Conserved Protein Domain Family
GFA

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pfam04828: GFA 
Glutathione-dependent formaldehyde-activating enzyme
The GFA enzyme catalyzes the first step in the detoxification of formaldehyde. This domain has a beta-tent fold.
Statistics
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PSSM-Id: 398481
Aligned: 38 rows
Threshold Bit Score: 66.9977
Threshold Setting Gi: 500090327
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5ATD8         54 FVCHCTDCRKITASMFATNFTISDKYLTHERGq-nRLTSYSQSktIATGKTMTN-YFCSTCGSLMYRR--SSRFPGLSIL 129 Aspergillus ni...
XP_001275138   23 AVCHCLTCRKYS-SGSTVNLLVPKDHFSITSG---TPKEWHIV--HQTGMHMTT-RFCGDCGCLLYKTadRAEFQDGVVV 95  Aspergillus cl...
Q2GBB1          3 YACHCHGCQRRQGTSFALNQQVLLAGF-VAEGe-vLVSEVEG----HGGARVAH-HACPRCLTRVWTV--NDQRPEVATI 73  Novosphingobiu...
Q21X16         30 HCCHCRWCQRESGASFALNAMIEADRVQLLQG---AVEVVNTPslSGKGQKISR---CPQCRIAVWSNy-AGAGDAVRFV 102 Rhodoferax fer...
Q121E1         31 YACHCTDCQRRSGAAMRLAMWVERSALTVKQGs-pELRTFSF-----GEGRHRRaKICVDCDTRLWAE--PEDKPELAIL 102 Polaromonas sp...
Q30W13         26 YLCHCERCRKDSGSAHAANLFSSTAELRWLEGe-eHVRTFD-------LDGHIK-SFCSRCGSALP-N--IQMGGTLLVV 93  Desulfovibrio ...
Q47YQ7         26 YQCHCKQCQQLSGSAFTSNILTAPTNIEWLKGk-rNVTVYDH-----PTRGFSK-SFCSLCGSALPF---INKNKTTLII 95  Colwellia psyc...
jgi:Oant_3020  43 LNCHCSLCRRATGSAFKAFGGIKTHALEETNSkssLMLV---------GNEIDHdVRCASCASFLYS---IVRGGEYVHV 110 Ochrobactrum a...
WP_011766340   27 YRCNCSICRRTRF----WPAVVKPDAFRLLAGa-gELVQYRF------NTGKNHhYFCRHCGVRPYgignETPMGKVYGV 95  Azoarcus
Q2KBD7         28 HVCTCTRCQRASGSALAHNVWFREDDVRIVSG---DYSVWFPQ--GETTPDVMK-AFCRICGGGGFSKs-GTYFPGTVVI 100 Rhizobium etli...
Q5ATD8        130 RTGTVDDFsl---heGRLKPR-VEQ-FVKD 154 Aspergillus nidulans
XP_001275138   96 LAGTLDDPrg----lDAAKPD-AEF-FIGD 119 Aspergillus clavatus NRRL 1
Q2GBB1         74 RTGTRDDS-------PDLVPA-FHI-WTSR 94  Novosphingobium aromaticivorans DSM 12444
Q21X16        103 RVGTLDEP-------DRLPPD-IHI-FTAS 123 Rhodoferax ferrireducens T118
Q121E1        103 LPGTLHNH-------REFEPV-AHL-WTRS 123 Polaromonas sp. JS666
Q30W13         94 PAGSLDCD-------VPIRPD-GHI-FYAD 114 Desulfovibrio alaskensis G20
Q47YQ7         96 PAGSLNEL-------PDLKPQ-ANM-FTSE 116 Colwellia psychrerythraea 34H
jgi:Oant_3020 111 NYGVLAEE-------PKLKPS-AHI-FVGS 131 Ochrobactrum anthropi ATCC 49188
WP_011766340   96 NLGCLDDVteeelaaAPITYVdGLHdRWQD 125 Azoarcus
Q2KBD7        101 AAGTFADP-------SFPAPD--HVhWWGD 121 Rhizobium etli CFN 42
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