1Q2L,3E4A,3HDI,1HR6,6GIQ,1HR7,6OFT,1Q2L,3E4A,4NNZ,2FGE,3S5M


Conserved Protein Domain Family
Peptidase_M16_C

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pfam05193: Peptidase_M16_C 
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Peptidase M16 inactive domain
Peptidase M16 consists of two structurally related domains. One is the active peptidase, whereas the other is inactive. The two domains hold the substrate like a clamp.
Statistics
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PSSM-Id: 398733
Aligned: 134 rows
Threshold Bit Score: 49.7022
Threshold Setting Gi: 3915964
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1Q2L_A 658 SITLKEVLAYRDALKSGARPEFMVIGnMTEAQATTLARDVQKQLGA-----------DGSEWCRNKDvvVDKKQSVIFEK 726  Escherichia coli str...
O25656 198 NWTLKDIKKFHSLYYQPKNAIVLVVGdVNSQKVFELSKKHFESLKNldekaiptpymKEPKQDGART---------AVVH 268  Helicobacter pylori
4NNZ_A 171 RMTIDDLRHWYESWYAPNNATLVVVGdVTADEVKTLAKRYFGEIPWr----------QLPPARKPLElaEPGERRLKLYV 240  Pseudomonas aerugino...
Q9A579 219 AASLDDVKTWFKNYYGPANATLVLAGdISAAEAKAKVEKYFGDIA------------SGPPVTRQKEwiAKRTGSQRAEM 286  Caulobacter vibrioides
Q9RTZ9 246 NVPIGNLKAFYKTYYQPDNAVVTLAGnFDEGQALTLIADSYGKVRRp---------wRTLPRQYTEEnpQDGERSLTVRR 316  Deinococcus radiodurans
Q9A2H7 210 AATVDDVRAFHRTYYRPDNAALIIVGnFDQTKLDAMIDKYFGSLTTp---------aGAIPKVTAVEpaRTGPKTVNTYG 280  Caulobacter vibrioides
P74305 274 NLSRQDVTDFYEKYYIPGNMTIAVVGdVKVDQVKSLAQKYFGRFP------------QRPPTPQVTVvePPQTQQKEINL 341  Synechocystis sp. PC...
P55679 251 QLNREDALKFYDRYYAPNNAILVVAGdVDAGRVRQLADETFGTLPRg---------pDLPARVRPQEpeQNTKRIVALTD 321  Sinorhizobium fredii...
O67308 184 KFTREKLLKFYKSFYQPRNMAVVIVGkVNPKEVEEEVMKTFGKEEGr----------PVPKVQIPTEpeQIGIRFKKLKD 253  Aquifex aeolicus
P73670 182 NYTANQLRCFHRTHYQPENMTVVMVGdIREKAAIAYMEEIFDHFGVrsecppttrlpNHPIQTIKRE-------TLRIPE 254  Synechocystis sp. PC...
1Q2L_A 727 AGn--STDSALAAVFVPT-----GYDEYTSSAYSSLLGQIvqpWFYNQLRTEEQl---GYAVFAF-PMSVG----RQWGM 791  Escherichia coli str...
O25656 269 KDgvhLEWVALGYKVPAFk----HKDQVALDALSRLLGEGkssWLQSELVDKKRl---ASQAFSH-NMQLQd--eSVFLF 338  Helicobacter pylori
4NNZ_A 241 RTq--LPNLIMGFNVPSLgssenPREVNALRLIGALLDGGysaRLASRLERGEEl---VAGASTY-YDAFNrg-dSLFVL 313  Pseudomonas aerugino...
Q9A579 287 QDrvpQTRIYKVWNTPGFg----AAETDYLDLLSDVLVSDktsRLYKRLVFTDQs---ATAVGAS-VSPSEi--gGQFIV 356  Caulobacter vibrioides
Q9RTZ9 317 VGd--AQYLIVGYHIPSVr----HPDAAALQVLGELLSDEpsgRLYQALV-QTGq---ATAAGSI-TNPGSd--pGLATY 383  Deinococcus radiodurans
Q9A2H7 281 PNv-pLPALAITWLAPAAa----DKDAPALAVLDAILTAGkssRLYDSLVYDQKi---AQSVFSS-APNNAq--pGLFYV 349  Caulobacter vibrioides
P74305 342 TLp-sQPWYFEGYHSPAFd----DPDSAVFDVMTTILSSGrtsRLYQSLVEEKQlalmAQGFNGFpADKFP----NLLMF 412  Synechocystis sp. PC...
P55679 322 PRv-tVPSFQKSWVTTSYgt-aeQGEAEALDILSEILGGGtrsRIYQELVVKQAi---ASSGGAY-FNgrsldpsSFTVF 395  Sinorhizobium fredii...
O67308 254 PRi-eKAYWIIGWRVPAIg----KTDYKGLLVFSEILCGGrisVFYRELR-EKGl---VYSYSCG-DMGRPr--dNIFII 321  Aquifex aeolicus
P73670 255 LG---PSRLTMGWNGPGId---rLQDNIGLDLLAVVLAGShcaRLVQRLREELGl---VFDIQSC-FSLQKe--aSLFTI 322  Synechocystis sp. PC...
1Q2L_A 792 GFLLQSNdkqpsFLWerYKAFFPTAEAKLRA-MKPDEFAQIQQAV 835  Escherichia coli str. K-12 substr. W3110
O25656 339 IAGGNPNv---kAEAl-QKEIVALLEKLKKGeITQAELDKLKINQ 379  Helicobacter pylori
4NNZ_A 314 SATPNVQkg-ktLEQv-EAGLWKQLDDLKQNpPSAAEIERVRAQM 356  Pseudomonas aeruginosa PAO1
Q9A579 357 TLTVKPGg---dPAAv-EKAFDEEFQRLLRDgPTPEEVAKVRTNN 397  Caulobacter vibrioides
Q9RTZ9 384 VAILGKDd---dLQKa-QATLLSTLENAAKTpFTEEEVARVRTRV 424  Deinococcus radiodurans
Q9A2H7 350 GAIMAGGk---tVAQg-EAALRAQVARVRDGlVTPAELAEAKAGL 390  Caulobacter vibrioides
P74305 413 YAQSAPGr---sLDDl-SEALHGEIERLKMEpVTPEELERAQNLL 453  Synechocystis sp. PCC 6803
P55679 396 GSPRGEAk----IEEv-EDAIDAEIRKIIEFgITDVELEKAKNRF 435  Sinorhizobium fredii NGR234
O67308 322 TATFPPEn----YEKv-KKRVFELLKETYEN-LTDEQVEEAKSRI 360  Aquifex aeolicus
P73670 323 NAYLTSAq----AERv-EAEICAAIQTLQTTpISTAELARAQRLL 362  Synechocystis sp. PCC 6803
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