Conserved Protein Domain Family
UMP1

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pfam05348: UMP1 
Proteasome maturation factor UMP1
UMP1 is a short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex. UMP1 is required for the correct assembly and enzymatic activation of the proteasome. UMP1 seems to be degraded by the proteasome upon its formation
Statistics
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PSSM-Id: 398817
Aligned: 69 rows
Threshold Bit Score: 115.388
Threshold Setting Gi: 588259391
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q7S8I1        41 P--LDSVKSssSS---SSGATAtasavPISSHPLESRLKQWEATRETLRMETLRRTFGMAEPIRRQMELKIVRDG-EWKP 114 Neurospora crassa
XP_001846424  18 FagHVEPRD-------ENCAAQ-----LRFGHPLKQSELNYDQHRQNLNLQMLRNREGLAAPLKLTMELKSVSKV-GHLP 84  southern house ...
Q9VIJ5        14 SvlNATGRV--GMpteANCLNQ-----LAHVHRLRDSELNYNEHQYNRNMQMLRNHEGLGVPLKMGMERFAARQV-GRLP 85  fruit fly
XP_001989246  14 HvlNASGRA--ALpteQNCLSQ-----LAHVHRLRDSELNYNDHRYNIDMQMLRNREGLGAPLKMGMDRFAARQI-GRLP 85  Drosophila grim...
2_pfamImport   4 YgvTSSLRT--GL---GNVRSS-----LKHSHQLEISEKNYESNLRETEYNMLRNSQGIHAPLRKRMELTAVQKAtTRLP 73 
XP_006012796  26 YgvQDTLRK--GF---SSVKNE-----LLPCHPLELSEKNFQLTHDKMNFTTLRNIQGLHAPLKLQMEYKAVKQI-QRLP 94  coelacanth
XP_003459532  50 YgvQDSLRS--GF---TSVKNE-----LLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLHAPLKLQMEYRAARQI-QRLP 118 Nile tilapia
Q9CQT5        25 FesHDLLRK--GF---SCVKNE-----LLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQV-HRLP 93  house mouse
XP_417119     25 FegHGLLRR--GF---ACVKNE-----LVPSHPLELSEKNFQLNQDKTNFAMLRNIQGLHAPLKLQMELRAVKQA-QRLP 93  chicken
XP_002906885  10 RapPDALRF--GF---YSASED-----VRPVHEVQRLQTTHRQSNWELKMATVEQVYGKAAAMRLRSEKAVLEQF-TRLP 78  Phytophthora in...
Q7S8I1       115 LaLGggvgmmggmgNVHEEILMGRDGDITWEDVYTg-eESRAEV-SVHEEMERKL 167 Neurospora crassa
XP_001846424  85 F-LPs--------tNVARDVLTGRDELIDYTDIFNlaeNSEIMA-QPHAVMEKNL 129 southern house mosquito
Q9VIJ5        86 F-LSs--------sNFMDDVLTGRCDSIGFEDFMNlpeNSEHMR-QPHAVVEKSL 130 fruit fly
XP_001989246  86 F-LQs--------sNIMDDVLTGRCDEISFEDFLNlpeYNENLR-QPHAVVEKSM 130 Drosophila grimshawi
2_pfamImport  74 S-LPs--------sNFAMDILNGNDTCISIEDNFcr-gDTEVMG-DPHLMMEHKL 117
XP_006012796  95 F-LPs--------sNIALDILRGNDECIGFEDILNdptECEVMG-EPHIMVEYKL 139 coelacanth
XP_003459532 119 F-LQs--------sNLALDTLRNSDESIGFEDVLNdpaQSEVMG-EPHMMVEYKL 163 Nile tilapia
Q9CQT5        94 F-LPs--------sNLSLDILRGNDETIGFEDILNdpsQSELMG-EPHVMVEHKL 138 house mouse
XP_417119     94 F-LHs--------sNMALDTLRGNDECIGFEDILNdpsQSEVMG-EPHMMMEYKL 138 chicken
XP_002906885  79 G-LPs--------sHAGLDTLTGADEQIEFTDFLNdpnEHPENTfRVHEAMEVKL 124 Phytophthora infestans T30-4
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