2QJV,1X8M


Conserved Protein Domain Family
KduI

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pfam04962: KduI 
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KduI/IolB family
This family includes the 5-keto 4-deoxyuronate isomerase enzyme EC:5.3.1.17 that is involved in pectin degradation. This family aldo includes bacterial Myo-inositol catabolism (IolB) proteins. The Bacillus subtilis inositol operon (iolABCDEFGHIJ) is involved in myo-inositol catabolism. Glucose repression of the iol operon induced by inositol is exerted through catabolite repression mediated by CcpA and the iol induction system mediated by IolR. The exact function of IolB is unknown. Members of this family possess a Cupin like structure.
Statistics
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PSSM-Id: 398565
Aligned: 69 rows
Threshold Bit Score: 166.636
Threshold Setting Gi: 33301324
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2QJV_A         5 LLSTC--TSESGn---IQHISPQNA--GWEYVGFDVWQLXAGESITLP-----SDERERCLVLV---AGLASVXAadSFF 69  Salmonella ente...
Q9A873        26 YLMQG--LFQDGqivlTYNHAERFV--VGGVVATSPIKLPDQTEPASAaghpfLERRELGVINVgdtTGKITVDG---VA 98  Caulobacter vib...
1X8M_A        26 FLVEK--VFVADeytmVYSHIDRII--VGGIMPITKTVSVGGEVGKQLgvsyfLERRELGVINIg-gAGTITVDG---QC 97  Escherichia coli
P50843        24 FLMDS--LFTENkltmYYSHEDRVVi-GGAAPGQSELKLDAGDFLKTDf---fLERREIGIINVg-qPGAVRVGD---DE 93  Bacillus subtil...
Q16DJ5         2 HIAPF-----DNqnkpIVDAGDSLV----PLNYFNIVKLKKGESFGYA-----VPGYETCIAPA---TGLLDVATggfEA 64  Roseobacter den...
Q09EA1        11 LITRH----RRGfprgLTWVTREGEaeLDTGLDFGLHRMGRGESFSHR-----TA-KETAWVLL---SGQAEVEL--EGA 75  Stigmatella aur...
SFZ41635     365 LLIKNpcGFADGlnsiVTMQDSPTA------MSFSSLKLNKGQSHQFN-----SS-YEFAALLM---TGKVVFQY--GSY 427 Legionella pneu...
LANL:BG06_42   4 KLGEL----NEGyn-vLTEMNGQCS---DMLMDIGIYKMTNGKEELLF-----DNKNETAVLLL---EGAIRLEW--EGM 65  Bacillus thurin...
Q898E9         4 KLKEL----EKGhn-iLVESNGKHS---EMMMDISICKLEIGQEEFFI-----EKNKESSFLLL---LGKVLIKW--EDK 65  Clostridium tetani
WP_012060705   4 NLDRL----ENGen-iLCQINGKNK---EMLMDVTVEKLEKNQRREYL-----KSDKEIAVLLL---TGQVKINW--LEN 65  Clostridium bei...
2QJV_A        70 YRIGQR-XSPFErIPAYSVYLPHHTEAXVTA-Et---dLELAVCSAPGFGELPVR-LISPQEVGVEHRGXGRNQ----RL 139 Salmonella ente...
Q9A873        99 YEIVPR----------DGLYVTMGAKDVTFEgVdg--aARFYLVSLPAHAAFETK-KLAFADAIPLERGALETSn--eRT 163 Caulobacter vib...
1X8M_A        98 YEIGHR----------DALYVGKGAKEVVFAsIdtgtpAKFYYNCAPAHTTYPTK-KVTPDEVSPVTLGDNLTSn--rRT 164 Escherichia coli
P50843        94 YVLQTK----------DFLYIGMGNQDVSFSsLng-ekAKFYFVSACAHKSYPTQ-KAALSELTPDRLGDDAASn--vRS 159 Bacillus subtil...
Q16DJ5        65 KNLGGRgVDVWD-GEPEGVYVPSGQEARFTClSd---sAEVFVAGAKFDEVLEPF-AVRADEIDLVQYGSDDTKt--hRK 137 Roseobacter den...
Q09EA1        76 RASLAR-ASLFD-EAPTVVHVPVGAQVRIEAtSe---eVEWAVVSATNPNAFAPR-IFFPRDIQDELRGKGLVQdaavRT 149 Stigmatella aur...
SFZ41635     428 SQEVER-TDYFS-QSPYVLHCSKNEVSSVIA-Lt---dCEILLMETENENLFSPIlFDASNMLELDNRGEGVLEntsyRL 501 Legionella pneu...
LANL:BG06_42  66 EQVIQR-QSVFE-ENPWCLHVSKNVKVTITA-Ls---dSEVLVQKTDNDQEFASK-LYTPNECQSVVAGDGVWEgtaqRV 138 Bacillus thurin...
Q898E9        66 EQEIER-NSLFD-EDPWCLHVPKGVNVKITA-Lt---dAEVLVQKTENSRVFSCK-LYSPKECRSDVFGNGVWNdtarRI 138 Clostridium tetani
WP_012060705  66 SKSIER-KSVFD-DDPWCLHVPKNVGVTVEA-Se---dSEILIQSTENLGFFEPK-LYSPSECKSEIFGEGTWNgtarRV 138 Clostridium bei...
2QJV_A       140 VHNILPDSQL--ADSLLVVEVY-TNAGATSSWPAHXHDTAVEG----QETYLEETYYHRFNPPQGFCLQRVYTdDRSLDE 212 Salmonella ente...
Q9A873       164 IYQYIVPTTCk-SAQLLLGMTVlKPGSVWNTMPPHLHDRRSEAyfyfGLGENDRVFHYMGEPDE--------------MR 228 Caulobacter vib...
1X8M_A       165 INKYFVPDVLe-TCQLSMGLTElAPGNLWNTMPCHTHERRMEVyfyfNMDDDACVFHMMGQPQE--------------TR 229 Escherichia coli
P50843       160 LYKVIHQDGIk-SCQLMMGITMlDQNNNWNTMPAHVHDRRMEAylylDLEKDSKVFHFMGQPDE--------------TR 224 Bacillus subtil...
Q16DJ5       138 IKHILGANQHerVGRLLVSELFtVGAGGWSGFPSHKHDTDRLP----DETRHDETYNFRFKPNYGSGLQMLQReDNEPGD 213 Roseobacter den...
Q09EA1       150 VRLAFDTTHRp-EGAFVVGEVI-NSPGRWSSYPPHHHAQ-------------TELYHYRFTLPQGYGH------AELGDD 208 Stigmatella aur...
SFZ41635     502 VRTVFDKRNRp-ESNLVVGEII-TFQGRWSSYPSHYHQQ-------------PEIYHYRFSEPQGYAF------GENGKE 560 Legionella pneu...
LANL:BG06_42 139 IRTIFDYNNAa-YSNMVVGEVI-SYPGRWSSYPPHHHDQ-------------PEVYYYRFNKPQGFGC------AMVGED 197 Bacillus thurin...
Q898E9       139 VRTVFDYSNAp-YSNMVMGEVI-TYPGKWSSYIPHHHPQ-------------PEVYYYRFNKPQGFGC------AFIGEE 197 Clostridium tetani
WP_012060705 139 VRTIFDYKNAp-YSNMVIGEVI-TYPGKWSSYPPHYHPQ-------------PEVYFYKFDKPRGFGL------CLNGDK 197 Clostridium bei...
2QJV_A       213 CXAVYNRDVVXVPXGYH-PVATIAGYDNY-YLNVXAGPL--RXWRFTWEENHAWI 263 Salmonella enterica subsp. enterica sero...
Q9A873       229 HIVIANEEAVMSPPW---SIHMGSGTANYtFIWAMGGEN-----LDYTDMNVLDI 275 Caulobacter vibrioides CB15
1X8M_A       230 HIVMHNEQAVISPSW---SIHSGVGTKAYtFIWGMVGEN-----QVFDDMDHVAV 276 Escherichia coli
P50843       225 HLVVGNEQAVLSPAW---SIHSGAGTSNYsFVWAMAGEN-----YTFTDMDLIPM 271 Bacillus subtilis subsp. subtilis str. 168
Q16DJ5       214 AYHIVDGSTICIDKGYH-PCCVLPGYEMY-YFTILGGLSq-RSLKQYFQPTHAEQ 265 Roseobacter denitrificans OCh 114
Q09EA1       209 VYKVKQYDTVKILGGVDhPQVSAPGYGMY-YLWVVRHQPgnPYRGFEFTEEHRWV 262 Stigmatella aurantiaca DW4/3-1
SFZ41635     561 VMRIEHYDTYQIANNQEhAHCAAPGYALY-TLWFIRHLNnnAYTLPTFIKDHEWT 614 Legionella pneumophila
LANL:BG06_42 198 AYRVVHNSFITIPGELDhPQATAPGYAMY-FCWMIRHFEnnPWNDRIMEEEHKWL 251 Bacillus thuringiensis
Q898E9       198 AYKITDNSIATIPGGLVhPQTSAPGYAMY-YCWMIRHLEnnPWTDRINEKEHEWL 251 Clostridium tetani
WP_012060705 198 AYKILDNSFATIIGGDVhPQTSAPGYAMY-YCWMIRHLEnnPWRDRIDVDEHKWL 251 Clostridium beijerinckii
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