5GML


Conserved Protein Domain Family
GRASP55_65

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pfam04495: GRASP55_65 
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GRASP55/65 PDZ-like domain
GRASP55 (Golgi re-assembly stacking protein of 55 kDa) and GRASP65 (a 65 kDa) protein are highly homologous. GRASP55 is a component of the Golgi stacking machinery. GRASP65, an N-ethylmaleimide- sensitive membrane protein required for the stacking of Golgi cisternae in a cell-free system. This region appears to be related to the PDZ domain.
Statistics
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PSSM-Id: 398278
Aligned: 19 rows
Threshold Bit Score: 170.894
Threshold Setting Gi: 146422914
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5GML_A    96 MLIYSSKTLELREASV-TPSNLWGGQ-----------------GLLGVSIRFCSFDgANENVWHVLEVE-SNSPAALAG- 155 house mouse
Q4UCI6    70 LTVYNARKKNIRDVYI-VP-QKWDGI-----------------GLLGLTLKFGLFS-CLDEGAHIVHVY-DKSPAQKAG- 127 Theileria annulata
BAN64805  70 LNVYNARQKSLRLIKI-TP-RKWDGV-----------------GLLGLSVRFAEFT-AMDEGAHVINVH-DGSPAKKAG- 127 Babesia bovis
KIS71167  83 LNVWNSKRQQLRQVSL-VPSREWSSQpstssingtssratsqpSLLGLSLRLCNPSqALSHVWHILEIL-EGSPAESAG- 159 Ustilago maydis 521
Q2HFQ7    78 LGLWSAKGQRTRALHVpVPANT---------------------ASLGLALQWTPVA-VVSNIWHVLDVP-ANSPADAAG- 133 Chaetomium globosum...
Q0U7P0   101 LGVFSAKGQKIREVYIsVPSTN---------------------PTLGISLQWSPLA-LAEDVWHILDVA-PNSPADVAG- 156 Parastagonospora no...
Q2UN33    80 FEIWSAKGQKTHTASIpISPSN---------------------PTLGVALQLAPLS-STQHIWHVLNIPsPLSPAYRAG- 136 Aspergillus oryzae
Q10149    80 LEVFSLKGQITRKVNIkINSDE----------------------KIGMVLQWASIApAVDAIWHILNVI-DDSPVARAS- 135 Schizosaccharomyces...
Q4Q3U9   103 FTTFNLYSRTYRDVYC-VPSDEWGGG-----------------GLLGCSIEWTRADaCPERCVHVVDVL-EGSPAACSTe 163 Leishmania major
Q386P4    73 LTVYNLYIHNYRDVHC-VASSTWGGG-----------------GLLGCSVEWCQAEkCVERCWHVVDVI-PGSPVAKCGe 133 Trypanosoma brucei
5GML_A   156 LRPHSDYIIGAD-------TVMNESEDLFSLIETHEAK-----------------------------PLKLYVYNTDTDN 199 house mouse
Q4UCI6   128 LMPITDYLLGTNl------QLFYDLDCVRIHVANKVDK-----------------------------EVVLIVYNSVTET 172 Theileria annulata
BAN64805 128 LMPITDYLLGTNl------QLFVDSDCVRVHVGERVDE-----------------------------DVTLYVYNSVTET 172 Babesia bovis
KIS71167 160 LVPFGDFVIGWPg------GVLQAEGDFYELVEAHTDR-----------------------------ALRLYVYNSDYDH 204 Ustilago maydis 521
Q2HFQ7   134 LLPYSDYILGTPe------GVLHGEGGLSELVEDHIGR-----------------------------PLRLYVYNNEYNV 178 Chaetomium globosum...
Q0U7P0   157 LLPYGDYVIGSPe------GLVRGESGLGELVEDFLNR-----------------------------PLRLIVYNHEYDV 201 Parastagonospora no...
Q2UN33   137 LLPHSDYIIGTPs------GTLRGESALGELVEDHLDR-----------------------------TLVLWVYNSEFDV 181 Aspergillus oryzae
Q10149   136 LVPYEDYIVGTPe------GMMTGEKALSDLIESHLNR-----------------------------PLRLYIYNHYRDS 180 Schizosaccharomyces...
Q4Q3U9   164 LQANRDYIIGMQtvqetliTLIKSQKDFYCRLEAWHEEqrwalerkqf---------fpnervevphVLLFLVYNSESNT 234 Leishmania major
Q386P4   134 IKEGRDYIIGIQkadelvtALIKDEDDLYTRVELWRTAqsaalrrlqrnsfvptgasredrglqtagQLLLLVYDSVNIE 213 Trypanosoma brucei
5GML_A   200 CREVIITPNSAWGGE--GSLGCGIGYGYLHRIPTR 232 house mouse
Q4UCI6   173 VRRALIVPRENWGGR--GTLGCDLAKGYIHRIPYV 205 Theileria annulata
BAN64805 173 IRKTVITPRHGWGGS--GTLGCDLANGYIHRIPLV 205 Babesia bovis
KIS71167 205 TREVIIVPNREWGGE--GLLGCGVGYGLLHRIPKP 237 Ustilago maydis 521
Q2HFQ7   179 TREVTIQPSRDWGGE--GALGCVLGYGALHRLPAP 211 Chaetomium globosum CBS 148.51
Q0U7P0   202 TRPVTITPSRGWGGE--GALGCVLGFGALHRIPPS 234 Parastagonospora nodorum SN15
Q2UN33   182 VREVELVPTRGWGGE--GALGAELGYGALHRLPVG 214 Aspergillus oryzae
Q10149   181 TRQVTIVPNRHWGGN--GAIGCGVGHGVLHRLPAP 213 Schizosaccharomyces pombe 972h-
Q4Q3U9   235 IEEVEV----EMGTNpeAAVGISVATGLLHIIPSV 265 Leishmania major
Q386P4   214 VKEVLV----DFGNDiyAPLGMNLATGLLHLIPSP 244 Trypanosoma brucei
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