Conserved Protein Domain Family
HPP

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pfam04982: HPP 
HPP family
These proteins are integral membrane proteins with four transmembrane spanning helices. The most conserved region of the alignment is a motif HPP. The function of these proteins is uncertain but they may be transporters.
Statistics
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PSSM-Id: 398580
Aligned: 329 rows
Threshold Bit Score: 30.1741
Threshold Setting Gi: 218756225
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EHA57794         86 IVASFGAAAVLEFYSIEAPLAQPRNAILGQVISALVGTI---V-ATIFGGperllqstsddptlgfrslvYRWA--GGAL 159 Pyricularia ...
jgi:Desmer_3479  61 LFPPLAATCFINSSCVYLRVARPKPVIVGHFVSAMGGLAgvwTgELLAGGtdl---------------viPL----KLSL 121 Desulfosporo...
WP_012805384     55 LYPPLAATCFIGATCTYLRVARPKSVIVGHFISAVGGLLgvaAgEAMFGGtsl---------------aiPA----KLGL 115 Desulfomicro...
jgi:Dret_0894    55 LFPPLAATCFIGATCVYLRVARPKAVIVGHCVATIGGLVgcyLgTLMLGEarf---------------vaSV----KLGL 115 Desulfohalob...
WP_014261444     55 LYPPLAATCFINATCAYLRVARPKSVIVGHFIATVGGLLgvhAgEWALGGtsl---------------avPA----KLGL 115 Desulfocurvi...
jgi:Acry_0680    52 LIPPFAATMTIVLCLPDAAVAQPFAVIAGSTLGTLIGTA---------AAa------------------gLGPGpqTAAL 104 Acidiphilium...
jgi:Sulac_3425   46 LVPPFAATLSILYYLPQQPVAQPAPVVFGSTLGATIGTL-----FHLVGVh------------------gPA----WAAL 98  Sulfobacillu...
Q0VKT9           62 IFPSLGASAFLLFHLPLAEAASPRNVLCGHLIGALCGWA---S-LWVCGLhdapaafi-----tgvewprVV----AAGL 128 Alcanivorax ...
WP_012237270     88 VFPSLGPTAFLFFYTPTAASAAPRTTIVGHSIGIAVAYM---S-LLITGLthagpata-----tgvtlprAI----AAAL 154 Sorangium ce...
Q1ASI0           44 LFPSLGPTAFLFFETPLAEISTPRNTMIGHLVAAGSGYA---S-LAAFGLldapgvlq-----agvgparIG----AAAL 110 Rubrobacter ...
EHA57794        160 ACAAATACMALTGTVHPPAGATALMAVVDDRIvelGWWYIPI-------MLLGCALMLGVALLVNN-VQ-RRFP 224 Pyricularia oryzae...
jgi:Desmer_3479 122 ALLCAALLMQVFDADHPPAAATAVIPAILPLP--------MPaqlfpayMAWGATIAVLFALVWNRvWfefpak 187 Desulfosporosinus ...
WP_012805384    116 AVFFSAVFMQILDADHPPAAATAAIPAILPLP--------VPiamlplhMAWGAVLAVVFTVVWNRvwfecpap 181 Desulfomicrobium b...
jgi:Dret_0894   116 AVLLASAFMQVLDADHPPAAATAAIPAILPLP--------ASglvlplhMAWGGVLAVVFAVAWNRvwfecpvp 181 Desulfohalobium re...
WP_014261444    116 AVLLASALMQILDADHPPAAATAAIPAILPLP--------APdlllplhMAWGGVLAVVFSVAWNRiwfecpap 181 Desulfocurvibacter...
jgi:Acry_0680   105 AAVAALAVLPRLRAYHPPGVALALYPALLHP----GPWFAAAv------VLPFTLAVVASASLLSRwV--ASWP 166 Acidiphilium crypt...
jgi:Sulac_3425   99 AAIVLFWLLPRIGLYHPPGIALSMFPLLLHP----GLWFPVTv------VLPFTLIAVSSHWVLSRrwpgwpky 162 Sulfobacillus acid...
Q0VKT9          129 SLGMASALMILFRVAHPPAAATALIVSLGL----------MHelqqlpvLLSAVALLVAQAFVINR-LAgIPYP 191 Alcanivorax borkum...
WP_012237270    155 SLGLTAGLMVLARAPHPPAGATTLIVSLGI----------LSrppmllvLLGGVVLLTLQAILINR-LAgVDYP 217 Sorangium cellulosum
Q1ASI0          111 SVALTSALLLLLRSPHPPAGATTLIVSLGL----------LStphelgmLALGAALLTAVGWAINR-AAgvpvp 173 Rubrobacter xylano...
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