3WIN,2E4M


Conserved Protein Domain Family
Botulinum_HA-17
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pfam05588: Botulinum_HA-17 
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Clostridium botulinum HA-17 domain
This family consists of several Clostridium botulinum hemagglutinin (HA) subcomponents. Clostridium botulinum type D strain 4947 produces two different sizes of progenitor toxins (M and L) as intact forms without proteolytic processing. The M toxin is composed of neurotoxin (NT) and nontoxic-nonhemagglutinin (NTNHA), whereas the L toxin is composed of the M toxin and hemagglutinin (HA) subcomponents (HA-70, HA-17, and HA-33).
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Statistics
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PSSM-Id: 283282
Aligned: 5 rows
Threshold Bit Score: 204.426
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3WIN_C        24 SAERTFLPNGNYNIKSIFSGSLYLSPVSGSLTFSNESSANNQKWNVEYMAENRCFKISNVAEPNKYLSYDNFGFISL--- 100
O06016         2 TAERTFLPHGNYKIKSIFSDSLYLTPLSEIITFLNTSSENNQKWKLQYVEEKNAYKISNIAQPDKYLTYNSSQFIVLkni 81  Clostridium bot...
WP_012291566   2 SAERTFLPNGNYNIKSIFSGSLYLSPVSGSLTFSNESSANNQKWNVEYMAENRCFKISNVAEPNKYLSYDNFGFISL--- 78  Clostridium
Q9LBT0         2 SSERTFLPNGNYKIKSLFSNSLYLTYSSGALSFSNTSSLDNQKWKLEYISSSNGFRFSNVAESNKYLAYNDYGFIYL--- 78  Clostridium bot...
2E4M_C         2 SSERTFLPNGNYKIKSLFSDSLYLTYSSGSLSFLNTSSLDNQKWKLEYISSSNGFRFSNVAEPNKYLAYNDYGFIYL--- 78 

3WIN_C       101 -DSLSNRCYWFPIKIAVNTYIMLSLNKVnelDYAWDIYDTNENILSQPLLLLPNFDIYNSNQMFKLEKI 168
O06016        82 gDSTALENYWIPYKIASNTYIITNLKEY---DKAWDIYDLNGDISDQPLLLQQLFYYEKSNQMFIFEKI 147 Clostridium botulinum
WP_012291566  79 -DSLSNRCYWFPIKIAVNTYIMLSLNKVnelDYAWDIYDTNENILSQPLLLLPNFDIYNSNQMFKLEKI 146 Clostridium
Q9LBT0        79 -SSSSNNSLWNPIKIAINSYIICTLSIVnvtDYAWTIYDNNNNITDQPILNLPNFDINNSNQILKLEKL 146 Clostridium botulinum
2E4M_C        79 -SSSSNNSLWNPIKIAINSYIICTLSIVnvtDYAWTIYDNNNNITDQPILNLPNFDINNSNQILKLEKL 146
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