6PPB


Conserved Protein Domain Family
Herpes_UL17

?
pfam04559: Herpes_UL17 
Herpesvirus UL17 protein
UL17 protein is required for DNA cleavage and packaging in herpes viruses. It has been shown to associate with immature B-type capsids, and is required for the the localization of capsids and capsid proteins to the intranuclear sites where viral DNA is cleaved and packaged. In the virion, UL17 is a component of the tegument, which is a protein layer surrounding the viral capsid.
Statistics
?
PSSM-Id: 398316
Aligned: 37 rows
Threshold Bit Score: 246.569
Threshold Setting Gi: 81966529
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6PPB_KK    1 MDAHAINERYV------GPRCHRLAHVVLPRTFLLHHAIPLEPEIIFSTYTRFSRSPGSSR------------------- 55 
Q18LD4     1 MEIHLFNEIGK------VTDGPFMVHVALSTYRFDLGQIDM---LFIRSVFLHNKHISC--------------------- 50  Elephantid herpesvi...
Q9QJ20     1 METHLYYDTLYq-----YQGGVYPAHICLPTDAYLPMRVDCIESLYFRCVFFKNGMHYTE-------------------- 55  Human herpesvirus 6...
AUI40782   1 METHLFSDLAFeq--vfEEDPQLPLHVVLDPVDLSFAEAETVRYVYYRSDPDPVGR------------------------ 54  Rhesus cytomegalovirus
P16799     1 METHLYSDLAFea--rfADDEQLPLHLVLDQEVLSNEEAETLRYVYYRNVDSAGRSTGRAPggdeddapasddaedavgg 78  Human herpesvirus 5...
Q8QS07     1 METHLYSDLAFea--rfAADWQLPLHLVLDHSALSCEEAETLRYVYYRNAVRPAPPPQSTEqggpeq------------- 65  Chimpanzee cytomega...
Q997C6     1 METHLCSELNRda---tGDRERLPVHLFLTERTLPYAVFRGLRALHVRVAGAADAE------------------------ 53  Tupaiid betaherpesv...
CAJ86575   1 METHLRFEQAAse---dDRDRLVPVHVVFAEDALSYREFEGLHTLCFKIISRPDAR------------------------ 53  Murine cytomegalovi...
Q9DWA9     1 METHLRFEPDDgdrgspAAARLVPVHVVFNQDTLSYGDFRALSSVTYRVVSPEGAGP----------------------- 57  Rat cytomegalovirus...
Q9WI09     1 MDVHINNWRFL------SHRCDLLVHVVLPTQLLEKFNIGMFDNVVFYVKTRFHDGKMPTP------------------- 55  Bovine gammaherpesv...
6PPB_KK   56 ----------RLVV-CGKRV-LPGEENQLAsSP------------------------SGLALSLPLFShd---gNFHPFD 96 
Q18LD4    51 ----------WIRIpFNIRN-VDVDLHRYFsfkpkrkn-----------ertiilarPVVFFSLPLLSpgidnnKLAVEA 108 Elephantid herpesvi...
Q9QJ20    56 ----------WSKLkFTVIS-REIKFKDVLkNAdfde-----------------lftGLVVMTIPIPIvdfhfdI----D 103 Human herpesvirus 6...
AUI40782  55 ----------WRRAtFRVFL-RPFELLTYLrDAgltvapt-----------frvvchHALFTTLGIRCae---qrLSGAQ 109 Rhesus cytomegalovirus
P16799    79 drafdrerrtWQRAcFRVLP-RPLELLDYLrQSgltvtlek---------eqrvrmfYAVFTTLGLRCpd---nrLSGAQ 145 Human herpesvirus 5...
Q8QS07    66 -----daaedWQRAaFRVLP-RPLELLAYLrDSgltvtlpa--------ddpgvrmyYAVFTTLGLRCpd---krISGSQ 128 Chimpanzee cytomega...
Q997C6    54 ----------WRRLaYQTWP-RELLLARLVpnrlrgd--------------ervraaYGLATTVWLDCpg---rvVVPTR 105 Tupaiid betaherpesv...
CAJ86575  54 ----------WEHIpYFERLdREFVLKSLFhDKcrhlsaspgdgpwtlhgggdencrYGLAFSVVLHLrd---veWWK-D 119 Murine cytomegalovi...
Q9DWA9    58 ----------WRRVpYVQRVdRDFSVGSLFrRErarlsadpgpgvpafygderercnFGLVFTALVRVre---gaWWH-D 123 Rat cytomegalovirus...
Q9WI09    56 ----------YLKV-WGLFF-NHSYDFPNIdS--------------------------GLALSLPIFVer---dmYNPLN 94  Bovine gammaherpesv...
6PPB_KK   97 ISVLRISC---------------------PGS------NlSLTVRFLYLSLVVAM------------------------G 125
Q18LD4   109 MCICRFVN---------------------TNGa-----E-FFDLEFMYEDILRE-------------------------- 135 Elephantid herpesvi...
Q9QJ20   104 SVILKLVY---------------------PQL------V-HREIVLRLYDLIC--------------------------- 128 Human herpesvirus 6...
AUI40782 110 MLYLRLVW---------------------NEE------R-FRDWEFLVRDLLREEmsvcqstep---------------- 145 Rhesus cytomegalovirus
P16799   146 TLHLRLVW---------------------PDG------S-YRDWEFLARDLLREEmeankrdrqhqlatttnhrrrgglR 197 Human herpesvirus 5...
Q8QS07   129 MLYLRLMW---------------------DQG------R-QRDWEFLARDLLREEieanridrhqrelaearavnnrrlT 180 Chimpanzee cytomega...
Q997C6   106 LVRLRFAYrsardsptvrgageappapavADRdrdpvdR-SFVLDFWVKDLLAARepmypasddgdevdrpaaaghggaT 184 Tupaiid betaherpesv...
CAJ86575 120 VIKFRLFI---------------------GDD------E-TVDIDCTFVRLLREGlrffgevrrtrqprsgprsassrlL 171 Murine cytomegalovi...
Q9DWA9   124 LLRIRLLV---------------------RDE------E-VVEIDCTLARLLWEGfrffervrrnrpaavggrpggrggG 175 Rat cytomegalovirus...
Q9WI09    95 MVWLKVYY---------------------PVSk-----Q-TKFLSFFYMQLVQGQregal-------------------- 127 Bovine gammaherpesv...
6PPB_KK  126 AGRNNAR--------------------------------SPTVDGVSPPEGAVA--HPLEELQRLARATPDPAPTRgpLQ 171
Q18LD4   136 ---------------------------------------FPDVGDECIKEDDHV--DDFFTLGAC-------------SS 161 Elephantid herpesvi...
Q9QJ20   129 ---------------------------------------IRPSSDRPSEVSAKNigIDFYQLTSQ-------------GN 156 Human herpesvirus 6...
AUI40782 146 ------------------------------adrpdpsllMTDAMLELAKSSSTT--APFFEMPSSGTGNNNASSAS--AA 191 Rhesus cytomegalovirus
P16799   198 NNLDNGSd------------------------------rRLPEAAVASLETAVS--TPFFEIPNGAGTSSAN------GD 239 Human herpesvirus 5...
Q8QS07   181 SGTARPLlssattssapshpllgsepafgrsdspamaaaAAAAAELPPLESAAG--TPFFQIPRAPAGADGGSG----QS 254 Chimpanzee cytomega...
Q997C6   185 ATT------------------------------------APDAVTAAAAAAAVAdgGGLARFFHIDG-----------DR 217 Tupaiid betaherpesv...
CAJ86575 172 HHHPHHHragaagd------------------ddgdvddDEGLPEGLLGAAADG--PGFFDLGD--------------NR 217 Murine cytomegalovi...
Q9DWA9   176 AAIAAEAeaea-------------------------grdEEELPEDVAAQCGLD----FFELDD--------------RR 212 Rat cytomegalovirus...
Q9WI09   128 ----------------------------------rvqkkDNSTKNILPPISSCPftQIYNSILESHTGIITAKNT---VD 170 Bovine gammaherpesv...
6PPB_KK  172 VLTGLLR----------AGSDGDRATHHMALEAPGTVRGESLDPPVSQKGPARTRHRPPPVRLSFNPVNADV-----PAT 236
Q18LD4   162 ATVGTVQnstgqdhrspVNDNNEHTVTPGPLEPPSVVRGVD------SNSGNGLNNMTPGKCNGYPTGKHVWk----AID 231 Elephantid herpesvi...
Q9QJ20   157 KQTPDEEkr-------------cLFFQQGPLEPPSTVRGLK----AAGNAKPMQFPAHVNEKMTESFLSDSWfe--qKVR 217 Human herpesvirus 6...
AUI40782 192 DESSQVErrv----iqfLRGDSELTYHAGPLEPPSKIRGHEIV-QPRIEVNPDVIYASGPHEDDRTSKTDEWqk-ggVLR 265 Rhesus cytomegalovirus
P16799   240 GRFSNLEqrv----arlLRGDEEFIYHAGPLEPPSKIRGHELV-QLRLDVNPDLMYATDPHDRDEVARTDEWkg-agVSR 313 Human herpesvirus 5...
Q8QS07   255 GGPSDLElrv----arlLRGDPEFTYHAGPLEPPSRIRGRELV-QTRVDINPDLMYATSAQEPVEVSRTDEWkg-agVSR 328 Chimpanzee cytomega...
Q997C6   218 KLSPSLKeyl----drfAGVRDGEAAAPGPLERPSWVRGRPSTALLAARRLEFLDAGDEKAVG-SASRTARWfrvdnDLR 292 Tupaiid betaherpesv...
CAJ86575 218 KMSEEMEdrl-----arFALKRVSAADFGPLEPPSKVRGRE---IKARRGEFFRDGDAPAAPDPVRSRSDRWfgcdnAIR 289 Murine cytomegalovi...
Q9DWA9   213 RMSEDMErrl-----arFAKKRVSAVDFGPLEPPSKVRGRE---IVNPRGEFFSDGEAVEVPPPVRSRTDRWfgsdnAVC 284 Rat cytomegalovirus...
Q9WI09   171 VLHDMLEtr-----------pERQIKHHLALETPGKVRGTVK--VEPREAAPSNPCTGELVKLQVSFRETSKq----ITH 233 Bovine gammaherpesv...
6PPB_KK  237 WRDATNVYSGA-PYYVCVYE----RGGRQED------DWLPIPLSFPEEPVPPPPSLVFMDDLFINTKQCDFVDTLEAAC 305
Q18LD4   232 IYRLQPLHTPSdNVYRVLYDkssfLKPRISQpp---yDGLASCFF-----------LRHEVYRFMRVIGTEIIDKFFDVM 297 Elephantid herpesvi...
Q9QJ20   218 CKKILDFTQTY-RVVVCWYElsfsREMQIEN------NLLSASQLKrvn----aadFWDRTDRYLRDIGSRVLTHIVKTL 286 Human herpesvirus 6...
AUI40782 266 LGSVWDVRQRL-RLHVLWYAqsfwRSRGLKYed--reEDLRLTLD-----------SYFDRLSVEYQLLREVYREIKAVL 331 Rhesus cytomegalovirus
P16799   314 LREVWDVQHRV-RLRVLWYVnsfwRSRELSYdd--heVELYRALD-----------AYRARIAVEYVLIRAVRDEIYAVL 379 Human herpesvirus 5...
Q8QS07   329 RREVWDVQRRV-RFHVLWYVnsfwRTCGLTYdd--neADLYRALD-----------AYRSRIAVEYVLIRAVRDEIRLVL 394 Chimpanzee cytomega...
Q997C6   293 PVPVQDAERRR-DGYVFWYResccAPWTLTTapddaaAAAARESFEr---------GLEAWPRCLLAVCEEVAERLALAL 362 Tupaiid betaherpesv...
CAJ86575 290 ISYAQEVTGSR-RFAVIWYSesigSTVDVDVgraddgEAAVTSFE-----------HTRRWETAVTRVYGATSRQLAAAV 357 Murine cytomegalovi...
Q9DWA9   285 VSRVQGVLGPR-SFLVVWYSesagADVEGESdglddgPAVVLCFQ-----------HVRRWDLTLTRVYNAAAAGLGEAV 352 Rat cytomegalovirus...
Q9WI09   234 IARVKHIISGL-QYYVCFYDslisGDFFTFQsv---lDILPQ----KDLAAIDPLAIILSDRQFLQTKQDGFINSLELKC 305 Bovine gammaherpesv...
6PPB_KK  306 RTQ-GYTLRQRVPVAIPRDAEIADAVKSHFLEACLVLRGLASEASAWIRAATSPPLGRHACWMD---------------- 368
Q18LD4   298 NSEdG-ILFQKFLCHV-PMNALDISIPEMVYLSQNVWTSHVDPRSCIIKGVVAHLFKNPRRp------------------ 357 Elephantid herpesvi...
Q9QJ20   287 QIHnR-QFKQKFNCNF-PVNFSFEHLLSFMQLGKDFWILNLTLDSCIIKAIICFLGFRNGR------------------- 345 Human herpesvirus 6...
AUI40782 332 RSDr--MVAQKFSCHL-SIETSWLLIWELFDRALELWRDQADVNSCIIKALAHKLRSKAQSshg---------------- 392 Rhesus cytomegalovirus
P16799   380 RRDgG-ALPQRFACHV-SRNMSWRVVWELCRHALALWMDWADVRSCIIKALTPRLSRGAAA-AAqrarrqrersapkpqe 456 Human herpesvirus 5...
Q8QS07   395 QHRr--ALRQLFACHV-VRKMSWIHVWELFRHALELWIDRADERSCIIKALTPRLGRPARA--Ptperldrdasa-lkpy 468 Chimpanzee cytomega...
Q997C6   363 RSGp--ELRQTLACHL-AADGDYRALPDLLVLSRNVWLIRMDEDSCIIKALVEYVAQTDRSt------------------ 421 Tupaiid betaherpesv...
CAJ86575 358 TRVg--GLAQRFYVNL-YAGLRAGDLVELLLLSRDAWLVNGTGGGCIIKALSSDLHRRRRS------------------- 415 Murine cytomegalovi...
Q9DWA9   353 RRGg--ALAQRFRVDL-CSDLRGRDLAELLGLSRDVWLVNATGDGCIIKALSHDLRPRRRD------------------- 410 Rat cytomegalovirus...
Q9WI09   306 IKQ-GFTVHQKLPILIEKDDECVELIQDHFTEACFVIRQIINPESAWIQCAISTFHGKGGCWMD---------------- 368 Bovine gammaherpesv...
6PPB_KK  369 ------VLGLWESRPHTlGLELR-GVNCG---GTDGDWL-------------EILKQPDVQKTVSGSLVA-------CVI 418
Q18LD4   358 ------CFVGSLTENEYwVDVID-IRQNRiyyGQKIKLA---------------VDQETNLLTCNDKSRRyeqraglSVL 415 Elephantid herpesvi...
Q9QJ20   346 --------KSFLAQDEVwGDLID-CSKGSviyGEKIQWI-------------LDSTNNLYSTRREKQNKSwelyvdcCAL 403 Human herpesvirus 6...
AUI40782 393 ---nsvSAGKTNPSETWyADVVR-CVRAEvnlGVEVHVEt------------CSQSGLWLVRGRDGHLRKwitqpqtYVL 456 Rhesus cytomegalovirus
P16799   457 llfgprNESGPPAEQTWyADVVR-CVRAQvdlGVEVRAAr------------CPRTGLWIVRDRRGRLRRwlsqpevCVL 523 Human herpesvirus 5...
Q8QS07   469 pwlagrGSLPEEPERVWyADVVR-CVRAQvdlGVEVRVRr------------CRRTGLWVARDRRGQLRRwpsqaevCVL 535 Chimpanzee cytomega...
Q997C6   422 -----rYCGRSDPRTEYwADVID-YSRCRvssGLSLRRLagpdgrsaseadaDGDAPLLRLAHLDGRPAEwsadpslCVL 495 Tupaiid betaherpesv...
CAJ86575 416 -------GDLVDGCRVGwADVIW-YAQARvasGIPIKLMr------------VGGDGLWRSFLDSGKLTDwelntdvCVL 475 Murine cytomegalovi...
Q9DWA9   411 --------YERSDGLLGwADVIR-YSSGKvdgGLAVRLVp------------AGPSGLWRSVYDDGEPTGwetdpraCVL 469 Rat cytomegalovirus...
Q9WI09   369 ------TVKLWECGSHDlGQDIShLIKPGigeQGMWEIL--------------LRDPKFKTVVCKSSHv--------CLV 420 Bovine gammaherpesv...
6PPB_KK  419 V-TPALEAWLVLPGGFAIKGRYRA 441
Q18LD4   416 YiNTDLCCIWSFTGGFAVEFRLTL 439 Elephantid herpesvirus 1 (isolate Kiba)
Q9QJ20   404 YvSEKLELDFVLPGGFAITGKFAL 427 Human herpesvirus 6 strain Z29
AUI40782 457 YaTPGLVFHWVLPGGFAISSRVCL 480 Rhesus cytomegalovirus
P16799   524 YvTPDLDFYWVLPGGFAVSSRVTL 547 Human herpesvirus 5 strain AD169
Q8QS07   536 YvTPELHFHWVLPGGFAVSSRLCL 559 Chimpanzee cytomegalovirus
Q997C6   496 YvDRALNVSWALPGGFALTWRLCP 519 Tupaiid betaherpesvirus 1
CAJ86575 476 YaFEDRSLFWVLPGGFCATFQLQV 499 Murine cytomegalovirus (strain K181)
Q9DWA9   470 YaLIDGTLVWALPGGFSAVFALAV 493 Rat cytomegalovirus Maastricht
Q9WI09   421 I-KSLIEAWLILPGGFAIKGSYFI 443 Bovine gammaherpesvirus 4
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap