Conserved Protein Domain Family
CHASE2

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pfam05226: CHASE2 (this model, PSSM-Id:428378 is obsolete and has been replaced by 428378)
CHASE2 domain
CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria. Specifically, CHASE2 domains are found in histidine kinases, adenylate cyclases, serine/threonine kinases and predicted diguanylate cyclases/phosphodiesterases. Environmental factors that are recognized by CHASE2 domains are not known at this time.
Statistics
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PSSM-Id: 428378
Aligned: 396 rows
Threshold Bit Score: 43.4528
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Spiaf_1512         24 VCLLvLllqfTPLVSR-------LETMVLDAHFHwrYRf-----dAagsvregvtfraqnpnvhpdILIIGVDNNALnr- 90  
PRJNA194094:J421_5797  18 VACAlV----GALRETral--epAGLWAYDALLRrippd-ttpvpH--------------------VAVARITERDLrr- 69  
WP_012599767           16 ITGF-I----LVLRTLgwl--qlFELLAYDILFQ--LRp------Lepl--------------dsrIVIVGLQESEIq-- 64   Gloeo...
CCD03787               14 aAVFaV----LLMHLLgwl--qpLDLLAYDNGLK--LRarpavddR--------------------IVLVGAREADLaa- 64  
WP_015110258           35 AAALlL----LALQRSpvn--etLNLLLYDLITS--LRpappgtdKp-------------------ITIIGIDESDLat- 86   Cyano...
CAK24820               16 AAIVvL----VLLRSTdla--qtLDLVIYDLITS--QRsegsgqdQp-------------------ITLVGIEESDIqr- 67  
jcvi:TREAZ_0448        19 ALVLsAvlgaLGLFAT-------IDRGIYDLLLSakIRyfpla-------------------lnsqIIHADLSDSSEvrl 72  
Q027H2                 21 aSFAlAlftsYILGSQ-------LNIWAYDAMYRayRPpai----------------------qpeSVVLAIDELTLvqc 71   Candi...
wustl:cce_4928         24 LISL-I------CRYAgfw--qeNELYFFDQMTQ--KTa------Pslt--------------qnrVVIVKITEEDVkt- 71  
jgi:Cyan7822_5897      19 ISMW-L----LLANFMpifsfpsIELTLYDWLAA--NKgeml--------------------hsraITLVGLTATDWl-- 69  
jgi:Spiaf_1512         91 ---fGRWPFDRRIHGNFVNNLariQNQdaRERALFLDFffsepasnptdDAMLVHSM--RQsgrvflenvltfdpprtqd 165 
PRJNA194094:J421_5797  70 ----agWPLADSTVEMVARRL---ASL--GARVVAFDVy----------RERVPPAI----------------------- 107 
WP_012599767           65 ----KYYPLSDQTLAQLIEKI---KRQ--NPVAIGLDFyrdvs--vgagQEQLLKTF--KT------------------- 112  Gloeo...
CCD03787               65 ---lG-WPLSDGQLADLLKAL---SAA--KPAAIGVDIyrnwp--igdgQGELERML--RE------------------- 112 
WP_015110258           87 ---yG-FPIDDRVLCEAIDRL---SAG--GAVAIGLDIyrdqg--vgpdQACLRQRF--RT------------------- 134  Cyano...
CAK24820               68 ---fG-WPIDDGIFCDAFDAL---NAS--GVTAIGFDIyrdqg--vgaeQQCLRDRF--RE------------------- 115 
jcvi:TREAZ_0448        73 geslGS----RGAFADFLNVL---GS---YNARVAFDFifrt---paaeDAAFAEAArsASlcimaiapvemeyanfayd 139 
Q027H2                 72 gg----irgiRRPIAEALRIL---APA--KPKVVAIDViladk-gdevgDAALSAALhaTPnlvlstelidgdr------ 135  Candi...
wustl:cce_4928         72 ---fPAFTPDDRTLARTLKNI---AQQ--KPRAIGLDMvrdip--vppgSNELKAVF--EN------------------- 120 
jgi:Cyan7822_5897      70 ---eYGNPVEDQVIANTLKII---ERY--QPAFIGLNFwrtrk--hgegHEELLQIL--AQ------------------- 118 
jgi:Spiaf_1512        166 yqtffrRqhalqntaGTItdvsgdwqnmlsfqgveaplipygnaV----------------------RGYGHANFi---- 219 
PRJNA194094:J421_5797 108 ------AaagsaiggTAV--------------------------Vfasklasardg-gfpcpigsseDACGFADAv---- 150 
WP_012599767          113 ------T--------PNLigvkk----------------aigekVnppqa-------------lkerGQIASSDVv---- 145  Gloeo...
CCD03787              113 ------N--------PDI--------------------------VwvnrqpseaggaiaapsvlatpDRIGFSDIl---- 148 
WP_015110258          135 ------N--------PRL--------------------------Vsiinvaeai-----gpvpgtppDRQGFNDLv---- 165  Cyano...
CAK24820              116 ------E--------PTL--------------------------Vsifnvaagi-----gavpgtpiERQSYNDLs---- 146 
jcvi:TREAZ_0448       140 sltseeK--------ALLssnvwhirehgknnip-----------------rartfilsdypissaaAELAHIGVl---- 190 
Q027H2                136 -------------------------------------------------------iwedprpefmgkAKLGHVSAv---- 156  Candi...
wustl:cce_4928        121 ------T--------SNLygig------------------kftgIegdpfft---------yiappyT---LDNLqrvgd 156 
jgi:Cyan7822_5897     119 ------Y--------TNIvgsqwk---------------ealsiIeppep-------------ltipGRTGDVTVl---- 152 
jgi:Spiaf_1512        220 ----aDnDE---V-----FRRqplvakiseVVAlYDIHellqdqsvdllqyqrlawldrfgeqhtielplteqggqqlld 287 
PRJNA194094:J421_5797 151 -----------aArgsptLRR---------ALYhVQLAgdsa-------------------------------------- 172 
WP_012599767          146 ----lDgDG---V-----LRR---------GLIgFFDEqdq--------------------------------------- 165  Gloeo...
CCD03787              149 ----vDpDG---V-----VRRs--------LLFlEDPSgqhat------------------------------------- 171 
WP_015110258          166 ----lDaDG---V-----IRRd--------LVHv---Agqde-------------------------------------- 184  Cyano...
CAK24820              147 ----lDgDG---V-----VRRd--------LVHv---Tgqde-------------------------------------- 165 
jcvi:TREAZ_0448       191 ----pDsDG---V-----YRRt--------PLFyrwed------------------------------------------ 208 
Q027H2                157 ------pDKedmV-----TRK---------ILLyQHSAreq--------------------------------------- 177  Candi...
wustl:cce_4928        157 vsvvvDdDG---V-----VRR---------ANLfPTTGesa--------------------------------------- 180 
jgi:Cyan7822_5897     153 ----yDrDQ---V-----IRR---------FTLySPSEnfpdekefn--------------------------------- 178 
jgi:Spiaf_1512        288 sleergapytredgsssyrirlfqdhfvpSITLSLALeymnv--------------gihdIevvlgshiLIrepQmyVpa 353 
PRJNA194094:J421_5797 173 --------------------------praSLAYTAVVryvapd--------------------vldtsaEPrlgRwrFap 206 
WP_012599767          166 --------------------------yvnTIGAKLGFlylerkgifpe--tdksqkaikvG--------EKifeR--Fqa 207  Gloeo...
CCD03787              172 -------------------------alsmVMALRLLghrgivpqsdpee---------------pehmrlgaatlrpVea 211 
WP_015110258          185 --------------------------aivsLPLRLLElgrgqrslrqr-------------------ldagrepgpwLep 219  Cyano...
CAK24820              166 --------------------------atvaFPLRVLEvatgdrslrda-------------------ldagtnagpwLsa 200 
jcvi:TREAZ_0448       209 -------------------------glipAISLAVAVrelgi-------------------------------------- 225 
Q027H2                178 ---------------------------rgALALEAFLls----------------------------------------- 189  Candi...
wustl:cce_4928        181 ---------------------------ipSLGLLLAEkylenegispeggtnnrlklgkvE--------FPifnQn---- 221 
jgi:Cyan7822_5897     179 --------------------ktaqynyirSLPWELARrfllaqgvkiieptks-----spllleypngkmiklqP--Lqd 231 
jgi:Spiaf_1512        354 edswqpfQ-VMdrpprynrdgeltrearyrqvdeLRIpidahgqmliNYVgPrssssaqgiqtfpvrsyagyasritGpD 432 
PRJNA194094:J421_5797 207 m---qgrE-GDyvrdp-------------ivgheELL----------DLHrG-------------------------ApR 234 
WP_012599767          208 ------nQ-GAyrqad-------------aggyqILL----------NSRnPr-----------------------qSfV 234  Gloeo...
CCD03787              212 -----tdG-GYagvda--------------rgyqFLL----------DYAlGpg----------------------pI-R 238 
WP_015110258          220 -----asG-GYdqlda--------------agfqQML----------SFH-Rig----------------------sF-H 245  Cyano...
CAK24820              201 -----daG-GYhneida------------glglqRLL----------RFR-Epr----------------------sY-A 228 
jcvi:TREAZ_0448       226 ------------------------------------------dpsaiEFYpGhclvlplsgdeairipvdescsaliPfT 263 
Q027H2                190 ------rGvATpresleftalrgglasaelqvgdVTIpvledkrekrRFMrVh------------------------FfP 239  Candi...
wustl:cce_4928        222 -------T-GGyirad-------------dggyqTLM----------RWIrp-----------------------lqQfK 247 
jgi:Cyan7822_5897     232 w----lgK-MSysqwg-------------nrgfqQLI----------HWPsq-----------------------nfEfP 260 
jgi:Spiaf_1512        433 PytwpatMAL----------------------ENKIVMAGAFAt-GMADdeQATPFG---------MMY--GVEMHANAL 478 
PRJNA194094:J421_5797 235 V------LTFdldalsrg-------rvprawvAGRMLFVGYDAa-SIRDe-VYLPTTdpdr--qppGEP--GAFYHALAA 295 
WP_012599767          235 K------VSFgdvlseq---------inprlfQDKLVFIGTTSs-SIKDe-FLTPYSrslf-tspqPVY--GVEIQANLA 294  Gloeo...
CCD03787              239 D------FSVrealegr---------vpaealAGRLVFVAVTAd-SVKDy-FRTPVdsgfa---------fgavVHAQAT 292 
WP_015110258          246 L------WNLqdvlgrr--------pipadqiRGHIVLIGSTAp-SLRDl-FPVPhtrsalgarqlLVP--GVEIHAHRL 307  Cyano...
CAK24820              229 T------YTLaevidgt---------vpntmlRDRIVLIGSTAp-SLRDl-FEVPhtrfargdslfTIS--GVEVHANRL 289 
jcvi:TREAZ_0448       264 AtwadddYRIsferiagaahdeelytslfselSGSMIMAADTTt-GKRDf-GITPGEt--------VYPlsG--IHTAVL 331 
Q027H2                240 PgstvpiVSMrrllddp---------slaaqfAGKVVFIGVTAnsEVQDr-LFTPVG---------RTA--GIEINAAAF 298  Candi...
wustl:cce_4928        248 Q------ISLtevyenr---------ipvnffQDKIVLIGYWTtsQKRDl-FYTPFSeqgdgktprqAF--GVEIQANFS 309 
jgi:Cyan7822_5897     261 L------VSFhdvlsyr---------vppdffHNKIILIGGASn-RVADi-YSTPYKingd-rfraTRY--GLELMAIAT 320 
jgi:Spiaf_1512        479 NTIL--------------MdnfLHPVSFWHNLMVLlaltmLTAWV 509 
PRJNA194094:J421_5797 296 SQAAdltlg--------ggsvlRVRTLPDWGEWIA-----LAAGC 327 
WP_012599767          295 SYILsavf-------dnrA---TIKTFPPLIDLIF-----LIGig 324  Gloeothece citriformis
CCD03787              293 GQLLrmalgea-tptanlPdwaE---------LAV-----TVAVG 322 
WP_015110258          308 AGLMeryvagdprrlrtlPgwvE---------RLA-----EVVAV 338  Cyanobium gracile
CAK24820              290 ATLIderngsf-qqgwliPgwgN---------LLL-----VIGFA 319 
jcvi:TREAZ_0448       332 SGIMee---------------yFYAPWSFAAKLGT-----LAVFL 356 
Q027H2                299 ETMA--------------HrlfFTDVTPIQEDLIVlallaAIGLA 329  Candidatus Solibacter usitatus Ellin6076
wustl:cce_4928        310 EYILhtvl-------dglP---PLKSLPEGLEIIW-----LTGWG 339 
jgi:Cyan7822_5897     321 LNLLsle--------vqkP----TLIPSGLINYLW-----IAFWV 348 
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