Conserved Protein Domain Family
T2SSE_N
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pfam05157: T2SSE_N 
Type II secretion system (T2SS), protein E, N-terminal domain
This domain is found at the N-terminus of members of the Type II secretion system protein E. Proteins in this subfamily are typically involved in Type 4 pilus biogenesis, though some are involved in other processes; for instance aggregation in Myxococcus xanthus. The structure of this domain is now known.
Links
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Statistics
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PSSM-Id: 428339
Aligned: 100 rows
Threshold Bit Score: 45.4036
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q55799                           19 LIE-AGYLSlsqihqalmearrtgialptlvetilgeslpdelhrqyQAQQRFALSVI---------------------- 75  Synechocystis sp. PCC 6803...
Q988B0                            1 MTE-LGLIG--------------------------------------EQELASSLSRY---------------------- 19  Mesorhizobium loti...
WP_012173965                     70 MVS-MGLSRadtev-----------------------------geldEDAVFQALAEE---------------------- 97  Desulfosudis oleivorans...
Q08WC8                            7 LVH-NGALT--------------------------------------PEQVETALAYQnrwrckfgqavlelnmiprepf 47  Stigmatella aurantiaca DW4/3-1...
Q83M21                          522 MLM-QGLIS--------------------------------------AEQLAQALAEQ---------------------- 540 Shigella flexneri...
CGS-ASRI:complete_CGSHiGG_04305   1 MTS-YALLH-----------------------------------------TQRVTAKN---------------------- 16 
EDM28112                         30 LLE-SGELS--------------------------------------EERLINAFAQE---------------------- 48 
jgi:M446_1171                    66 LTE-LGLVH--------------------------------------ETTLVTALAEA---------------------- 84 
EDL57406                         34 VME-MGLAS--------------------------------------EEDLLKAFADE---------------------- 52 
WP_011831773                     22 LREkNAVTD---------------------------------------QQLAVALAKQralaetgerag--------lce 54  Methylibium petroleiphilum...

Q55799                           76 -------HGVKFfdq--hqlTTLANTEAIASLLNRyFPLPICRQYGFLPLHyrENP----GALLVVMVDPSD-PEASQFL 141 Synechocystis sp. PCC 6803...
Q988B0                           20 -------LEAPM--------PVEIPEQVSPEMLAS-VPLAYLRENAILPLQ--MDA----ERLVVAVADPFS-SATIDAL 76  Mesorhizobium loti...
WP_012173965                     98 -------WDVPF--------KKIDPLKLDLELVTNtIPRSFAMNYLSLPIA--VEN----GELIVATPNPFN-TTVMDDI 155 Desulfosudis oleivorans...
Q08WC8                           48 lrllaghLKVAF--------IRPEQIDKVPATTVRrLRADVLSRLRVCPLR--FEQvgtrGSVYLATHQPEN-LQLLDEA 116 Stigmatella aurantiaca DW4/3-1...
Q83M21                          541 -------NGVAW--------ESIDAWQIPSSLIAE-MPASVALHYAVLPLR--LEN----DELIVGSEDGIDpVSLAALT 598 Shigella flexneri...
CGS-ASRI:complete_CGSHiGG_04305  17 -------GEVFT--------ISPDLWERNQQ------QQSLLLRYFALPLK--EEN----NRLWLGVDSLSN-LSACETI 68 
EDM28112                         49 -------SGLEH--------ILEETVSSLEKMKN--VSHEYLDAALCLPLA--QDD----YTIDLAFCSL---FQLDEKC 102
jgi:M446_1171                    85 -------TGLPI--------LREEDLPAEPVLPEL-ITAEYCARARVLPLA--ADA----ETLAVGLVDALD-PEIPAAL 141
EDL57406                         53 -------LGMKY--------FELKDYQVDKVLLAQ-FPATPIFRNALLPLQ--RNN----GRVLVASADPFD-FEAIDEL 109
WP_011831773                     55 ilvrdrfLSRPAalefvqglANAEIDAADEI-----LTDEICDRYAVRPLQ--VVG----GVLHLAAVKPLL-PAQLDVI 122 Methylibium petroleiphilum...

Q55799                          142 QRQLAPhRLTlrRRGVTKDDFDNLIDQLYHDPEVQ 176 Synechocystis sp. PCC 6803
Q988B0                           77 AFHYER-TLA--LRILPRRMIAECIDRIEQSALAA 108 Mesorhizobium loti
WP_012173965                    156 ARVVHR-RVV--PVVSTKSDIIRTINEFFGFKKSI 187 Desulfosudis oleivorans
Q08WC8                          117 AFVt---GLTivPVLALAEDIERTLRRHGVLEGRH 148 Stigmatella aurantiaca DW4/3-1
Q83M21                          599 RKV----GRKvrYVIVLRGQIVTGLRHWYARRRGH 629 Shigella flexneri
CGS-ASRI:complete_CGSHiGG_04305  69 AFIt---GKPvePILLESSQLKELLQQLTPRQMQV 100
EDM28112                        103 KQWQVLyNKEiqPKLMRKSFISRKINELYHQSDEL 137
jgi:M446_1171                   142 AHLt---DRRvaPRLVGPSAFERLHRAVYGDAGEA 173
EDL57406                        110 SSLSGL-DLE--PVLALHDDVMELIKENLGVGGDT 141
WP_011831773                    123 RATAKVrLNDikVVPVARLDHQAHRRRVAATGVTL 157 Methylibium petroleiphilum
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