Conserved Protein Domain Family
tRNA_synt_1c_R2

?
pfam04557: tRNA_synt_1c_R2 
Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
This is a region found N terminal to the catalytic domain of glutaminyl-tRNA synthetase (EC 6.1.1.18) in eukaryotes but not in Escherichia coli. This region is thought to bind RNA in a non-specific manner, enhancing interactions between the tRNA and enzyme, but is not essential for enzyme function.
Statistics
?
PSSM-Id: 398314
Aligned: 69 rows
Threshold Bit Score: 53.4584
Threshold Setting Gi: 573912272
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
EGT58460       162 TKKEVDLRFLELLGPKTAED-LA-PKKKE------KK----AEAPKAAKDTAKtngtssssdnkkkeaastveadfsega 229 Caenorhabditi...
CCX04759       179 LKKEIDAAYLKLLGPKDERDa---PPKKA------PK----AAAAPAAAKEKVeekeatqeis----------------- 228 Pyronema omph...
XP_013024776   171 VKQTLDQKYLELLGPKDERDa---PAGKKgkgnkgKAdtkdQKKGATGSKKSNynmf----------------------- 224 Schizosacchar...
Q9Y7Y8         171 VKQTLDRKFLELLGPKTEQDa---AAGKKkga-kaKN----SKQKTVDSGKAKeqkivseqsk----------------- 225 Schizosacchar...
CCK72963       166 FKPIIDQEVLKMLGPKDERDtVKpKKAKQ------TK---------NQQDGKGkkaqaetakp----------------- 213 Kazachstania ...
ybcl:Ecym_3135 166 FKAIIDREVLKLLGPKDERDvVKkEKKKK-------------------GSKSGgdkgnvsvaggta-----------egt 215 Eremothecium ...
EES00160       173 IKEEIDKRLVEILGPKTEADnIK-PVK--------------KKKEKPAKVEEKkvavataap------------------ 219 sorghum
XP_006643850   173 TKDEIDKKLAEILGPKTDADnVK-PVK--------------KKKEKPAKVEDQkaavvtalp------------------ 219 malo sina
EFA83742       185 IKEEMDAKVLEVLGPKTEADnAP-LPKEP------KA----PKAKPAAAVAADennnspl-------------------- 233 Heterostelium...
EGC32483       165 IKDEVDEAILALLGPKTDADkVV-PAKAK------PA----AAKETANTKDTNnaaaipl-------------------- 213 Dictyostelium...
EGT58460       230 etmdellrtRAHFHKVGENFKTDGYVTTPKTAELLK 265 Caenorhabditis brenneri
CCX04759       229 kdqmfvtgfLAGLHKPGGNEQIIPARMEEH----LK 260 Pyronema omphalodes CBS 100304
XP_013024776   225 -----eegfLAKLHKPGGNPQLIPERMKEH----LE 251 Schizosaccharomyces cryophilus OY26
Q9Y7Y8         226 kynmfeegfLAKLHKPGGNTQLIPERMKEH----LQ 257 Schizosaccharomyces pombe 972h-
CCK72963       214 trsmfsegfLGDLHKVGENPQAYPELMVEH----LK 245 Kazachstania naganishii CBS 8797
ybcl:Ecym_3135 216 krtmftegfLGDLHKVGENPQAYPELMEEH----LK 247 Eremothecium cymbalariae DBVPG#7215
EES00160       220 -pteeelnpYTIFPQPEENFKVHTEIFYSDGNIWRA 254 sorghum
XP_006643850   220 -pseeelnpYSIFPQPEENFKVHTEIFYSDGNIWRA 254 malo sina
EFA83742       234 --pfeiekqSITFPDPSDNIQQTPEILAKH----LK 263 Heterostelium album PN500
EGC32483       214 --dikiereEIKFPDPSDNIQNTPKLLADH----LK 243 Dictyostelium purpureum
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap