Conserved Protein Domain Family
VWA_CoxE

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pfam05762: VWA_CoxE 
VWA domain containing CoxE-like protein
This family is annotated by SMART as containing a VWA (von Willebrand factor type A) domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria.
Statistics
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PSSM-Id: 399053
Aligned: 12 rows
Threshold Bit Score: 168.724
Threshold Setting Gi: 81545780
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O53703        171 LGAWLEA----TMARWPRRRsmr-feSSPHGKRIDLRATMNASRSTGWE---------SVLLARIRp-R-RRPRRVLLLC 234  Mycobacterium...
Q9Y9R7        129 LYRSLALlrrrLGLEEGRRR------VPRRRGRIDFKRSMRRSLRTFGE---------TVRLVRAS--RkRSKTDILVLL 191  Aeropyrum pernix
Q9KX26        168 AAHAVAA----RLAKAMRVRltrreqSRRTGRRIDLRRTIHKNIAHGGM---------PLELVWRQ--RkHKPLRLVVLL 232  Oligotropha c...
Q9XAH6        941 LATRLRP----TLTGLTTPRp-----TRRPGGPLDLPRTLRANLAHIRRredgrvevvPERPVFRTrtArRNDWRLILVV 1011 Streptomyces ...
Q9RJY6       1094 LATRLRP----ALHGTVVPRp-----SRRPGGGLDLPRTLRANLASAHRgpdgtvrvlPEHPVFRTraRrSADWRLVLVT 1164 Streptomyces ...
Q9KY59        149 LVTRTRA----TLSGALDRSar---tARPRPHDIDWNRTIGANLKHYLPeyrtvvperLVGYGRAS--RsVRK-DIVLCV 218  Streptomyces ...
P33352        151 LAKEVRQ----AFSGVRDRRrr---sFIPLARNFDFKSTLRANLQHWHPqhgklyiesPRFNSRIK--RqSEQWQLVLLV 221  Escherichia c...
O27843        123 LGIKIAN-----------RRsr--rlRQSRRMKPDIRRSIRKNIKHGGT---------VLELIRSEp-ReRKS-QHIFLS 178  Methanothermo...
P71923        252 MRRVVAPlartLATRLAARR------RRARAGSIDLRKTLRKSMSTGGV---------PIDLVLHKp-RpARP-ELVVLC 314  Mycobacterium...
Q8XZD6        161 LQHMIRR----RRVHLAQERtrr-lkAASRGRHPDLRATARQAVRAGGE---------WTAWKYRQp-VdRTP-PLVLLL 224  Ralstonia sol...
Q92PJ9        163 ARKALSA----ILLPLDRVRtrr-yrRSHRPVRIDPRSTMRDAMRFGGD---------FILPRFREp-RlVHP-PLVVLA 226  Sinorhizobium...
WP_011088408  179 alRAVER----MRLPQAELLtrr-hrPDSRGLRLDLRRTLRASLRTGGD---------IIDIHRLG--RiEKPAPIVALL 242  Bradyrhizobiu...
O53703        235 DVSRSMQPYAAIYLRLMRAAVLRRAggHPEVFAFSTSLTRLTSVL-SHRSAEMALHRA--NARVTD-RYGGTFIGRSVAA 310  Mycobacterium...
Q9Y9R7        192 DVSNSMKDYWPWILGILNALRRLPPg-SYEAFLFSTRLVRATPMV-EAAGGAEDLRRL--LSRVEGlWGSGTRISQSVEE 267  Aeropyrum pernix
Q9KX26        233 DASGSMSMYSAVFLRFMHGILDNFR--EAEAFVFHTRLIHISPAL-RERDATRSVERM--SLLAQG-VGGGTRIGESLAT 306  Oligotropha c...
Q9XAH6       1012 DVSASMET-SVVWSALTAAILGGAPtlSTHFLTFSTQVADLTGLV-A--DPLSLLLEV--K------VGGGTHIAAGLAH 1079 Streptomyces ...
Q9RJY6       1165 DVSGSMEA-STVWAALTASVLAGVPtlSTHFLAFSTEVIDLTDHV-D--DPLSLLLEV--S------VGGGTHIAAGLRH 1232 Streptomyces ...
Q9KY59        219 DQSGSMAA-SLVYASVFGAVLASMRsiDTRLVVFDTAVADLTDQL-D--DPVDVLFGT--R------LGGGTDINRALAY 286  Streptomyces ...
P33352        222 DQSGSMVD-SVIHSAVMAACLWQLPgiRTHLVAFDTSVVDLTADV-A--DPVELLMKV--Q------LGGGTNIASAVEY 289  Escherichia c...
O27843        179 DVSGSCDWISNWFFCIIYAAQRTFY--RSRFFDFDSRIVETTHLL-DEDDLYDAFRNLreSRIRNLmIHGTSNMYTAFRD 255  Methanothermo...
P71923        315 DVSGSVAGFSHFTLLLVHALRQQFS--RVRVFAFIDSTDEVTHMFgPESDLAIAIQRItrEAGVYA-RDGHSDYGNAFVS 391  Mycobacterium...
Q8XZD6        225 DISGSMSRYSRAVLYYCHALAQSRE--RIQAFLFGTRLTSVSRQL-RERDPDVAVQAI--AQQVPD-WSGGTRIGAALAE 298  Ralstonia sol...
Q92PJ9        227 DISGSMSKYTRIFLHFLHALTEQRH--RVHTFLFGTRLTNVTRQM-RNRDPDEALDDC--IAAVKD-WSGGTRIGETLHD 300  Sinorhizobium...
WP_011088408  243 DISGSMNEYTRLFLHFLHAIGDARK--RVSVFLFGTRLTNVTRAL-RQRDPDEALASC--SASVED-WAGGTRISASLHN 316  Bradyrhizobiu...
O53703        311 LLAPPHgNAL-RGAVVIIASD-----GWDSDPPDVLVHALTRVRRRAELLVWLNPR--AAHPEFQPRa-gSMAAALPYCD 381  Mycobacterium...
Q9Y9R7        268 LLESHT-PALhRGAAVLVFSD-----GWDLGDLGRLASALAELRRRAGFLVWVTPEspRRDAGGEPS---TMRIIRRHAD 338  Aeropyrum pernix
Q9KX26        307 FNRWHAkRAIhSRTCVMIVSD-----GYDTGPAEQLEREMSALRRRCRRIAWLNPM--IGWRGYAPEa-aGMKAALPHVD 378  Oligotropha c...
Q9XAH6       1080 ARSLVTvPD---RTLVVVVSD-----FEEGAAVEGLLAEVGALVSAGVRLLGCAAPadGGTPRYSVPvtrRLVAAGMPVA 1151 Streptomyces ...
Q9RJY6       1233 ARELVTvPS---RTLVVVVSD-----FEEGYPLGGLLAEVRALVGAGCHVLGCASLddAGRPRYSTGvagRLVAAGMPVA 1304 Streptomyces ...
Q9KY59        287 CQSRITrPA---DTVVVLISD-----LYEGGIREEMLKRVAAMRVAGVRFVTLLALsdEGTPAYDREhaaALAALGAPAF 358  Streptomyces ...
P33352        290 GRQLIEqPA---KSVIILVSD-----FYEGGSSSLLTHQVKKCVQSGIKVLGLAALdsTATPCYDRDtaqALVNVGAQIA 361  Escherichia c...
O27843        256 FIEGVTfTG---KSYIVILSDcrdwaGPRRDGIPESVELVAEMSERARKVLILNPEpeKKWDVVDSCv-sLYRDAGASVM 331  Methanothermo...
P71923        392 FMQGFP-NVLsPRSSLLVLGD-----G-RTNYRNPATDVLADMVTASRHAHWLNPEpkHLWGSGDSAvprYQEVITMH-- 462  Mycobacterium...
Q8XZD6        299 FNRRWArRTLsGRATVLLVTD-----GLDHEHIDLLDAEMARLARFAHRIVWLNPL--LRFAGFEPRa-rGVRAILPHVD 370  Ralstonia sol...
Q92PJ9        301 FNRRWSrRVLgQGAVVLLMTD-----GLERDDTAELETEIDRLHRSCRRLVWLNPL--LRFDGFEARa-rGVRAMLPHVD 372  Sinorhizobium...
WP_011088408  317 FNKLWArRVLsQGAIVLLISD-----GLEREADSRLAFEMDRLHRSCRRLIWLNPL--LRFGGFEAKa-qGIKMMLPHVD 388  Bradyrhizobiu...
O53703        382 LFLPAHSLAGL 392  Mycobacterium tuberculosis
Q9Y9R7        339 LTIDLETLLNT 349  Aeropyrum pernix
Q9KX26        379 LFAPAHNLESL 389  Oligotropha carboxidovorans
Q9XAH6       1152 ALGPLSLARWV 1162 Streptomyces coelicolor
Q9RJY6       1305 ALSPLELARWV 1315 Streptomyces coelicolor
Q9KY59        359 ACTPDLFPEVM 369  Streptomyces coelicolor
P33352        362 AMTPGELASWL 372  Escherichia coli K-12
O27843        332 EVRTLRQLAEV 342  Methanothermobacter thermautotrophicus str. Delta H
P71923        463 ECRSAKQLATV 473  Mycobacterium tuberculosis
Q8XZD6        371 TMVPAHHFDSL 381  Ralstonia solanacearum
Q92PJ9        373 EFRPIHNLESV 383  Sinorhizobium meliloti
WP_011088408  389 EFRPVHNLSSi 399  Bradyrhizobium diazoefficiens
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