Conserved Protein Domain Family
Keratin_matx

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pfam04579: Keratin_matx 
Keratin, high-sulphur matrix protein
Family of Keratin, high-sulfur matrix proteins. The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins. The matrix proteins include the high-sulphur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas microfibrils contain the larger, low-sulphur keratins (40-56 kDa).
Statistics
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PSSM-Id: 398332
Aligned: 11 rows
Threshold Bit Score: 76.3682
Threshold Setting Gi: 1621898793
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9BYR8         3 CC---ALRSCSVPTGPATTFCSFDKSCRCGVCLPSTCPHEISLLQPICCDTC-PPPC----CKPDTYVPTCWLLNNCHPT 74  human
AAS00526       3 CCesrLQGCYSVPTGPPTTICSSDVRCQCGACLPSTCPHEIRLLQPTCCDTChPPCCvpdsCVPDSYVPTCWLLNSCHPT 82  goat
EHB02859      39 sC---LQGGYTARTGPATSLCSSDICCPCGVCLPSTCPHKISLLQPTRCDAC-PPPC----CVPDSYVPSYWLLSKCDPA 110 naked mole-rat
P02446         3 CC---APRCCSVRTGPATTICSSDKFCRCGVCLPSTCPHNISLLQPTCCDNS-PVPC----VYPDTYVPTCFLLNSSHPT 74  sheep
XP_004859473   3 CC---VPRGCSVPSGPATTICSSDKSCHCGVCLPSTCPHEISLLGPTCCDPC-PPPC----CQPEVYVPTCWLLSTSHPT 74  naked mole-rat
XP_005321891   3 CC---IARCCSVPTGPATTICSSDKSCRCGVCLPSTCPHQLHLLGPVCCDNC-PPPC----CQPDTYVPTCWLLNSSHQT 74  thirteen-lined ...
XP_003768292   7 CL---HDCCCSVPTGPATTICSSDKCCRCGVCLPSTCPHEISLLQPICCDCC-PPPC----CMPDPYVASCWLLNSGHPR 78  Tasmanian devil
Q9D638         3 CC---VARCCSVPTGPATTICSSDKSCRCGVCLPSTCPHTIWQLEPTCCDNC-PPPC----HIPQPCVPTCFLLNSCHPT 74  house mouse
XP_001520588   6 CC----RTCCSVPTGPATTICSSDKCCRCGVCLPSTCPHTTWLLEPTCCDNT-PPPC----HVPQPCVPTCFLLNSCLPT 76  platypus
XP_004012927   3 CC---ARLCCSVPTSPATTICSSDKFCRCGVCLPSTCPHTVWLLEPTCCDNR-PPPY----HVPQPSVPTCFLLNSSQPT 74  sheep
XP_028610784   3 gcnsylqGCHSVPTGPATTLCSSEIYCPCGVCLPSTCPHKISLLQPSCCNTC-PPPC----CVPDSYVSSCWLLNKGYPA 77  Grammomys surda...
Q9BYR8        75 PGLSGINLTTYVQPgCE 91  human
AAS00526      83 PNLSGISVTTCVQP-CE 98  goat
EHB02859     111 PNLTKVSVTTCIHA-CD 126 naked mole-rat
P02446        75 PGLSGINLTTFIQPgCE 91  sheep
XP_004859473  75 PGLSGINLTTFVQPgCQ 91  naked mole-rat
XP_005321891  75 PGLSGINLMTHVQCgCE 91  thirteen-lined ground squirrel
XP_003768292  79 PGLYGINLTTYTQPgCE 95  Tasmanian devil
Q9D638        75 PDLLTVNLTTYVQPgCE 91  house mouse
XP_001520588  77 PGVESIPLTTCIQPcPC 93  platypus
XP_004012927  75 PGLESINLTTYTQSsCe 91  sheep
XP_028610784  78 PNLKGVSVSTCVEP-CE 93  Grammomys surdaster
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