6HHN


Conserved Protein Domain Family
rhaM

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pfam05336: rhaM 
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L-rhamnose mutarotase
This family contains L-rhamnose mutarotase which is a glycosyl hydrolase that converts the monosaccharide L-rhamnopyranose from the alpha to the beta stereoisomer. In Escherichia coli this enzyme is the product of the rhaM gene (also known as yiiL). The tertiary structure has been solved, in complex with L-rhamnose, and the catalytic mechanism determined. His22 is the proton donor. The enzyme naturally exists as a dimer.
Statistics
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PSSM-Id: 428428
Aligned: 245 rows
Threshold Bit Score: 64.0598
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6HHN_A            14 RLAFKMKLN--KGQKQAYKERH--DQLWPELKQLLKDNGVSEYSIFidEETNTLFAFQKVsGHG-----GSQDLAN-NEI 83  Formosa aga...
WP_008505873      12 RYCKTMELRndPALIEAYKLAHakGAAWPEITQGMRDVGIIDMEIY--LLGTRLFMIMDT-VTEfd-hdKAMAELAlKPR 87  Mucilaginib...
jgi:MICPUN_58616   4 cYAQTICLKndPRGIEEYKRHH--ADCWPEVLGALKAVGVLRMKIF--LLETRMFMYMET-EDDfdpevDFPRHLEmSPR 78 
Q017X5            20 TYAQTIELR--ADGVEEYVRLH--AAVWPEVLSSLRSVGVLQMKIW--TSGRRAFMYMET-TDAfdpdvDFPRHMAmSEK 92  Ostreococcu...
jgi:OSTLU_40891    7 TFAQTIELEs-EDAIEAYDALH--ARAWPEILESLRAVGVVDMFIY--RSGVRLFMHMTT-VDAfdpdvDFARHMAmSER 80 
XP_003063654       4 HYAQTICLRdgAGVVDEYKAYH--AEAWPEVCDALSAVGVEEMRIW--LVGRRLFMAMST-SDAfdpevDFPRHMAmSPR 78 
XP_004363146       4 SYASALDLKddKVLIEEYKKYH--QNVWPEVKNSLLGIGILEMKIY--LLGNHLFMYYET-NDSfdpqvDFQRYATdNPK 78 
Q556R9             8 SYAQALDLVndKELIEEYKKYH--KNVWKEVNEALCSIGIKKMKIF--LLGTHLFMYYEA-RADfdpkiDFQKYTElTPK 82  Dictyosteli...
EFA85985           4 sFAQALDLKndAELIEEYKKYH--KSVWVEVKNALKSIGITKMKIF--LVGNHLFMYYEA-EDDfsperDFQRYTDlTPR 78 
XP_003293016       8 cFAQALDLKndKELIDEYKTFH--KSVWPEVTDALKKIGITKMKIF--LVGNHLFMYYET-VPDft-peNYQSY-AvEPK 80 
6HHN_A            84 VKKWWDFMADIMQVNPDnspVSIP-----LEEVFY 113 Formosa agariphila
WP_008505873      88 QSEWEAHMSRFQDSNAEataDqkw---qlMERIYK 119 Mucilaginibacter paludis
jgi:MICPUN_58616  79 CVEWGKLMSTFQTPAPEakdGeww---ayMEEVYD 110
Q017X5            93 CVEWGALTRTFQSPVEEakeGeww---crMEECFD 124 Ostreococcus tauri
jgi:OSTLU_40891   81 CVEWGEVTRALQRPAPEakvGeww---trCRRVFD 112
XP_003063654      79 CVEWGARMRAFQTPPPEameGdww---tyMECVFD 110
XP_004363146      79 TSEWDNLMRKFQQKLKEakpTeww---asMEQVFD 110
Q556R9            83 ANEWDNLMRKFQQKISDipeNQLGewwspMDLVYD 117 Dictyostelium discoideum
EFA85985          79 ANEWDLLMRKFQQKISEakeSdww---apMEEVFD 110
XP_003293016      81 AQEWDSLMRKFQQKISEakeTdww---tdMELVFD 112
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