5WOL,5U5I


Conserved Protein Domain Family
DapB_C

?
pfam05173: DapB_C 
Click on image for an interactive view with Cn3D
Dihydrodipicolinate reductase, C-terminus
Dihydrodipicolinate reductase (DapB) reduces the alpha,beta-unsaturated cyclic imine, dihydro-dipicolinate. This reaction is the second committed step in the biosynthesis of L-lysine and its precursor meso-diaminopimelate, which are critical for both protein and cell wall biosynthesis. The C-terminal domain of DapB has been proposed to be the substrate- binding domain.
Statistics
?
PSSM-Id: 398714
Aligned: 594 rows
Threshold Bit Score: 62.4712
Threshold Setting Gi: 355396563
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
5WOL_A        111 AVLMMKYAKEAAHYFPdVEIIEMHHSQKIDAPSGTAIKTAQMIGemrsskk---------depfkdrA-RGEikN--GIP 178 Coxiella burne...
XP_006606094  139 sillQQAAISASFHYSnVEIVESRANAN-DLPSADANQIANNLSnlgqiynr-------edpstdvlA-RGQvlGd-GIR 208 soybean
EEF51441      169 siLLQQAAISASFHYNnVEIVESRAHGA-DLPSADANQIAKNLSnlgqiynk-------edlstdvlA-RGQvlGedGVR 239 castor bean
Q04FS0        121 AVLMMYFSGIAARFMPnVSIEEIHHPDKLDAPSGTARITAGILAdngastkt----------vstsadgDKNiiE--KVL 188 Oenococcus oen...
EHN59744      122 AVLMMYFSGLAAKFMSnASIEEIHHPDKVDAPSGTAKMTAAILAqagaatakp------ddrrldgqS-QSNlvD--GIQ 192 Oenococcus kit...
Q03YE1        112 AVLLMQFSQLAAKYFPdAEIIEAHNPKKVDAPSGTAKQTARLIAkariaep---------tstklapA-RGEqiD--RVP 179 Leuconostoc me...
B0RGX5        109 SVLATSFAQMAARFYDsIEIVEAHGASKIDSPSGTAVRTAELMSqargsrgpv------qaphtdqrA-RGQqvA--SIP 179 Clavibacter mi...
Q0K6F4        132 VVLLQKFAEMAARHLEhWEIIDYAKAGKIDVPSGTVRELAYRLGqvkaaaqav-----pvdqvkgpkEtRGAtmS--GTQ 204 Cupriavidus ne...
WP_014746541  135 AALATRFSLIAARYIPhVEVVEIAGPAKPDAPSGTARELAERLGrvarpempqgtvpvapgkvlgdpAlRGGtiG--GVQ 212 Tistrella mobilis
jgi:Tlie_0251 131 IYLVTKFIREARKFFPfVSIIDKHTNKMANAPSGTAAALAKAASegkmge------------------------iesket 186 Thermovirga li...
5WOL_A        179 IHSIRLPGLFSH---------------QSVIFGSNGETLTIRHDG-MDRNCTMPGIFMACRKvm-eLDYlVYGLENLL 239 Coxiella burneti...
XP_006606094  209 VHSMVLPGIPSS---------------TTVHFSGPGEVYSIKHDI-TDVKCLMPGLLLAIRKvv-rLKNlVYGLEKFi 269 soybean
EEF51441      240 VHSLVLPGLPSS---------------TTVYFSKPGEVYSIKHDI-TDVQCLMSGLLLAIRKvi-rLKNlVYGLEKLL 300 castor bean
Q04FS0        189 ITSKRKKDYVAY---------------QSVDFVNEYETLSISQNS-LDRKSFMPGVELAIKKan-qQQGlVVGLDKIm 249 Oenococcus oeni ...
EHN59744      193 IISKRQAGYVAY---------------QSVNFANDYETLSIAQNS-LDRKSFMSGVQLAIKNad-qQTTlLVGLDKMm 253 Oenococcus kitah...
Q03YE1        180 VHAVRLPGYIAQ---------------QSVYFGGVDEQLTLTQST-TSRSAFVPGVIRAIEAvk-nIDGvVIGLDqii 240 Leuconostoc mese...
B0RGX5        180 VHSLRMQGVVAK---------------QDVVFGGNGEVLTISHDT-LAPSAYEAGILLALRAtr-tARGvVVGLdrli 240 Clavibacter mich...
Q0K6F4        205 VHAVRLPGYQLG---------------VEVIFGADGQRLHLKHEAgDGSTPYVAGALLAIRKvh-tVRGvVRGLDKVm 266 Cupriavidus neca...
WP_014746541  213 VHSLRLPSYAAS---------------IDAHFAVAGARLVISHDAgKDAKAYVDGTLLAIRKva-gVTGlVRgldvll 274 Tistrella mobilis
jgi:Tlie_0251 187 YPGVLGGKIEGVqvlsqrlpwpgpysgHEITLARKDEIIKISVED-YTSDIYMDGVFLTARKikespRG-VFyrslee 262 Thermovirga lien...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap