Conserved Protein Domain Family
CHGN

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pfam05679: CHGN 
Chondroitin N-acetylgalactosaminyltransferase
Statistics
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PSSM-Id: 399001
Aligned: 59 rows
Threshold Bit Score: 378.902
Threshold Setting Gi: 260783371
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ETN67624      217 HIPSCLKNLYSTHEDVEVGRCVQKFAG-IP-CTWNYEMQSILHHN-SSGYRAFS----GTL-----KSKEVHNAITLHPI 284  Anopheles dar...
PDM68310      221 QRHVCNN-MLAGSDEQGMEMCIHAATN-VS-CRTEHQGREYRFWRvSGTESPHEeiqrWSM-----ETPSLNSSLSVGSI 292  Pristionchus ...
XP_001601123  232 NLDWCVKTTFSSSDDVNIGRCILHSAS-LP-CTHKAQEQIYFSTKlNVtf------dyQNDfkklcADEDFQKSITIYPI 303  jewel wasp
EGI68285      394 NLDWCVKNAYSDSDDVNFGRCILHSTS-MP-CTNHIEGRNLTFIQlKSif------nfEKDfvqltEQNEFQNSVSIYPV 465  Panamanian le...
XP_001946198  231 NVDWCVRNAFSTSDDDNFGRCVLHSVN-LP-CQTSIQGQTISSYRlWEAKDLINllnqPQ------QQDSFNRALTVYPM 302  pea aphid
Q29IB5        171 NLDRCVRIGITGDHSVNIGRCVKYASH-VPgCQESFQGMRQYSYAlN--TPGRQrrdfSELa----KEEAFRNASTVYPV 243  Drosophila ps...
XP_001868610  241 NLDWCVRNSVSNQHNLNIGRCVKYSSKiDS-CQTSWQGINVTSYKlNsy-------kiYRDlhmikHEAAFNRASVIYPI 312  southern hous...
Q16SL4        240 NLDWCVRNAASNQHNLNIGRCVKYSSKiDG-CQPSWQDINVTSYKlNsy-------kiYRDlhlikREDAFNKASVVYPI 311  yellow fever ...
ETN62052      261 NLDWCVRNALGDDHSHNIGKCVKYSAKlDG-CHDRWQGIAVSSYRlSsf-------kiYRDfhliaKEPAFNGASTVFPV 332  Anopheles dar...
XP_318249     241 NLDWCVRNAVSNYHSVNIGKCVKYSAKiKT-CHQSWQGVDITSYNiAgy-------kiYRDfhliaEQEAFNKAAMVYPI 312  Anopheles gam...
ETN67624      285 KQPAFMYRLHAYMLGLSAQELRQHSLLLHRDIAMATS-LLQL---PQinknlapgvpifpqdennidylgdHNVLGATPD 360  Anopheles dar...
PDM68310      293 LSTADASALHDHFIRVEVDKVEAEILKMEEEIEGMEE-DLPDg---------------------------pSWPIGTKPF 344  Pristionchus ...
XP_001601123  304 YDHLMIYNINTHFAEMELLKVEKEIDSLRKQIVKTTS-FTPKnqqDL------------------------SWPIGNQPG 358  jewel wasp
EGI68285      466 YDYKLIYKFNMYFAAINSIKVHKQINDIRKIISATAH-LGPPnqrNI------------------------SWPIGNQPG 520  Panamanian le...
XP_001946198  303 PNAETMYKTHLAFCKMNLEKSNMEIDALRRSIVAESS-LEPPsfrKV------------------------SWPVGSQSG 357  pea aphid
Q29IB5        244 PTPEDFYRLHAYYSKQHLETVQERGYALEQKSYRIANgSISNkilEI------------------------RWPLGVPPP 299  Drosophila ps...
XP_001868610  313 TTADDFYLLHAYFSRVHLEQINAAKEQIHLEASAISN-G-TLsndILe----------------------vRWPLGVPKP 368  southern hous...
Q16SL4        312 TTADDFYLLHAYFSRVHLERINQQKQQIHDQASTISN-G-TLpndVLe----------------------vRWPLGVPKP 367  yellow fever ...
ETN62052      333 TVADDFYLLHAYFSRVHLETNNERKRQLQEEALQIAG-G-ALpndVLe----------------------vRWPLGVPRT 388  Anopheles dar...
XP_318249     313 TSMDDFYLLHAYYSRVHLKQNTIVKRLLQNDAMQLSN--RTLsndILe----------------------vRWPLGVPKS 368  Anopheles gam...
ETN67624      361 LNrhrPRTLDELIQWDFIA-KSLYSSQHPN--PKRRMESSIKEGLSDVIREIMEHINNFSRQRgrMIEFRELLYGYMRVN 437  Anopheles dar...
PDM68310      345 AH---APNRYQVPVWEFFTaTEIFKNEPNQ--NVRPITGSDKEDIDEIIESAKRKAEEEEGDR--RVEFVRVSGGYRQFD 417  Pristionchus ...
XP_001601123  359 SN---AMNRFDILRWTYFNmTHVFLDDDFG--TVKELNDYQKEDVNNVVNVTVKRVVDNYNKQ---LKFNKLLNGYWKFD 430  jewel wasp
EGI68285      521 NR---PLGRFDVLRWSYFNmSHVFFETDFI--NIQELKGDTKADIDNVINTAVNNIISKYDNK---LSFVRLLNGYLKFD 592  Panamanian le...
XP_001946198  358 ST---PSTRFDVLKWEHFTeTHLYLDSRIS--NIRPLNEAENADIHNVLNTSIEYLESKYSNN---MKFDRLVNGYKRFD 429  pea aphid
Q29IB5        300 SA---PETRHDILIWQMLNeTHSYLPNGNVehAVAPLTRIEALDFAKVLEIALQYAALKHPGL----SYHSLHTAYRKFD 372  Drosophila ps...
XP_001868610  369 NP---SESRHDIIPWTHLNlTHSFMYTSEI--NVRPLSSVDAEDMQNILNKTILEAHRTNPQL----EYRGLHSAYRKFD 439  southern hous...
Q16SL4        368 NP---PESRHDIVPWTHLNlTHSFMWNSEL--NVRPLSTVDAEDMQNILNKTILEAFRTNPHL----EYRSIHSAYRKFD 438  yellow fever ...
ETN62052      389 SP---PESRHDIIKWTTLNlTHIFMRNTEE--NVRRLSAVDEQDIRNVLNKTVTEATRNQPDA----EYRGLHSAYKRFD 459  Anopheles dar...
XP_318249     369 NP---TESRHDVVPWVTLNtTHSFMWQSEV--NVKRLSAIDEEDIRNVLNKTILHAIRTHPDA----EFRGIHTAYKRFD 439  Anopheles gam...
ETN67624      438 SMYGQDLILDLLLVYK-KYRgkkmTVPVRRHLYIQRSFTEIRVReitaqimpsqasvnqaehvssvgitkqprdpatsfd 516  Anopheles dar...
PDM68310      418 AARGMDYMVDLVYRDVnNEE------TIERRIHLARIIERTTLV------------------------------------ 455  Pristionchus ...
XP_001601123  431 SSRGVDYILDLSFATDsGV-------EVNKRIEVCKPLGKVEILpvpy-------------------------------- 471  jewel wasp
EGI68285      593 ASRGMDYILDLVFNEVaTSK------EIRKRIEICKPLGKVEIIpvpy-------------------------------- 634  Panamanian le...
XP_001946198  430 PSRGLDYILDLTFKDIvGNR------LIQKRVEVSKLLGKVEMLsvpy-------------------------------- 471  pea aphid
Q29IB5        373 ATRGMDYQLHLNLQKGsGRR----RRLLLKSFEVVKPLGRVEVVpspy-------------------------------- 416  Drosophila ps...
XP_001868610  440 AVRGMDYRMHLSFYDRgRRE------HVLKSFEVVKPIGLIEIVpspy-------------------------------- 481  southern hous...
Q16SL4        439 AVRGMDYRMHLNFYDRkRRQ------PVLKSFEVVKPIGLIEIVpspy-------------------------------- 480  yellow fever ...
ETN62052      460 AVRGMEYRLLLNFYDRkRKR------MRTRSFEVIKPISLIEIVpspy-------------------------------- 501  Anopheles dar...
XP_318249     440 TVRGMDYRLLLNFYDRkRRT------MVQKSFEVIKPISLIEIIpspy-------------------------------- 481  Anopheles gam...
ETN67624      517 rishrvktlfnelerltdsigsnlkekeN-------KDRVVFILPLSGR--SETFKRFLRNFEEVALRQeDQRT-DLLVA 586  Anopheles dar...
PDM68310      456 ----------------------------NtvpyvkeDADLTIVVPIAEEveVLPGRRLLARQARLCTSPtEENR-HTRVV 506  Pristionchus ...
XP_001601123  472 ---------------------------------vteNSRINMIIAVDAFk-KEECMKFLAHYADTCMDR-KDKVtLTVVL 516  jewel wasp
EGI68285      635 ---------------------------------vteNTRINIIITIDLSk-KQDAVNFIEHYSQNCMEK-KCKTyLMVVL 679  Panamanian le...
XP_001946198  472 ---------------------------------vteNTRVHILLPVRTNe-REDAFRFLRQYKQVCIDK-KEKTmLMLVL 516  pea aphid
Q29IB5        417 ---------------------------------vteSTRIAILVPAFEHq-VPDALEFVAQYERLCMQN-QDNTfLLLIF 461  Drosophila ps...
XP_001868610  482 ---------------------------------vteSTRIAILLPTLEHq-VHDAEQFVQHYEKTCMDN-QDNTfLMLIF 526  southern hous...
Q16SL4        481 ---------------------------------vteSTRIAILLPTFEHq-VPEALQFVQSYERVCMDN-QDNTfLMLIF 525  yellow fever ...
ETN62052      502 ---------------------------------vteSTRVAILLPVLEHq-VQETEQFLESYERTCMDS-QDNTfLMLIF 546  Anopheles dar...
XP_318249     482 ---------------------------------vteSTRVALLLPVFESq-ILEAEQFMELYEKTCMES-QDNTfLMLIF 526  Anopheles gam...
ETN67624      587 LYVE--------APESSELITQLLNLRARYPGSR--INYLPLT-----------------------GNFSRGVALDRAIR 633  Anopheles dar...
PDM68310      507 VAVSar----veHKSLIFIQNDLEELKKRCKRSS--LEASLLSvss-----------------dnpSSLHAAEALDEAID 563  Pristionchus ...
XP_001601123  517 LYNPgyas-kgnEDIFHEIKKRALFLTEKYKKDQlkVTWLSIRlptis-------------sfieiEPLLKIAIADLYVK 582  jewel wasp
EGI68285      680 LYNSdsps-kgkGDVYLDVKTYISMLNEKYKKDQskITWLSIRlpvnv-------------tsvdlDPMLKIAVTDLCAK 745  Panamanian le...
XP_001946198  517 LYDAnapgkgavDDVFKQLKDEATSLSNAHKKDGtkVAWLSVKipntk-------------llalrDALLDFAIIDLAIR 583  pea aphid
Q29IB5        462 LYRLdsps-kgdEDPFKGLKTLALDLSSKYKTDGsrIAWVSIRlpeqlseavrpedwllhasmygpKQLLSLVVADLALP 540  Drosophila ps...
XP_001868610  527 YYRAetps-kgdEDVFLPLKNLALSLTDRHKQDGsrIA---------------------------------FAAADLALR 572  southern hous...
Q16SL4        526 YYRAdtps-kgdEDVFLPLKNLALGLTDKHKQDGsrIAWVSIRlppelsapfnl-nhlystslygpNQLLSFVATDLALR 603  yellow fever ...
ETN62052      547 FYRAdtps-kgdEDVFLPLKNIALAVTEKHKQDGsrVAWVSIRlppelsgkfdd-nhryyssmygqHGRLAFAAVDLALR 624  Anopheles dar...
XP_318249     527 FYRAetps-kgdQDVFLPLKNIALALTEKHKQDGsrVAWVSIRlpidesitfnn-snryssslnvpQTLMNFVAVDLALR 604  Anopheles gam...
ETN67624      634 SSycASDDIIFFIDVDMIFTVQSIDRIRLNVIRGRQIYLPIVFSEYDPQMMG----WQAetqivmqgsmggytslknfal 709  Anopheles dar...
PDM68310      564 HF--GPQSMFLLLSPYADIQKELLDRARINTIKKFQVFLPIPFIEYHPTISGmdlkDGEkpddestrqral-----gtlk 636  Pristionchus ...
XP_001601123  583 KF--SSDNLILFADTRMELKSEYLNRVRMNTISQWQVFSPIPFVQYNPDIIYydasVKH--------------------- 639  jewel wasp
EGI68285      746 KF--SSESLILLVETGTKLKIDYLNRVRMNTINRYQIFSPIPFIEYHPDIIYadevVTH--------------------- 802  Panamanian le...
XP_001946198  584 KF--PPDALMMLARPKMEIRQDYLNRVRMNTIMEWQIFSALPFSEYDPNLMTyprqA----------------------- 638  pea aphid
Q29IB5        541 KL--GLESLVLLATPGMSFKADFLNRVRMNTIQGFQVYAPIGFQMYPCRWAQfckeCE---------------------- 596  Drosophila ps...
XP_001868610  573 KI--GLDSLVMICSAEATFRSDFLNRVRMNTIAGFQVFSPIAFRQYPCGWTKlckeCD---------------------- 628  southern hous...
Q16SL4        604 KI--GLDSLVMICSSSATFRSDFLNRVRMNTIAGFQVFSPIGFTMYPCRWTKlckeCD---------------------- 659  yellow fever ...
ETN62052      625 KI--GLESLVMLCSNAATFRSDFLNRVRMNTIQGFQVFSPIGFNMYPCEWTGlckpCE---------------------- 680  Anopheles dar...
XP_318249     605 KI--GLESLVIVCTNSASFRPDFLNRVRMNTIQGFQIFSPIGFMMYPCEWTGlcklCE---------------------- 660  Anopheles gam...
ETN67624      710 pllpenfSLPYRITDENGYFRQFGYGLAGMYKADLQRpdlkgFSTDITGWGLED---V---------------------- 764  Anopheles dar...
PDM68310      637 daappqrTKGLMVQKEHGRFDPLDFSVVCIYGSDYME-----VRPRLM--NGKR---I---------------------- 684  Pristionchus ...
XP_001601123  640 --------VDFDIIHNHGRYDDYNYDSVSFYTKDYMT-----VRKSIE----NQ---Vplvrtdkdias-------mlql 692  jewel wasp
EGI68285      803 --------DEVDVNSNYGKYDEQNYNNIAFYIKDYNA-----MRQTVE----AN---Iplvrsdkdiat-------llkl 855  Panamanian le...
XP_001946198  639 ---------TLDVNKYYGHFDPFDYDHLSFYAKDYVV-----ARKRAE----SL---Ipiirvdrdihhlvtestshslk 697  pea aphid
Q29IB5        597 ---------ACDVAQSSGYFDRHNHDVIAFYSRDYVQ-----ARKLLHPQGLPI---Irsdldidqlle-------pasq 652  Drosophila ps...
XP_001868610  629 ---------GCDVGQSTGYFDRANYDVVAFYSRDYVD-----ARKLLE----QQsgrLpivrsdrdivnlln-ytqdaig 689  southern hous...
Q16SL4        660 ---------GCDVGQSSGYFDRANYDVVSFYSRDYVE-----SRKLLE----QQ---Lpivrsdrdivn-------lvny 711  yellow fever ...
ETN62052      681 ---------NCDVGQGIGYFDRHNYDVVSFYSNDYVA-----VRKELE----SR---Lpivrsdrdivnllgtnatgpvp 739  Anopheles dar...
XP_318249     661 ---------NCDVGQSSGYFDHDNYDVVSFYSNDYVL-----ARKKLE----AL---Lpivrndkdilnfi---stissh 716  Anopheles gam...
ETN67624      765 -------VFIENVIAlnhrgnqrlvaiadgrwdplrmrtsgaslnpkpssstvtgpsstahiptippavngvEELIIFRA 837  Anopheles dar...
PDM68310      685 -------DVGSAFLNm-------------------------------------------------------pPGVHILRA 702  Pristionchus ...
XP_001601123  693 sqtisigSIFEMFVVf--------------------------------------------------------SNLNTFRA 716  jewel wasp
EGI68285      856 skhspvtSLFEMYVSf--------------------------------------------------------SDMHVFRA 879  Panamanian le...
XP_001946198  698 vvnmtnpSVYSMFVAy--------------------------------------------------------SECHIFRA 721  pea aphid
Q29IB5        653 srpegveSILDMFVAa-------------------------------------------------------qHSVHILRG 677  Drosophila ps...
XP_001868610  690 splerieNVAEMFVRa-------------------------------------------------------sGKIHVLRG 714  southern hous...
Q16SL4        712 tqedgiqNVAELFVRa-------------------------------------------------------nTKIHVLRG 736  yellow fever ...
ETN62052      740 ptggpltNIVQLFLQa-------------------------------------------------------nTDLHVLRA 764  Anopheles dar...
XP_318249     717 ysnptisNIADLFTQs-------------------------------------------------------nNKMHVLRA 741  Anopheles gam...
ETN67624      838 PDPSLV----------------HIFHPIQCD-------TNLEEAQYKMCLGTKANTLGSLRTL 877  Anopheles darlingi
PDM68310      703 IEPALR----------------LRYHRRECD-------PDLEEDDLLRCTQSRRENLAAKDQL 742  Pristionchus pacificus
XP_001601123  717 VEPALK----------------LKYKEINCI-------GTRNNITLNTCLKQRNLQLGNRGQL 756  jewel wasp
EGI68285      880 IEPTLK----------------IKYKDVNCD-------DVSNDNIYKNCLKLRNNHLGKRSQL 919  Panamanian leafcutter ant
XP_001946198  722 VESGLR----------------LRHKQRHCElyegnivDHTSAALYGNCVRSRNRNAGSKGQL 768  pea aphid
Q29IB5        678 VEPNLR----------------FGHDVRNHLgr----gSTLPEQLPEQCGREQCIHLASRKQI 720  Drosophila pseudoobscura
XP_001868610  715 IEPNLRlgramenflaevdpegEQLQRLRCEe------QPDQ---RDRCVR-----IASKKQI 763  southern house mosquito
Q16SL4        737 IEPNLRlgramenf-lasdpegEQLTALRC-----------EESNEERCVR-----IASKKQI 782  yellow fever mosquito
ETN62052      765 IEPNLRlgssirnf-latdpngERFARLSCPe------PDDN---RQQCIR-----IASKKQI 812  Anopheles darlingi
XP_318249     742 IEPNLRfgrsvins-lskdhsgKQISEFRCS----------KQKEKNKCIK-----VASKKQI 788  Anopheles gambiae str. PEST
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