6HSY,4FCZ,5UWA,2QGU


Conserved Protein Domain Family
MlaC

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pfam05494: MlaC 
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MlaC protein
MlaC is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. This family of proteins is involved in toluene tolerance, which is mediated by increased cell membrane rigidity resulting from changes in fatty acid and phospholipid compositions, exclusion of toluene from the cell membrane, and removal of intracellular toluene by degradation. Many proteins are involved in these processes.
Statistics
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PSSM-Id: 398898
Aligned: 278 rows
Threshold Bit Score: 58.7706
Threshold Setting Gi: 406653748
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6HSY_A         10 QGTVDELLSDIKANKAAYkadpQKLYATLDRILgpvvDAEGIAKSVMTVkySRQASPEQIKRFEEVFKNSLMQFYGNALL 89  Pseudomonas ae...
Q2W299         34 KQAVADATAAFAGGPFSR----EVSRDKVSALVskygDIAYESELILGRy-WRKATEPQKDSFVSLLIPFFVATYAELID 108 Magnetospirill...
WP_007423548   40 IKQSGDHLVAIVNGPDST----KVKADKLRELVdrivAVDQIGRFVLGRy-WRVATPAQQQEYLRLFHQTLAYNITNQIR 114 Acidiphilium
EFG85593       39 vhdFGNKLVAIVNNDISL----PQKKQQIEPLLeqnvDVDAIGRYCIGRy-WRIATPEQQTHYLQLFHQVLVNAITDKIG 113 Komagataeibact...
WP_003624853   37 iQVFGNQLVAIVNSPIPL----AEKKEKVLPLVqknvDIDGIGRYCLGRy-WKTASPDQQQRYLGLFHQVLVNAITDKLG 111 Acetobacter pa...
jgi:Caul_1575  52 QTKAQRVIAVLADRNQSV----SQKKATFHQAIddlaDVPKVTNFVLGKy-ARTITPDQRARFAAAFRIYAEGVYQNRID 126 Caulobacter sp...
Q9A273         52 QTKAQRVISVLASKSMSE----AQKKQVFHQAVdelaDVPRITNFVLGKy-ARTITPEQRARFTPVFRTYAENVYQSRIS 126 Caulobacter vi...
WP_015826221   32 EENANAVLHTLNQPELTE----ADRTAQFNLYMntfaDMDKVARFAVGRy-GRQFSDAEFKAYSDAFITYALAVYEVQLD 106 Hirschia baltica
Q0C0E0         32 QKNANEVLSTLNNPELSS----KERTEKFSEYMnefaDFDAISNFVIGKy-SRRFSKDELTAYRTAFRNYAMAVYENELD 106 Hyphomonas nep...
Q2RU67         39 QELSRYAIEDILKADVEP----SERIKRFETLLdtafDMPFIARFVVGGy-WKQATEDERAKFLSLFRDLNVINWGSRFG 113 Rhodospirillum...
6HSY_A         90 EYDNQ-DIRVLPSS-AKPSDDrasVN--MEIRDSKg-TV-YPVSYTM-T---NlAGGWKVRNVII----NGINIGKLFRD 155 Pseudomonas ae...
Q2W299        109 NKSGStQVLFLGSEeMADgv---vVK--ARIMQPA--EEgVDLSFVIsRs--P-AGKLVISDAIA----EGVGLVTTIRS 174 Magnetospirill...
WP_007423548  115 AYKGV-QFAVDGTKpGP--EGe-mVS--TTVTRPGq-SP-ADVQWVVdT---V-GGKPRIVDVVV----EGTSLRITERS 178 Acidiphilium
EFG85593      114 DYRGV-SFTVGPATpSG--Edi-aVS--TVINRPGq-PA-ANTEWVIsS---S-SGAPKVVDVVG----EGASLRLTQRQ 177 Komagataeibact...
WP_003624853  112 EYRGV-NFTLGNVTsTG--AGeyaVD--STLVRPQq-PA-AAMQWIVsE---A-SGSPKVVDVIG----EGASLRLTQRN 176 Acetobacter pa...
jgi:Caul_1575 127 DYHGE-ALKVTGSTvRK--PGdviVN--SVISGGQvgQP-LPVSWRVmG---G-GASWKVVDVQF----KGVWLAITQQQ 192 Caulobacter sp...
Q9A273        127 DYRGE-QLKVTGSVvRK--PGdviVN--TVVAGGQlsQP-VPVSWRVlN---S-GGAWKVVDVQF----KGIWLAITQQQ 192 Caulobacter vi...
WP_015826221  107 RFRGE-EIEVVGSVdLR--PGdsvVK--TRILATNdnKK-FNVEWRV-LkdkD-SANYQVLDVALniegSQIWLAQEQRA 178 Hirschia baltica
Q0C0E0        107 AYRGE-AVTVKNSVdRSATds--iVN--TVIKRNDg-RD-MDVRWRVlG---K-DGSYQVVDVALnldgNLIWLAIEQRA 175 Hyphomonas nep...
Q2RU67        114 DYGGQ-KIVVVNSVsRDSRGGt--IHevTTAIGKAndKP-MQVIWVLrAa--P-SGQLGVIDLKV----EGVSMALTFQS 182 Rhodospirillum...
6HSY_A        156 QFADTMQKNrndLEKTIAGW 175 Pseudomonas aeruginosa PAO1
Q2W299        175 DFTSVVRGAggnLDVLLDAM 194 Magnetospirillum magneticum AMB-1
WP_007423548  179 DYSSVINDNggqVSALLDAM 198 Acidiphilium
EFG85593      178 DYSSYIARNggnVDALLHAL 197 Komagataeibacter hansenii ATCC 23769
WP_003624853  177 DYSSYIARNggnVGALLDAL 196 Acetobacter pasteurianus
jgi:Caul_1575 193 DFVSTIDNAggnINVLIAQL 212 Caulobacter sp. K31
Q9A273        193 DFVSTIDNAggnIDVLINQL 212 Caulobacter vibrioides
WP_015826221  179 QFVSLLDRSngnAEVLIERI 198 Hirschia baltica
Q0C0E0        176 QFIALLDQNngsADVLINKI 195 Hyphomonas neptunium ATCC 15444
Q2RU67        183 EYRSVLKNSg-sMTGLNAVL 201 Rhodospirillum rubrum ATCC 11170
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