Conserved Protein Domain Family
AAR2

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pfam05282: AAR2 
AAR2 protein
This family consists of several eukaryotic AAR2-like proteins. The yeast protein AAR2 is involved in splicing pre-mRNA of the a1 cistron and other genes that are important for cell growth.
Statistics
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PSSM-Id: 398787
Aligned: 100 rows
Threshold Bit Score: 189.024
Threshold Setting Gi: 629672846
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002948987  22 QG-GALLVLGLPEGSYFGIDHMAFR-CGPR-FRGVKMLPPGPHFVCYSVPGSeq--------rGGGMSPVTGFFFNvkaa 90  Volvox carteri ...
XP_001730485  11 HY-AFLLLQNLPRASYVSIDQHAYR-TDTL-FEGFKLVPPGIHCLTWQSAGYaddr----qdaLATEGIRSALFLY---- 79  Malassezia glob...
GAC72603       8 DG-AVLLLNGLPARTQLVLDAHPQAyVTNDqFAGIKSLAPGWHCISWSLASEagnea-naggpSVEGSIRNVALRY---- 81  Moesziomyces an...
XP_012190670   6 AS-AKLLLQGLPPRTQVSLDAHPEVyLTNEhFAGIKSLAPGWHCISWSIASSelssnegsqavPATSSIRNVLLKW---- 80  Pseudozyma hube...
KIS71263       6 GS-AQLLLNGLPPRTQITVDAHSETyVINErFSGIKSLPTGWHCISWSIPSSdsstdqcasarPSEVSLRNVLLRW---- 80  Ustilago maydis...
CCF54578       2 AKnGMLLLNGLPTGSQFTIDSHTEAyLTNEqFAGIKGLPAGWHCISWSIASTqssfq--agavGVEGSVRNVLLRW---- 75  Ustilago hordei
CBQ70577       4 sK-GALLLNGLPPRTQLTLDAHSEAyLTNEqFAGIKALPPGWRCVSWSIPASdassn-eaagpS-QASTRNILLRW---- 76  Sporisorium rei...
EST06231       3 sAtATLLLKGLPGRTQLALDAQQDAyLNNEqFTGIKNLPAGWHCVSWSIATTssdd----tpgPSTGAVRNLLLRY---- 74  Kalmanozyma bra...
Q5KPA5        15 AG-GFLIITDLPEGSEFGIDGTFHT-VRK--FSGIKFLPPGFHFIAWSPPPSstt------agPSVIPIRQAFVRN---- 80  Cryptococcus ne...
EDN90691     171 DG-DVIIVGSLPPGSMFGYDTKAYTiKTEGtLEGVKNIPPGAHFFWGGS--------------ANG-SSRTGFWFMtmk- 233 Sclerotinia scl...
XP_002948987  91 pgkaageVSTDNVIVRKYDAAGELLVE-----------------------------LPDEEAQRYALGV-RryEFDWGLA 140 Volvox carteri ...
XP_001730485  80 -------TKEKDVLSRTYDPASDAWLTp----------------------------PGTDASTPLLVSRdHlqSMDKSLA 124 Malassezia glob...
GAC72603      82 -------FESQEIAIRDLDRIHQRLVVpnpdaassaar-------yramrvsrsynAGTSQQLQTVVSQeFlaSVQSRLL 147 Moesziomyces an...
XP_012190670  81 -------FDDDEISVRELDRTEERLIVpdqraspshaasgsaigrskhrrlsrtidPTSSPLEATLITPdVlsSVEPRLL 153 Pseudozyma hube...
KIS71263      81 -------FDDGETAVRELDRLQQTLVVpdqllscstavstssstrpkryrksramnASGVQTVSMLVTPeVlsAVEPRLL 153 Ustilago maydis...
CCF54578      76 -------FDEGEASVRELDRAQQRLVApdqlgsgssigr------skqfrtsrtfdPS-SKAISTIITLeVmnSVEPRLL 141 Ustilago hordei
CBQ70577      77 -------F-DDDVAVRELDRVQQRLVAshdtgigrsr----------rrhvtrtldPSSSRSIPTLVSPeVlaSVESRLL 138 Sporisorium rei...
EST06231      75 -------FDEGEVVARELDRGQQRLAVsgsgrstr-------------rrvsrtidPSASR-VATIVTPdVrgSVEERLL 133 Kalmanozyma bra...
Q5KPA5        81 -------FSAKERYAVHYDKDTENISL---------------------------------PENGTVISDdNlkTLDKELA 120 Cryptococcus ne...
EDN90691     234 ----lasDEYGDAHVLRWDNYHECLEEe----------------------------VSEAEKRIQKASI-PeiVNR--LE 278 Sclerotinia scl...
XP_002948987 141 PYNLHA--------------------------------WRQWRELTSCLD-------ERIIDAIQP--VGVNICTAAEAE 179 Volvox carteri ...
XP_001730485 125 PYPVDD--------------------------------YALWQSMTRYLQk-----sRATLARIFHvdAHTGDAMCDSFT 167 Malassezia glob...
GAC72603     148 PAPEEA--------------------------------QQRWRKATQHLGcaggaigRKVVARVVGidLESGDASTDSMT 195 Moesziomyces an...
XP_012190670 154 PYSVEA--------------------------------RELWRKATLHLSrdqgrvgRQIVARVLGvdASTGDSTTDSLA 201 Pseudozyma hube...
KIS71263     154 PYPEDA--------------------------------GHMWRQATRHLSldrggmgRQVVARVVGveIASGDFTTDSLS 201 Ustilago maydis...
CCF54578     142 PYPSAA--------------------------------RKPWQDALRHLSvdngrvgRKVVVRVLGvdVHSGDSNTDSLA 189 Ustilago hordei
CBQ70577     139 PYPSEA--------------------------------YEAWRNATRHLSlgggdvgRQVVAKVLGvdSASGDAMTDSFA 186 Sporisorium rei...
EST06231     134 PYPTTA--------------------------------GDSWRAATRHLSehgghvgRQVVAKVLGvdSE-GDSITDSLA 180 Kalmanozyma bra...
Q5KPA5       121 PYPFER--------------------------------FEAWKSLTSHIT-------PTILQSVIGpdGKVDGL------ 155 Cryptococcus ne...
EDN90691     279 PYlsntsvpspkpagsvstsptfvnfpsspiaaediygsdkWRHLTSCIK-------HPYLKRVTGgkwns--------- 342 Sclerotinia scl...
XP_002948987 180 LDEQDGGGggaggvegrprteaearlrqqllegrtarkaaaaaaaavqpppppaavpeapppppppppptaatsapgdrt 259 Volvox carteri ...
XP_001730485 168 SMSDREAR------------------------------------------------------------------------ 175 Malassezia glob...
GAC72603     196 SGPRRSNDpkeeeafqrtgnv----------------------------------------------------------- 216 Moesziomyces an...
XP_012190670 202 TGPSTAREitneetlshpgsts---------------------------------------------------------- 223 Pseudozyma hube...
KIS71263     202 TGPSRWNDakeeeqlqrttgal---------------------------------------------------------- 223 Ustilago maydis...
CCF54578     190 TGPSRARDgleqtsiqhtgnl----------------------------------------------------------- 210 Ustilago hordei
CBQ70577     187 AGPSRSADvkeeavlqrtgnl----------------------------------------------------------- 207 Sporisorium rei...
EST06231     181 AGPAQAADgkeetvlqqsgns----------------------------------------------------------- 201 Kalmanozyma bra...
Q5KPA5           --------------------------------------------------------------------------------     Cryptococcus ne...
EDN90691         --------------------------------------------------------------------------------     Sclerotinia scl...
XP_002948987 260 sgpsdmevedggggggggggglergtmhavaaaAVAARGTASvdngstSATEGGGMKSSTSSGRCF-------------- 325 Volvox carteri ...
XP_001730485 176 ---------------------------------------VNVhdlrhtYRSQMQGKASSPMSSVPSl------------- 203 Malassezia glob...
GAC72603     217 --------------------grnengitiwgnsQPAHSH---------VEVESDGEGSAEEATERIigaenrkrkrtenh 267 Moesziomyces an...
XP_012190670 224 --------------------grkedgkliwgksRP-QAEITE------VAVDGEDACAENDLAKsttrkrsfstel---- 272 Pseudozyma hube...
KIS71263     224 --------------------grkedgkliwgksRRLQAKTSE------VEVQDDMENGVEDAVEhksrkrsasies---- 273 Ustilago maydis...
CCF54578     211 --------------------grsengkiiwgksRPESEREALelfgvvAADDDEEKYDFAAKEEteskkrkrssptsn-- 268 Ustilago hordei
CBQ70577     208 --------------------grnekgkliwgksRPAPQPFE-------VTVDDEADDSAatsrkrttadpa--------- 251 Sporisorium rei...
EST06231     202 --------------------grrehgkvvwgksRPEAERFE-------VLADGDETDEGDPAqtskkrsnpds------- 247 Kalmanozyma bra...
Q5KPA5       156 ------------------------------------------------MPVIDQEEDTLTRDMREKleeikrrsq----- 182 Cryptococcus ne...
EDN90691     343 -----------------------------wkvsS-------S------HDIKTTELQATSaprdvkgnst---------- 370 Sclerotinia scl...
XP_002948987 326 --------------YSVVPRlVKEA-GLTAAQLTALNMDRSAQLEALAVNRWGGD------------VAAVVGEMQFAFV 378 Volvox carteri ...
XP_001730485 204 -------------aFTPFSLaHSWPpDAHGAERTRWSMDKSWLLEDVMSRACAAEhhgs-----slaHEPLLREFELSFL 265 Malassezia glob...
GAC72603     268 ategaeesddgvllFTEFDLrRSWPpNAVGAELTRWSQDKSWLLRDVAARARRGIasded--tqsgwYLPLLCEMELAFV 345 Moesziomyces an...
XP_012190670 273 ---tedadddeallFTSFDLrRSWPaRSIGAEITRWNEDKSWLLQDVTRRSHLGIaqsvn--retswYLALLCEFELAFV 347 Pseudozyma hube...
KIS71263     274 ---iegerddgqlaFTRFELrRSWPaNSIGAEITRWSQDKSWLLRDVARRSWLGIshsaysadgdgwFVGLLCEFELAFV 350 Ustilago maydis...
CCF54578     269 gktsgilddedsllFTTFDLqRSWPpNSIGADITRWSEDKSWLLQDVACRSRSSIsed-------dcYLPVLCEFELAFV 341 Ustilago hordei
CBQ70577     252 ---pssssdddslhFTPFDMrRSWPpNSLGPEITRWSQDKSWLLQDVARRSRTGIaqa-------qwYLPLMCELELAFV 321 Sporisorium rei...
EST06231     248 ----tedaddealhFTPFDLrRSWPpHSTGSDITRWSQDKSWLLRDVARRSSTGIippsl--eanneWSALLCELELTFI 321 Kalmanozyma bra...
Q5KPA5       183 -----nfgftkslmFVRFSLkKSWRdGAVGEEVTVYSKDKSWLLGNVIDEQLDRN------------PTALLGHLQLSFI 245 Cryptococcus ne...
EDN90691     371 -----nfdgddflnFVFPRNsRTFSdASTGRERTEQAIDSTAYIVEAIAN-Cty-----------edSDEIIGELQFCYI 433 Sclerotinia scl...
XP_002948987 379 AFVYGQSLQSFYQWRSLVTLFLNCEAAaLGGKSRHaa-----------------------tFAAFLAALRAQLACALAdt 435 Volvox carteri ...
XP_001730485 266 LFRCTNNAAALDHWAAIISLFCRAASY-LGAPAPHalhpcewdadrpasapmvtssshleaHLGWLEALVAQWQALPP-- 342 Malassezia glob...
GAC72603     346 LFVMASNVHAWDEWKDLLSLFCRAASI-IGSQSAFhlhpasidassaqlmdvdveqvrvdaHVAFLDTLAAQLDLLDG-- 422 Moesziomyces an...
XP_012190670 348 LFITANNAYAFDQWKDLIVLFCRSSSL-IGAQSAFqlhpsaatsmsd---fqndtavdltaHIAFLTTLHTHLLILPT-- 421 Pseudozyma hube...
KIS71263     351 VFITANNAYAFEQWMDMVALFCRASSL-IGAQSAFqlhpstqissp-----rtdrdihlnaHIAFLNTLHTHVFILPT-- 422 Ustilago maydis...
CCF54578     342 LFVSASNSYVWEQWKDLVALFCRSSTL-IGASSAFqvhpsqtgsps-----vvptqirldsHIAFLFTLRSQLALLQP-- 413 Ustilago hordei
CBQ70577     322 VFVTANNVYAYEQWTHLVALFCRSAEM-LGAQLAFqlhpahapapl----cavqaqpaldaHTAFLGTLRAQLLLLPR-- 394 Sporisorium rei...
EST06231     322 IFIAAGNGYAWQQWFDLVAVFCRSSSL-MGAQSAFelhpstt-------------ptdltpHIAFMSTLRAQLVLLPI-- 385 Kalmanozyma bra...
Q5KPA5       246 FFLQISSYSSLLAYQRILALLCQSSSF-LISPSTFlsppkrnpna-------hvgegmkiiYKELLKTLRVEIEALPD-- 315 Cryptococcus ne...
EDN90691     434 TGMVLGNLACMEQWGIIISKLFGAYRL-SMDHPVF--------------------------FRKVITAVHAQFMYDEE-- 484 Sclerotinia scl...
XP_002948987 436 adsaagvleskeDLVAA--ATHgsssllveevllagggRDCFLRRHLDSWFEVLRE-------------AEPGevdSRLL 500 Volvox carteri ...
XP_001730485 343 ------------HIWTDdlAS-----------------YEAPILDDLACLRANIGRslsaw----aamtSSTTtdhERLV 389 Malassezia glob...
GAC72603     423 ------------EFWSNqsTAK----------------EEQAVLKELDVLRANIARslalag--tvqaggGDEegrARLV 472 Moesziomyces an...
XP_012190670 422 ------------DFWSSqsTTQ----------------QETHLLKQLDVLRANIARslstps---qlqhkVDEahrEQLV 470 Pseudozyma hube...
KIS71263     423 ------------DFWSSqsTTQ----------------QESQLLKNLDILRANIARslstpc---hyqhtVDEdqrEQLV 471 Ustilago maydis...
CCF54578     414 ------------DFWSTqtSFA----------------EERAVLKELDTFRSNLARslsaasiqhtdpgAQLEekrEQMV 465 Ustilago hordei
CBQ70577     395 ------------DFWTTqtSPH----------------EESTLVAQLDALRANIARal----------saAREphaEQLV 436 Sporisorium rei...
EST06231     386 ------------DFWSTqeGK-----------------EEQTLLAHLDALRVNIARslsaaa---stgttKEEeqrQALV 433 Kalmanozyma bra...
Q5KPA5       316 ------------GVFDTelPE-----------------MDVFYLDQLESLRKNLASaiwge---veegtTWTElerQSFK 363 Cryptococcus ne...
EDN90691     485 -------------------GFDtsifdhd-------shlgddLKIILTKFKSRLNEqll-------sngSKITpeqEEVG 531 Sclerotinia scl...
XP_002948987 501 YEATQLRALLSRTVGWQFD 519 Volvox carteri f. nagariensis
XP_001730485 390 NAWRDLSSISHARFAWSLD 408 Malassezia globosa CBS 7966
GAC72603     473 AAWRKVSHLAASKFGWQLD 491 Moesziomyces antarcticus T-34
XP_012190670 471 KAWRSLSHTTASTFGWTLD 489 Pseudozyma hubeiensis SY62
KIS71263     472 KAWRALSHTTSSRFGWSLD 490 Ustilago maydis 521
CCF54578     466 TAWRTLSHLTASRFGWQLD 484 Ustilago hordei
CBQ70577     437 HAWRSLSHSCV-RFGWNLD 454 Sporisorium reilianum SRZ2
EST06231     434 QTWRALSHTTATAFGWQLD 452 Kalmanozyma brasiliensis GHG001
Q5KPA5       364 SLWNALRDSAWKKWKWDID 382 Cryptococcus neoformans
EDN90691     532 KAFEAFESWLW-KWGWDLR 549 Sclerotinia sclerotiorum 1980 UF-70
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