1WDJ


Conserved Protein Domain Family
Uma2

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pfam05685: Uma2 
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Putative restriction endonuclease
This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.
Statistics
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PSSM-Id: 399004
Aligned: 140 rows
Threshold Bit Score: 58.9512
Threshold Setting Gi: 81710335
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1WDJ_B  14 EELRRLSElNPGYQWERsPEGRLWV-SPTGGESGRRSLQLAYQLARWNEErg-lgVVFDS-STGFKFp-DGSILSPDAAF 89  Thermus thermophilus
Q8YX17  13 DEYLELEi-ASEIRNEY-CDGEIIPmTGGTPNHNDIAGNLYILLKSAlks--knyRIFYV-DQRLWIpdANLYTYPDVMV 87  Nostoc sp. PCC 7120
O52306  12 EDYLEQEa-RSALRHEF-IQGKIIPmAGASANHNRLTLNLSRLL---PFEisdrqYEIFVsDMRLWLpdVASYLYPDVMM 86  Synechococcus sp. PCC...
P72821  16 EEYLQWEE-RQREKHEY-FDGQIYAmGGGSKNHSVISVRLSTLFCNHLDGgd--cEIGNS-DLKIQIvnTQNYTCPDVSV 90  Synechocystis sp. PCC...
Q8YZF4  14 EEYFAWEE-QQLEKHEY-INGEVYAmTGGSINHGRIGIRFTAMFDSHLENtg--cITGNS-DVKLNIfgSNNYTYPDASV 88  Nostoc sp. PCC 7120
Q8YWY2  14 EEYLAWEp-LQDLRYEY-VNGEVFAmTGGTIPHNDIALNFYRALYPHLRArg--cRVNVS-DVKVQVtpQSPYYYPDVIV 88  Nostoc sp. PCC 7120
Q7NKB7  13 QEYFEWEa-LQEYKHEY-VDGEVFEvTGGTIPHAAVTLNLAFSLKLHLRGgp--cRVFSS-DAKVGVseQGPFLYPDVVV 87  Gloeobacter violaceus
Q8YMM1  13 QEYLEWEe-RQDIKYEY-VNGEVFAmTGGTLPHTTIALNLASALKSHVRGgs--cRAFMS-DAKVAVseGMSFHYPDVVV 87  Nostoc sp. PCC 7120
Q7NM95  11 AEYIEWEt-HQQIRHEY-VNGEIFAmTGSSIAHNTIAVNVARLIGNYLEDsrspcRVFVS-DVKAQIteDGPFYYPDVMA 87  Gloeobacter violaceus
Q7NHF6  13 EQFLRWEr-EQPQKYEY-RYGRIFSmAGGSKSHNLIAVNVTAAVHGHLIDsl--cRVFNSdQKVACSp-AGPFYYPEVSV 87  Gloeobacter violaceus
1WDJ_B  90 VERGa-WEALSEAeregF-PPLAPKAVFEVRSASQDpEELRAKMGIYL-RNGVLLGVLVDPYARAVEVFRPG-----KPP 161 Thermus thermophilus
Q8YX17  88 LPKP--LELQTGC----KdTVLNPCFIAEVLSKSTQnYDRGEKFVAYRqIPIFQEYLLIDQYRIHVEHHIKTapnqwLFS 161 Nostoc sp. PCC 7120
O52306  87 IEGApvFLDESQM------AVTNPSMIAEVLSNSTEgFDKNQKFALYRtIPQLQEYLLIDQTYPRVELYQKVgdrqwLLT 160 Synechococcus sp. PCC...
P72821  91 TCDP---RDRKST----Q-FITYPCLVVEVLSPSTEaYDRGGKFRLYAhNPMLQDYLLVSSTSVEIDLYHKNddgdwLIL 162 Synechocystis sp. PCC...
Q8YZF4  89 TCDD---RDKTTT----R-YITYPCLIVEVLSKTTEaYDRGGKFRMYRqNPALIDYLLVSSTSIEIDLYHKNdagdwLII 160 Nostoc sp. PCC 7120
Q8YWY2  89 SCDP---QDINAR----R-FIQNPKIIAEVLSPGTSgKDRGEKFTNYLkIPSLQEYLLIDSETISVERYCRGegrmwLYY 160 Nostoc sp. PCC 7120
Q7NKB7  88 TCDE---RDRNAA----R-AIHFPTLVIEVLSPTTEaYDRGTKFRRYRrIETLSEYVLVDAERVGVDCFRRNpvgiwELH 159 Gloeobacter violaceus
Q8YMM1  88 SCDE---RDKQAT----K-FLQYPCLIVEVLSPSTEaYDRGAKFKQYRrIQTLKEYVLIDAEKINLDCFRLNengiwELY 159 Nostoc sp. PCC 7120
Q7NM95  88 TCDE---RDRNAV----Y-TIRHPCLIVEVLSPTTEaFDRGDKFGDYRrIDTLQEYMLFDSRKLAVEHYRREsertwKLV 159 Gloeobacter violaceus
Q7NHF6  88 SCDD---REEPTG----Y-MLQYPCLIVEVLSKNTAeFDRSVKFRDYGkIETLQEYLLLDSQVVAASLYRRQginlwQVQ 159 Gloeobacter violaceus
1WDJ_B 162 LRl-eGVERVSLdPELPGFALS 182 Thermus thermophilus
Q8YX17 162 EYd-dPTVTLSL-STF-ELQIQ 180 Nostoc sp. PCC 7120
O52306 161 EL---MGENAVIkFKFAALEIK 179 Synechococcus sp. PCC 7002
P72821 163 NYq--ASDRLEL-KSI-GLSFA 180 Synechocystis sp. PCC 6803 substr. Kazusa
Q8YZF4 161 NYk--PGDTIEL-KSI-NLSFP 178 Nostoc sp. PCC 7120
Q8YWY2 161 PYt--EGDTITL-SSI-EFELA 178 Nostoc sp. PCC 7120
Q7NKB7 160 PYteeDHEIRFAsLDLR---VS 178 Gloeobacter violaceus
Q8YMM1 160 SYe-eGNEVYLQsVDFR---FP 177 Nostoc sp. PCC 7120
Q7NM95 160 LYa--AEDTMHL-ESL-DCELA 177 Gloeobacter violaceus
Q7NHF6 160 LFe--EAEVLHL-DSI-AMELP 177 Gloeobacter violaceus
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