Conserved Protein Domain Family
Cyclase_polyket

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pfam04673: Cyclase_polyket 
Polyketide synthesis cyclase
This family represents a number of cyclases involved in polyketide synthesis in a number of actinobacterial species.
Statistics
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PSSM-Id: 428058
Aligned: 38 rows
Threshold Bit Score: 120.012
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Cfla_3338    3 HRLLIVARMDPGAWSDVAGLFAESDASDLPHDLGVVRRDLYAYQGLYFHHVEFAGS-PDAAMARARD--RADFRRLSADL 79 
CCH32744         2 FSTLIVARMDPGSSPDVAELFAHFDTTEMPHLMGTRRRQLFSYRGLYFHLQDFETEhGHESIEAVRT--EPRFVRISDEL 79 
jgi:Caci_3545    2 HSTLIVARMDPGSAGDVAKLFGEFDSTDMPGRMGTRRRELFTYRGLYFHLQDFDHEhGGEDIEAAKT--DPQFVRISADL 79 
WP_011906074     2 YSTLIVGRMQPQWSTEVAELFGAFDDTEMPHRMGTRRRELFHYQGLYFHLQDFDGEyGGDRIAQART--DPRFIRISADL 79  Salinispora t...
jgi:SACTE_6345   2 HSSLIVARMDGASQHEVARLFGEFDRTEMPHLMGTRRRQLFAYRGLYFHLQDFDTDdGGRLIEEART--DPRFVRISDDL 79 
Q9XCV6           2 HSTLIVARMEPGSSTDVAKLFAEFDASEMPHLMGTRRRQLFSYRGLYFHLQDFDADnGGELIERAKT--DPRFVGISEDL 79  Streptomyces ...
BAC70095       119 YSAVIVNTQRQEHIPEAARLFAESDATDIPQKMGTLRRQIYLWRGIYLHIQDFAVAnSMEAISEVWTegDPRFLQLVDDL 198
WP_013873656     2 QRTLIVAKVAPGTEAEVARIFAASDRTGLPQVAGVSHRSLYSLGDLYVHLLETEHE-SSRVLADISG--QEEFGRVTAEL 78  Frankia
WP_013734504     2 DRTLIVAKVVPTAENAVAEIFAESDTTELPHLVGVAHRSLYRLHDLYVHLLETDTP-GDGAVEAARD--HPEFRRISARL 78  Micromonospora
WP_012013733     2 ERSLIVAKVDPSAEERIAEIFAESDATELPRLAGVQHRSLYRLQDLYLHLLETELP-GENAVAEARC--HPEFIRVSERL 78  Salinispora t...
jgi:Cfla_3338   80 EPYVRPYDPAtWRSPADATATPFYRWT 106
CCH32744        80 KPFIEAYDPRtWRSPADAMASRFYHWE 106
jgi:Caci_3545   80 KPFIEAYDPAtWKSPADAMASRFYRWS 106
WP_011906074    80 KPFIRPYDPAtWRSPTDALATRFYHWA 106 Salinispora tropica
jgi:SACTE_6345  80 KPFVEAYDPAtWRSPADALAQRFYAWg 106
Q9XCV6          80 KPFIEAYDPAtWRSPADAMATRFYNWE 106 Streptomyces venezuelae
BAC70095       199 TEIIPPYDPQ-----GNSLATRFYHWA 220
WP_013873656    79 AHFIQPYLPT-WRSSRDAVARCFYTYE 104 Frankia
WP_013734504    79 RPYITPYLPD-WRSPRDAMARCFYRFD 104 Micromonospora
WP_012013733    79 RPYVSPYLPT-WREPRDAMARCVYRFD 104 Salinispora tropica
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