4OHF


Conserved Protein Domain Family
5_nucleotid

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pfam05761: 5_nucleotid 
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5' nucleotidase family
This family of eukaryotic proteins includes 5' nucleotidase enzymes, such as purine 5'-nucleotidase EC:3.1.3.5.
Statistics
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PSSM-Id: 399052
Aligned: 91 rows
Threshold Bit Score: 461.21
Threshold Setting Gi: 300265603
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4OHF_D        14 MRKIKLIGLDMDHTLIRYNsKNFESLVYDLVKERLAESFHYPEEIKKFKFNFDDAIRGLVIDSKNGNILKLSRYGAIR-- 91  Legionella pneu...
EEB19928      81 LKEISVYGFDYDYTLACYK-PSLDLLIFNLGKEALVNKFMYPKDVLNLKYNPDFTIRGLHYDIEKGLFVKLDSFLQIQlg 159 human body louse
XP_002595182  28 MGDVEVYGFDYDYTLAHYT-DELYPLIYNLAKERLLMRNKYPESIMALEYIPGFAVRGLHYDIEKALLMKIDAFHHIQlg 106 Florida lancelet
XP_005796446 114 LRDIEIYGFDYDYTLAFYS-SHLHTLIFDIARDILINNHRYPEDLRKYEYIPDFAVRGLHYDVQKALLMKIDAFHYIQlg 192 southern platyfish
XP_003269986  93 LSDIEIYGFDYDYTLVFYS-KHLHTLIFNAARDLLINEHRYPAEIRKYEYDPNFAIRGLHYDVQRAVLMKIDAFHYIQlg 171 northern white-...
XP_014348827 116 LSDIEVYGFDYDYTLAFYS-KDLHTMIFNIARNILIDQLRYPEELRTYEYSPNFAIRGLHYDVQTALLMKIDAFHYIQlg 194 coelacanth
XP_005801814 150 LEEVDIYGFDYDYTLAQYS-NALNALIYDTAKGFLIEHFKYPEEIAKYEYIPNFTVRGLHYDIQKGLLMKIDAFHYIEpg 228 southern platyfish
XP_008102124 105 LNTIEVYGFDYDYTLALYS-PALHSRIYNTARDILVEQYKYPKGILEYEYWPTFAIRGLHYDIAKGLLMKIDAFHYIQlg 183 green anole
KAE8612924    71 LAEIEIYGFDYDYTLAQYS-DALHHMIFSTARDLLIQHYRYPEGIGRYEYIPGFAIRGLHYDIQKSLLMKIDAFHYVQlg 149 tropical clawed...
XP_014344299 130 LGDIEIYGFDYDYTLAQYS-NSLHTMIFNTARDILVDQYRYPEDIKKHKYAPGFAIRGLHYDIQKSLLMKIDAFHYVQsg 208 coelacanth
4OHF_D        92 LSYHGTKQISFSDQKKIYRSIyvdl-----------gdpNYMAIDTSFSIAFCILYGQLVDLKDTnpDKMPSYQAIAQDV 160 Legionella pneu...
EEB19928     160 TVYKGLRRVPDEEVIQLYKNKviplafveakdkigsgrtKLYQLADIFSRPEMSLLCCIVDYFDAk-GFDYHPEIVFRDV 238 human body louse
XP_002595182 107 TVFRGHQQVSDAEVFSQYDGThvpvdymssfhgrvsmgkQMVQLMDMFSLSEMALLCDITEFFLKn-GIEYDPEYLFYDV 185 Florida lancelet
XP_005796446 193 TVYRGLHPMPDEEVIAMYEGShvpleimsdfygksihghTMKQFMDIFSLPEMTLLSCVNDFFMRh-NIDYEPVHLYKDV 271 southern platyfish
XP_003269986 172 TVYRGLSVVPDEEVIEMYEGShvpleqmsdfygksshgnTMKQFMDIFSLPEMTLLSCVNEYFLKn-NIDYEPVHLYKDV 250 northern white-...
XP_014348827 195 SVYRGLNTVPDEEVIAIYEGShvpleqmsdfygksshgnTMKQFMDIFSLPEVTLLSCVNDYFITn-NIDYEPVHLYKDV 273 coelacanth
XP_005801814 229 TVYRGLSPVSDDEVLYLYGGTfhvplsqd--sgfygkgpKVKQFMDIFSIPEMTLLAVANDFFITn-DIEYDPVHLFKDV 305 southern platyfish
XP_008102124 184 TVYRGLKPVPDDEVLEMYDGThhiplhqa--sgfygkgpAIKQFMDIFSLPEMTLLAVANDFFISn-DIDYDPIHLYKDV 260 green anole
KAE8612924   150 TAYRGLNPVPDEELRDLYGGTqhiplfqm--sdfygkgpSMKQFMDVFSLPEMCLILSVTDFFISn-NIEFDPVHLYKDI 226 tropical clawed...
XP_014344299 209 TAYRGLKPVPDEEVIEKYGGTqhiplyqm--sdfygkgpSLKQFMDIFSLPEMTLISCVNDYFINh-NIEFDPVHLYRDI 285 coelacanth
4OHF_D       161 QYCVDKVHSDGTLKNIIIKNLKKYVIREKEVVEGLKHFIRYGKKIFILTNSEYSYSKLLLDYALSpfldkgEHWQGLFEF 240 Legionella pneu...
EEB19928     239 RSAIGSIH--PVMHSEVMENTNKYLEENTDITKLLIKLKNAGKKLFLITNSPFHFVNKGLNVILG------QGWKDFFDI 310 human body louse
XP_002595182 186 KNAVISVHLSGDMHKAVAEDMDRYLERGEEIAQLLRRLAGAGKKLFLITNSPFWFVQRGMEYIAG------PSWMEMFDV 259 Florida lancelet
XP_005796446 272 KEAIRDVHVKGIMYRAVEADIGKYICYGEQSHAVLKKLSAHGKKMFLITNSPFDFVDRGMSYIVG------KDWRDLFDV 345 southern platyfish
XP_003269986 251 KDSIRDVHIKGIMYRAIEADIEKYICYAEQTRAVLAKLADHGKKMFLITNSPSSFVDKGMSYIVG------KDWRDLFDV 324 northern white-...
XP_014348827 274 KEAIRDVHVKGMMYRAIEADIGRYICYGEQTCAVLRKLAEHGKKMFLITNSPISFVDRGMNYIVD------KDWKDLFDV 347 coelacanth
XP_005801814 306 SEAIGMVHLKGYMYKWIMQDLDKFILRKEETDAVLHRLVSQGKKLFLITNSPFSFVDKGMTHMVG------KNWRDFFDV 379 southern platyfish
XP_008102124 261 TDAIRDVHIKGFMYKWIMQDLEKYILRGDETYAVLHRLAKSGKKLFLITNSPFSFVDKGMRYMVG------KDWRDFFDV 334 green anole
KAE8612924   227 TDSIKDVHVRGLVYTWIEKDMEHRILHGDEVYAVLNRLLNHKKKLFLITNSPFSFVDKGMKHMVG------GDWRDLFDV 300 tropical clawed...
XP_014344299 286 TDAIKDVHVKGMMYKWIEKDMENYILHGDETYAVLNRLVSNGKKLFLITNSPFSFVNKGMKHMVG------KDWQDLFDV 359 coelacanth
4OHF_D       241 VITLANKPRFFYD-NLRFLSVNPENG--TMTNVHgpiVPG--VYQGGNAKKFTEDLGVGGDEILYIGDHIYGDILRLKKD 315 Legionella pneu...
EEB19928     311 VIVQARKPKFFTDeTTPIRIFDTKLKtqLWDRVTk--LEKgvIYCEGTMKQLKEITGWVGSEVLYFGDHPYSDLADVTLK 388 human body louse
XP_002595182 260 VIAESRKPKFFTDtKRPFREVSKTSGtcKFERVTs--LRKgqVYIQGNLQDFRQMTGWYGARVLYFGDHVYSDLADPFLK 337 Florida lancelet
XP_005796446 346 VIVQADKPSFFNDrRKPFRRVT-DKGvlLWDRIHr--LEKgeIYKQGNLYEFLRLTGWRGSKVLYFGDHIYSDLADLTLK 422 southern platyfish
XP_003269986 325 VIVQAEKPNFFNDkRRPFRKMN-EKGvlLWDKIHk--LQKgqIYKQGNLYEFLKLTGWRGSRVLYFGDHIYSDLADLTLK 401 northern white-...
XP_014348827 348 IIVQADKPSFFNDrRKPFRRVN-QKGvlLWDKIHq--LEKgqIYKQGNLYEFLKLTGWRGSKVLYFGDHIYSDLADLTLK 424 coelacanth
XP_005801814 380 VIVQADKPHFFTDcIKPFRRLD-NNGdlRWEKINr--LDKgqIYKQGNLFDFLRLTGWRGSKVLYFGDHLYSDLADLMLR 456 southern platyfish
XP_008102124 335 VIVQADKPHFFNDcVKPFRRLD-NNGdlQWDKINr--LEKgqVYKQGNLFDFLRLTGWRGSKVLYFGDHLYSDLADLMLR 411 green anole
KAE8612924   301 IIVKADKPAFFTDwRKPFRRLD-EKGalQWDKINc--LEKgkIYKQGNLFEFLQLTGWRGSKVLYFGDHLYSDLADLMVR 377 tropical clawed...
XP_014344299 360 VIVQAHKPSFFTDkCKPFRRLD-ETGslQWDKINe--LEKgkIYKQGNLFDFLRITGWRGSRVLYFGDHLYSDLADLMLR 436 coelacanth
4OHF_D       316 CN--WRTA---------LVVEELGEEIASQIRALPIeKKIGEAMAIKKELEQkyvdlcTRsIdessQQyDQEIHDLQlqi 384 Legionella pneu...
EEB19928     389 HG--WRTG---------AIIHELTHEIQTLNKQSFK-MDSNWLQVLTQLIEE---------N----EY-LAEDESSEkev 442 human body louse
XP_002595182 338 HG--WRTG---------AIIPELEDEIKISNSTSYK-DTISWLLALQGLIES---------Q----QK-SRHDEAVQavv 391 Florida lancelet
XP_005796446 423 HG--WRTG---------AIIPELRKEIKIMNTPQYV-HMMTWLQALTVLIEQ---------M-----Q-AHRDPATQavv 475 southern platyfish
XP_003269986 402 HG--WRTG---------AIIPELRSELKIMNTEQYI-QTMTWLQTLTGLLEQ---------M-----Q-VHRDAESQlvl 454 northern white-...
XP_014348827 425 HG--WRTG---------AIIPELRSEIKTMNTEEYT-RVMAFLQTLTGLLEK---------M-----Q-VYRDTESQmll 477 coelacanth
XP_005801814 457 HG--WRTA---------AIVPELEHETKIVSAHRYA-VTLTWLQALTGLMER------LQ---------THRDPASKkvf 509 southern platyfish
XP_008102124 412 HG--WRTG---------AIVPELETETKMVNTEQYS-QALTWLQALTGLLER---------M-----Q-MFQDQESQqvl 464 green anole
KAE8612924   378 HGwrTGAIvpeleaeirIINSEQYMHSLTWQQALTG------------LLER---------M-----Q-MHQDAESKqvl 430 tropical clawed...
XP_014344299 437 HG--WRTG---------AIVPELEAEIRIINTEQYM-HSLTWLQAITGLLER---------M-----Q-MHQDAESKqvl 489 coelacanth
4OHF_D       385 stVDLQISRLLQEQNSFYNPKWERVFRAGAEESYFAYQVDRFACIYMEKLSDLLEHSPMTYFRANRRLLAHDI 457 Legionella pneumophila...
EEB19928     443 kqWIDERNYLLQSTKNVFNPQFGSVFRTYNNPTYFSRRLFRFADIYTSNLGNLLNYSLNHTFFPRRGALPHEY 515 human body louse
XP_002595182 392 qeWMKEMRELRHYTKDIFNPQFGSLFRTHHNPTYFSRRLMRFADIYTSSVANLLHFPIDYTFYPRRSALPHEI 464 Florida lancelet
XP_005796446 476 eeWIKEREAMKPQTKDIFNAQFGSLFRTYHNPTYFSRRLSRFADIYMASISCMLNYDLQHTFFPRRTPLQHEA 548 southern platyfish
XP_003269986 455 qeWKKERKEMREMTKSFFNAQFGSLFRTDQNPTYFLRRLSRFADIYMASLSCLLNYDVSHTFYPRRTPLQHEL 527 northern white-cheeked...
XP_014348827 478 qeWIKERQDTRELAKKVFNPQFGSIFRTNQNPTYFSRRLSRFADIYMASLSCLLNYDLHHTFYPRRTPLQHEA 550 coelacanth
XP_005801814 510 leWQKEREELRVMTKNLFNPQFGSIFRTCHNPTYFSRRLSRFSDIYMASLSCLLNYDPSYTFYPRRTPLQHEA 582 southern platyfish
XP_008102124 465 qdWMKERQELRALTKNLFNPQFGSIFRTCHNPTYFSRRLCRFSDIYMASLSCLLNYDLNYTFYPRRTPLQHEA 537 green anole
KAE8612924   431 leWLQERQELRALTKNLFNPQFGSIFRTFHNPTYFSRRLVRFSDIYMSSISCLLNYDINFTFYPRRTPLQHEA 503 tropical clawed frog
XP_014344299 490 seWWKERQELRSRTKNLFNPQFGSIFRTYHNPTYFSRRLCRFSDIYMSSISCLLNYDLNFTFYPRRTPLQHEA 562 coelacanth
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