Conserved Protein Domain Family
SRP40_C

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pfam05022: SRP40_C 
SRP40, C-terminal domain
This presumed domain is found at the C-terminus of the S. cerevisiae SRP40 protein and its homologs. SRP40/nopp40 is a chaperone involved in nucleocytoplasmic transport. SRP40 is also a suppressor of mutant AC40 subunit of RNA polymerase I and III.
Statistics
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PSSM-Id: 398615
Aligned: 87 rows
Threshold Bit Score: 55.9906
Threshold Setting Gi: 341889187
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:THAPS_23336  531 PFKRVDDQYWGDvaTKdggAMADNSYEgafG----SDGFGVKASEKLLTVRGKDFCREKNKRKRtfngfSKSAGG--AIT 604  Thalassios...
Q581A7          1134 PFQRIDPTKVAFasN----DLRDNGPK--------AEHMALRQNQEMMRVKGKSFNKLKQKNKA-----KLYASG---VD 1193 Trypanosom...
Q4CQQ1           367 RFQRIDPTKVVFvkD----ELRDNRPG--------GEHMAFRQNQEMMRVKGKNFNKLKQKNKA-----KFYAAG---VD 426  Trypanosom...
CAM37212         180 RFQRIDPTKVTFhaD----ALRDNRPG--------EEHLVLRQNQEMMRTKGKGFNKLKQKNKG-----KFYGAG---VD 239  Leishmania...
XP_004198018     284 HFSRINPEEISFagD----ELADNSYKgaaG------NWGEAANSRLMQVRGKDFTKNKNKMKK-----GSYKGG--KIT 346  Pichia far...
XP_002498615     543 HFSRIEREKVNFeaW----ELTDNTYRgaaG------TWGEQANEKLSRVRGKDFTKNKNKLKK-----GSYRGG--SIT 605  Zygosaccha...
XP_002546019     265 HFSRIDRSKISFedS----TLQDNTYKgaaG------TWGEMANEKLMQVRGKDFTKNKNKMKR-----GSYRGG--SIT 327  Candida tr...
Q22B41           178 MFKYLKP------------EQQDFSHEsklRfgvaGDAFGDIGNEKLKETKGKGFRKAKDKLKN-----KNFCGGdgQIN 240  Tetrahymen...
Q9P785           381 PFTRVGDPSQWDfaSP---ALRDNSFNf-------EDDYGTLANRDLIVTRGKGFRQEKNKKKR-----GSYRGG--RIN 443  Schizosacc...
EPY53104         283 PFSRVGDPSQWQfaSD---AHKNNSFNf------gEDDYGAKANQDLSVTRGKGFRQEKNKKKR-----GSYRGG--RIN 346  Schizosacc...
jgi:THAPS_23336  605 MnS-FSTKY 612  Thalassiosira pseudonana CCMP1335
Q581A7          1194 V-SvRSFQF 1201 Trypanosoma brucei
Q4CQQ1           427 T-SvRSFQF 434  Trypanosoma cruzi
CAM37212         240 F-SvRAYQF 247  Leishmania braziliensis MHOM/BR/75/M2904
XP_004198018     347 LgT-GSFKF 354  Pichia farinosa CBS 7064
XP_002498615     606 LsS-GSYKF 613  Zygosaccharomyces rouxii
XP_002546019     328 LaS-GSYKF 335  Candida tropicalis MYA-3404
Q22B41           241 VnQiNSIpi 249  Tetrahymena thermophila SB210
Q9P785           444 TeV-RSFKF 451  Schizosaccharomyces pombe 972h-
EPY53104         347 LeV-RSIKF 354  Schizosaccharomyces cryophilus OY26
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