Conserved Protein Domain Family
CHASE4

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pfam05228: CHASE4 
CHASE4 domain
CHASE4. This is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in prokaryotes. Specifically, CHASE4 domains are found in histidine kinases in Archaea and in predicted diguanylate cyclases/phosphodiesterases in Bacteria. Environmental factors that are recognized by CHASE4 domains are not known at this time.
Statistics
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PSSM-Id: 398756
Aligned: 150 rows
Threshold Bit Score: 40.393
Threshold Setting Gi: 123510743
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
PRJNA229194:W911_12130   42 INKSVGSVLDGLKSVAWWDEAVtRIGGDtVDLHFADTEFGLFLTETYGHDEVYVLDGNDRPIY----AYKNGARAepgay 117  Hyp...
BAJ63914                 53 IEQEQQNLQTLVLDFTFWDELV-KFAEY-PDEAWAKNILLP-SMEVFDVDCLWVYSPQNELIYqnqervctlya------ 123  Ana...
jgi:Cyan7425_3556        59 IKLKGESLENFVHNYTYWDELI-QFTKA-PDPKWARDQLEA-SMPSFKLDGIWVYNLNKKLVYatvnrsspsnppalpl- 134  Cya...
jgi:Cyan7425_3504        53 IKLNSKSLTNFTYDYSYWDEMV-KFVQT-KDSLWARENLQV-VMPTYNLNAIWVYDQSGKLIYhttnlsdrhnqiqhiip 129  Cya...
WP_014204540             58 IALEKQEMGASMADYAAWNDLA-EYIAD-PDPEFIEDSIGIHAFQSKALDGIFIFTPDEQLVWgmkydfeqrkvgdyqsf 135  Vib...
Q9KPS7                   58 LSLERKAMGASLADYAAWDEMA-DFIAK-PTLEFTQSNIGEHAFSSQFLDGVFIYDPEGNLVWgkkydaatgqsssyehl 135  Vib...
jgi:Sama_2608            53 MNFFSQPLSTFSHDYGVWDEMV-DFIQS-PDPEFIESNLYDDAFVAAGMDGAFLFDTNGKLVWgyqgvpgllpdsldsqp 130  She...
Q07W08                   53 LSLSKNSLTTLCYDYAVWDELV-EYVGN-PTDDFVQSNMPNNAFEAANIDAVFVIDTNNKLIWdyqddslkssrsslvhl 130  She...
jgi:Shew_2953            53 IAYAQKNLDTLCYDYAIWDDMV-SFVDN-VSPEFVTKNLFDNAFEAANVDGFYVFNRQNQLVWqyrsgadfdsqqlplgk 130  She...
BAJ63159                 53 vqriyGEMTTLAKDWALWDESY-TFLKG-QNPTFTEENFHPQALRSISIDLVVLSDTGGLIRFaqhyDQESERYVpvtts 130  Ana...
PRJNA229194:W911_12130  118 dlrraelspvvaevrgrpedsglkerpdefgrtqsdyrtlsPAADIArwaghivTVGDRP-------AVVGAISIv-PN- 188  Hyp...
BAJ63914                124 -------------------------------phlfkkpenlFQHGAFikf-tewQANAPA-------ISVYGASIhpSEd 164  Ana...
jgi:Cyan7425_3556       135 -------------------------pdrdlvaflqllhrqrFAHFFV-------QTPQGL-------LEVRAATIhpSDd 175  Cya...
jgi:Cyan7425_3504       130 -------------------------dlqrfkqflellhkkrSQHFFI-------YTTNRL-------FEISAVTIhpTSd 170  Cya...
WP_014204540            136 lp---------------------yfpiilsepkrasrdyveAKVRFV-------VVGQEP-------FLAATSRV--CNs 178  Vib...
Q9KPS7                  136 lp---------------------dfsrilqqatrlsvdeisTSVRYM-------VVEDEP-------YLAATARV--CDs 178  Vib...
jgi:Sama_2608           131 a----------------------wigpvlpdaktvstesasTRRGII-------RYGSRV-------MFFSNSNV--LPs 172  She...
Q07W08                  131 fhqq-----------------ntesfailptaaeiasqtvsSRSGYL-------VFDGAL-------IYFSNTTI--LPs 177  She...
jgi:Shew_2953           131 vg---------------------vagkllpskvevdtgkpsVRSGLL-------RMGSRV-------VYFSNVTV--LPs 173  She...
BAJ63159                131 ------------------------------------lqayvGKEGAFwrwldsrESTERLivadghvYFVTAVPV--LRt 172  Ana...
PRJNA229194:W911_12130  189 ---IEM-ALLKGtpkLLVGVVYIKEEFISKIaRSILLSDLELS 227  Hyphomicrobium nitrativorans NL23
BAJ63914                165 vahQ---TPPRG---YFFVGRIWNTERLQNL-NKLSNLEVTVS 200  Anaerolinea thermophila UNI-1
jgi:Cyan7425_3556       176 ---PEHrTAPQG---YFLAGRLWSKQFLTHL-GSMVHAQIELL 211  Cyanothece sp. PCC 7425
jgi:Cyan7425_3504       171 ---PERkTPPQG---YLIASRQWSKAYISTL-EDLISSQIIIQ 206  Cyanothece sp. PCC 7425
WP_014204540            179 ---EGT-ACDKG---YLIFVKKVRSQFANVI-ELATGIDIdvl 213  Vibrio furnissii
Q9KPS7                  179 ---DGK-GCNKG---FLIFIKKVRAQFANVV-EQATGVDIEVL 213  Vibrio cholerae
jgi:Sama_2608           173 ---NGH-GKVIG---SFMVVRLINVSLTDML-KELTLVESSLS 207  Shewanella amazonensis SB2B
Q07W08                  178 ---TGH-GEIAG---SLTMVRLVDKALINDI-SQFSLVKFSIE 212  Shewanella frigidimarina NCIMB 400
jgi:Shew_2953           174 ---NGE-GEVAG---SLLTVRNVSQAIHEEI-EQFSLIKFDLE 208  Shewanella loihica PV-4
BAJ63159                173 ---SGE-GPAAG---LLLFGREINEQLLDQI-RVNSGVAVEFY 207  Anaerolinea thermophila UNI-1
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