Conserved Protein Domain Family
MASE1

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pfam05231: MASE1 
MASE1
Predicted integral membrane sensory domain found in histidine kinases, diguanylate cyclases and other bacterial signaling proteins. This entry also includes members of the 8 transmembrane UhpB type (8TMR-UT) domain family.
Statistics
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PSSM-Id: 398759
Aligned: 25 rows
Threshold Bit Score: 127.531
Threshold Setting Gi: 81550483
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P77172  15 WGLPLFLPSLILPIFAHINTFAHISSGEVFLFyLPLALMISMMMFFSWAALPGIALGIFVRK---------YAELGFYET 85   Escherichia coli K-12
Q8ZNQ6  18 rLVSLGLVAFVFTLFSL--VLSRVGTQLAPLW-FPTSIMMVAFYRHAGRLWPGIAVACSLGSiga----slTLFPAASLN 90   Salmonella enterica ...
Q8P9T7   8 MAVAKELVRGMLISVCYCLAFLMLWRLSIDQWyLPVGLRVVTLLFRPYREWPFLLAGDAAAMlflriplgeLQGFNPLWS 87   Xanthomonas campestr...
Q8P646   1 MEGLKSVTQGLLTATAYCLAFQLSWHCSLDQWyLPAGLRIAALLLAPSRLLPWILMGDVAALlmirvpaisSVGVNPTWA 80   Xanthomonas campestr...
Q9KLQ9   6 PLIFAFVLYSISQFSLWNVSQYLSHNPLQAYLlFPTGLRLAVYLLARPTYVWVWLLSDMLLAgv------iLVLLPDQSS 79   Vibrio cholerae
Q7N8B5  10 LSLFLLIFYSLSWLALWTISFYLNDNGQQAALlLPQGLRLALFILLGRRYLPTLLATEITILl-------wLSSEQLITH 82   Photorhabdus laumond...
Q8ZN67  15 WGLPLILPSILLPVLSSANTYALTSTGNVVLFyLPLAFMLSLMLFFGWAALPGIVLAIFWRR---------YPQTGLYET 85   Salmonella enterica ...
P23842  15 TLAFTLTVVLIQLSRFISPLAIIHSSYIFLAW-MPLCVMLSILFIFGWRGVVPVLCGMFCTNl-------wNFHLSFLQT 86   Escherichia coli K-12
Q8ZN99  15 LLAFCLTVPAILLSRLISPRATIDSSYIFLAW-LPLCVMFSVLFLFGRRGVAPMVGGMMLTNe-------wNFHLPLPQA 86   Salmonella enterica ...
Q8YS17  14 LMISLLGLFALVIAHGM--ALIYRIQPGVSLWfPPSGVAIALTFWFGPCGIILTGLASFLMS---------PFWGLHGWE 82   Nostoc sp. PCC 7120
P77172  86 LSLTANFIIIIILCWGGYRVFTPRRNNVSHGdtrlisqriFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMPFNLGT 165  Escherichia coli K-12
Q8ZNQ6  91 FSWTAINIIEAATGAILLRKLLPSYNPLQNLn--------DWFRLAIGSAVIPPLLGGLLFWLI------APEAVASKAF 156  Salmonella enterica ...
Q8P9T7  88 YLSPFVHAPLIAGAIGLLRYQVPHIVKSQQW--------------FIPAALVIALWNAICSLVLNSTLGGPQAYPVLDLM 153  Xanthomonas campestr...
Q8P646  81 YASPWILVPAIALVPIAIRARYGAVHRAGAS--------------LIPMLLVTAVWGALCTLGTNIMLDGPSSAISGVKF 146  Xanthomonas campestr...
Q9KLQ9  80 PLMLLMPWVVWLAAVIARQHWPKLHLYWQKL-----------------LLIVALVLLHTILVGITFTLLAKPLHMGAETL 142  Vibrio cholerae
Q7N8B5  83 NIILLSPFLSLIPTFIVQQFWWRYPLYWQRLs-----------------------ILLAGVAANSVLQAICLGFTLTAGA 139  Photorhabdus laumond...
Q8ZN67  86 LSVTMHFIITIVLSWGGYRVFSPRRNNVSHGdahllfqriFWQVFCSATLFLVIYQFAAFVGMYESKASLMGVMPFNINT 165  Salmonella enterica ...
P23842  87 AVMLGSQTFVVLCACAILRWQLGTRWRYGLTsryv-wqrlFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDADAIFT 165  Escherichia coli K-12
Q8ZN99  87 MVLLFCQTFPVLLVCAIVRWQLGARWRYGIPnqgi-wlrvFWLGLMTPFGIKISMHLAGHYLAFPVTISTFFGTGTAIFS 165  Salmonella enterica ...
Q8YS17  83 RLIALVDIIEPLSAWLLYRRLWKGSRTINTLk--------DATLFTVSAPLVACATLAIIGSVCLVAIGKMPLASLSSNI 154  Nostoc sp. PCC 7120
P77172 166 LINYQALLVGNLIGVPLCYFIIRVVRNPFYL--------RSYYSqlkqqvdakvTKKEFALWLLALGALLLLLCMPlNEK 237  Escherichia coli K-12
Q8ZNQ6 157 LIWVLSEAIGALTLVPLGLLFKPHYLLRHRD--------PH--------------LLLETLLTLVITLALSWLAMR-YIP 213  Salmonella enterica ...
Q8P9T7 154 LRYWSGSYLGMLVLLLPAMLWANWNDGPVRL--------SL--QrdlaiavaviLSLFFLLGVSQEPLTRNILMVA---- 219  Xanthomonas campestr...
Q8P646 147 ARFAVGDYLGMLMVVLPVLLWMRRHDEETPS--------RLTPHcalavlatalIFALATLPQSNVARLGLM-------- 210  Xanthomonas campestr...
Q9KLQ9 143 IAVSIASLTGGIVLTPFLYLVADYLSHQTWH--------PLSPQlihhdvklkpKMLMWSLLFFSLGLLAELTLLE-QMK 213  Vibrio cholerae
Q7N8B5 140 SHLFLTSLTGGVLLSPFVYLIYEYLRQQHLK--------NM-LQpsdpdpqlrpSLLMWCCLFCLLGLSAQIFMSP-EIE 209  Photorhabdus laumond...
Q8ZN67 166 LINYQALLVGNLVGVPLCYFIIRTLRNPLHL--------RGYYQqlklqidskaTKKEIVIWLAVLTTLMFILCMPlTDN 237  Salmonella enterica ...
P23842 166 VVDLLSLFTAVLIYNMLFYYLTRMIVSPHFA--------QILWRrdiapslgkeKRAFTLSWLAALSVLLLLLCTPyEND 237  Escherichia coli K-12
Q8ZN99 166 IVDLLSLISAALIFTLFFYYPLRMIVSPHYM--------RIFWRrdvapylakeKRLFTLLWFATLATLLAVLCTPfETK 237  Salmonella enterica ...
Q8YS17 155 PHWWLGNAIGVMAIAPTALLVFTPYFQSQGWlhpteslnSGFVSqnfhpsrcllLEFSAILLLCLA--IATLTVAEtNQN 232  Nostoc sp. PCC 7120
P77172 238 STIFstnytlSLLLPLMMWGAMRYGYKLISL----LWAVVLMISIHSYQNYIPIYPGYTTQltITSS--------SYLVF 305  Escherichia coli K-12
Q8ZNQ6 214 ---Wp----fTCVIVLLMWSAVRLPRMEAFLi--fLATVIVVSLMLANDPTLLATPKTDVMvnMPWL--------PFLMI 276  Salmonella enterica ...
Q8P9T7 220 ------------MLVPMVVLTFRHGWKGSAL------GSLLASFAIEFSLPRVYQIGFFDQqvFSMQ--------LLYAV 273  Xanthomonas campestr...
Q8P646 211 ----------SLLIVPAVLLTWLHGWRGAAI------GVVLANTALAFSLRNTGVLGAYDSigFVVQ--------VMLAT 266  Xanthomonas campestr...
Q9KLQ9 214 PFAL------LIILLPTIFLAYRYGWQGGVLas-sLNCILLATARQFSGSFSSD---------QELL--------IFMSS 269  Vibrio cholerae
Q7N8B5 210 SLLV------ILIFIPNVFMAYRYGWQGGVLaa-lLGSLMITSARQFSGAFNDL---------GELE--------MFLTI 265  Photorhabdus laumond...
Q8ZN67 238 SSIFstnytlSLLLPVMLWGAMRYGYKFISI----IWAVVLITSIHYYQRYMPWYSGYDTQlaITSS--------SYLVF 305  Salmonella enterica ...
P23842 238 FIAG--------YLVPVFFIIFTLGVGKLRYpflnLTWAVSTLCLLNYNQNFLQGVETEYSlaFILA--------VLISF 301  Escherichia coli K-12
Q8ZN99 238 YIAG--------YLVPVLFIGFTIGVGKISYpllnFSWALTALFLLSYNRNFLQGVGSEYSlaFILS--------VLISF 301  Salmonella enterica ...
Q8YS17 233 GFKLqq--lsFLGFVPVLWAATRFGVTSGMLt--sSFCVLVTLFAY-----LVAYPKAMYLatFPVQaevlhvhkLSLLV 303  Nostoc sp. PCC 7120
P77172 306 SFIVNY----MAVLATRQR 320  Escherichia coli K-12
Q8ZNQ6 277 LLPANMmtmvMYAFRTERK 295  Salmonella enterica subsp. enterica serovar Typhimurium
Q8P9T7 274 TTTVLFv---FNARLREPA 289  Xanthomonas campestris pv. campestris
Q8P646 267 TATGLFv---LGARISSTL 282  Xanthomonas campestris pv. campestris
Q9KLQ9 270 QAFVGLg---LGIAISRQH 285  Vibrio cholerae
Q7N8B5 266 QALLGIg---LGIAISRQQ 281  Photorhabdus laumondii subsp. laumondii
Q8ZN67 306 SFIVNY----MSVLATRQR 320  Salmonella enterica subsp. enterica serovar Typhimurium
P23842 302 SVCLLY----MVRIYHRSE 316  Escherichia coli K-12
Q8ZN99 302 SICLLY----MARINQRSe 316  Salmonella enterica subsp. enterica serovar Typhimurium
Q8YS17 304 QCAVSLf---VGIAITERS 319  Nostoc sp. PCC 7120
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