEELWKGMPFDKG-----------VAASRLLtpppttaedeaggaasi 856  Ophiost...
EDS36577            622 FIPTEFQGaPDKVAKINIAYAKTAKVVDMKQLKSCCWRLITEQVCatqatpseegdDTTTASE----------------- 684  souther...
XP_001993141        625 EISTEFEGaPTQVTKVIVPFAKRAKVIDMKNLKRSCNSLIQKQLLnavdd--ekipTHPKANQe---------------- 686  Drosoph...
WGS:AANI:GJ17893-PA 626 EIATDFEGaPTQVTKVIVPFAKRAKVIDMKNLKRSCNSLIQKQLLtnatieekkipAHAKAKEe---------------- 689  Drosoph...
WGS:AAPU:GI17284-PA 620 EISTEFQGaPSQVTKVIVPFAKRAKVIDMKNLKRSCNSLIQKQLLstaemeeeaipAHPKGKQe---------------- 683  Drosoph...
Q29KK3              613 EIATEYEGaPKQVTKVIVPFARRAKVIDMKNLKKNCNSLIQKQLLspvde--asipSHPVPKEe---------------- 674  Drosoph...
Q9VIP9              610 EIGTEFEGaPSQVAKVIVPFAKRAKVIDMKNLKKSCNSLIQKQLLnavpe--etipSHPKKKGe---------------- 671  fruit fly
XP_001962430        617 EIGTEFEGaPSQVTKVIVPFAKRAKVIDMKNLKKSCNSLIQQQMLsavpe--etipSHPRPKKe---------------- 678  Drosoph...
XP_021331977        573 GEDCLVPE-PHKLNIIEINYARTAKKMDMKKLKTTMWGLLTESPEktakqvesedtT----------------------- 628  zebrafish
XP_008120019        603 AESNLVAE-PQKVNKMEIQYAKVAKKMDMKRLKQTMWRLLTYVPKdqteeenesleKSTGCSV----------------- 664  green a...
EPE03980            857 daqleksfaepgegsgggkgsEDDRMLKFTDVMNGLQAVYNKSMMDDISTSYCFISLLHLANEKGLQISKTEDLRDLDIR 936  Ophiost...
EDS36577            685 ---------------------AHSGKARFSEIYRELPHILSKTMSENISKSLAFYSVLHLSNERSLRLVRQDDLEDFQIL 743  souther...
XP_001993141        687 --------------------hYAKGMATFKGVYNELPNLLTQKMAESLSPSVAFYAVLHLANDMKLRLLQQDDLENVIIR 746  Drosoph...
WGS:AANI:GJ17893-PA 690 --------------------hYAKGMATFKEVYDKLPSVLSAKMADSLSPSVALYAVLHLANDMRLRLIPQDDFENFTIR 749  Drosoph...
WGS:AAPU:GI17284-PA 684 --------------------hYAKGMATFKEIYEKLPAMLTTKMSDSLSPSVALYAVLHLANDMRLRLIPQDDFEDFTIR 743  Drosoph...
Q29KK3              675 --------------------sYAKGTASFQELYRTLPDMLNAKMKDSLSPSVALYAVLHLANDMKLRLIPQENLEDFKIR 734  Drosoph...
Q9VIP9              672 --------------------hYSKGFASFQQVYQKLPDLLTTKMSDSLSPSVAFYAVLHLANDLKLRLIPQEDLEDFQIR 731  fruit fly
XP_001962430        679 --------------------qYSKGVASFQDVYCKLPNLLTTKMSDSLSTSVAFYAVLHLANDMKLRLIPQEDLEDFKIR 738  Drosoph...
XP_021331977        629 ---------------------EVPGEKSFSQSIRNLVQRLPSAMATNLSVPLAFVALLHLANEKNLELHKIDGMTDIIIK 687  zebrafish
XP_008120019        665 ----------------------VSEEKIFSSITKDLLHRLPPTMAKNLSVPLAFASLLHLANEKNLKLKGLEDLSDVLVT 722  green a...
EPE03980            937 K 937  Ophiostoma piceae UAMH 11346
EDS36577            744 a 744  southern house mosquito
XP_001993141        747 Q 747  Drosophila grimshawi
WGS:AANI:GJ17893-PA 750 Q 750  Drosophila virilis
WGS:AAPU:GI17284-PA 744 Q 744  Drosophila mojavensis
Q29KK3              735 Q 735  Drosophila pseudoobscura
Q9VIP9              732 Q 732  fruit fly
XP_001962430        739 Q 739  Drosophila ananassae
XP_021331977        688 Q 688  zebrafish
XP_008120019        723 Q 723  green anole
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