6OZG,3GA2


Conserved Protein Domain Family
Endonuclease_5

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pfam04493: Endonuclease_5 
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Endonuclease V
Endonuclease V is specific for single-stranded DNA or for duplex DNA that contains uracil or that is damaged by a variety of agents.
Statistics
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PSSM-Id: 398276
Aligned: 148 rows
Threshold Bit Score: 167.622
Threshold Setting Gi: 56404424
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6OZG_B          21 NELRKKIKLTPYEGEP----EYVAGVDLSFPGKEEG--LAVIVVLEYPSFK-ILEVVSERG-EITFPYIPGLLAFRQG-- 90  Thermotoga ma...
A8A9B8          13 RKLSELVKEEDCFDPEa--vEAVGGLDVSYKGDVG---VSALSLIDYKTLR-PLKHYYVVA-RVPIPYVPGFLAFREA-- 83  Ignicoccus ho...
jgi:Igag_1924   15 IELSKRVVIEEIDLNRv---DIIAGLDVSYRGNIG---VATAIAYNIKKMK--EECSVSVGgKVEIPYIPGLLAFREA-- 84  Ignisphaera a...
imbp:Hbut_1565  14 KRLSRRIVSSLKPMDTas-iRRIVGLDAAYSKRYGGvaIAALTTR---DGQ-LLTYSVALG-EPPLQYIPGLLAFREA-- 85  Hyperthermus ...
WP_015232175    25 ilFSKKINLNDFINIRdienKVIAAVDASYTKNDLG--IGVAIAFEYPSYN-IIDCELIAR-KVCIPYIPGLLAFREMyl 100 Caldisphaera ...
Q10348          18 IELKGMLQLIPKFQSLne-iRYVVGLDISFDKSSPKa-VSALVIYDLEQRM-IIYKDYLCIeKLEEDYVPGFLSFREI-- 92  Schizosacchar...
XP_001568876   162 STFARQLPAL----------TFVGGVDISFIPGTNDg-VACLAILRYPSME-LVKTYLHRC-TLREPYVSGFLSFREI-- 226 Leishmania br...
EFA80646       301 lkmAASVVKTNSNNLKlsdlKYIGGVDISFAKNNKIdaCASIVVIEYPSLK-VVYESYKMV-KLTQPYIAGYLAFREI-- 376 Heterostelium...
XP_004358966   333 ldktnrVKKLPNGQLn---iKYVAGSDISFAKGNKIdaCASIVVMEYPSLK-VVYESYKMI-KLTQPYIAGYLAMREV-- 405 Cavenderia fa...
EAY07837        15 TEMVVQIDNTKHLDNV----RYVAGADLTVEDDLM---VGCLVVIDMENIDtPVYSKCTVV-NVDVPYIPGLLCFREG-- 84  Trichomonas v...
6OZG_B          91 --PLFLKAWEKLRT----K---P-DVVVFDGQGLAHPRKLGIASHMGLFIEIPTIGVAKSRLY--------G----TFK- 147 Thermotoga ma...
A8A9B8          84 --PLHLTLIKKVKG--------Y-DLLLVDGHGRTHPRGLGIASHVGVTSGVPTVGVAKRRLV--------G-------- 136 Ignicoccus ho...
jgi:Igag_1924   85 --PLMIKALIKLKE----EcieP-DILMVNGHGIAHPRRLGIASHLGVVMDMPSIGIAKSFLY--------G----YID- 144 Ignisphaera a...
imbp:Hbut_1565  86 --PLFYTALRLLDS--------NyDLVVVDGHGISHPRRAGIASHIGIAIAKPSIGVAKKKLY--------G----HEQi 143 Hyperthermus ...
WP_015232175   101 isTPLLKLLKKVK---------P-QVLFVDGHGYAHPRFAGIATHIGIVFDIPTIGIAKKKLV--------G-------- 154 Caldisphaera ...
Q10348          93 --KWYLPLLNHIPHqf------riDIILVDGNGVLHPVGFGLACHLGVLLNLPVVGVAKNYLHcvglteslDahreTLKk 164 Schizosacchar...
XP_001568876   227 --QPVCELIDAVRAelleTqtlP-QVLVVDGNGVLHPRRCGLATHLGIVLDIPTIGCSKKMLRvdg--lgrDavetALAt 301 Leishmania br...
EFA80646       377 --PHLLPLWNDLKRn--aPylvP-QVMVLDGNGINHMRGLGAACHLGVMIDCPTIGVAKQLLVchg--vtnEliedQFNq 449 Heterostelium...
XP_004358966   406 --DHLVALWQSLKRt--hPqftP-DIMVVDGNGVNHMRGMGLACHLGILIDCPTLGVAKNLLVchg--iteEyldeQFDy 478 Cavenderia fa...
EAY07837        85 --PVVLQMLDEFNQantgI---KiDLIIVDGNGEWHTRGLGLASYVGLKSNIPACGVSKTFFYvgeg-cpqPkdvqKMAq 158 Trichomonas v...
6OZG_B         148 MPEDKRCSW-----SYLYdg-------eEIIGCVIRTKEGS---------APIFVSPGHLMDVESSKRLIKAFTLpGR-R 205 Thermotoga ma...
A8A9B8         137 -EEERCGER-----ECLVhe-------gKVVAYVIRRGK-----------QKLYVSVGHCVSLETAYQIVKRLTVr---R 189 Ignicoccus ho...
jgi:Igag_1924  145 ----FIDGS-----KVIIvd-------gRIVGYVVK--KNR---------NEIYVSAGHKIAPHQALKISLETWLdNH-R 196 Ignisphaera a...
imbp:Hbut_1565 144 VSEDCK--------PPCIagyvvdedtgEKLAAIVRTGRSKk--------SRLYVSPGAYTDLDSATTIVLELLEaRKtP 207 Hyperthermus ...
WP_015232175   155 --------------EEVV----------ENNELYLRFKDRLvskillinnKKIYVSPGNKISLENSFNITKLMIG-KF-N 208 Caldisphaera ...
Q10348         165 HVLKKTTDH-----PILIhsid---qssEILGAAVWTSSNSk--------RPVYVSIGNQMNLEQSIQLVQKCSS-SHsR 227 Schizosacchar...
XP_001568876   302 LSEAESSTSslpciVPLLgts----lptQLYGYAVHNHLNSv-------kKCIYVSPGHCVGFAVATALVITML--RY-R 367 Leishmania br...
EFA80646       450 RGNSAT--------IEMRnsm-----nnELLGYAMKNVDS----------ENIYISPGHKMDAKLALEIAKATLN-NR-P 504 Heterostelium...
XP_004358966   479 ATLGEA--------VQMKsdq-----tnELLGYCTYNNEN----------ERLYISPGHKIDAYTALQVYEQTTK-TH-N 533 Cavenderia fa...
EAY07837       159 DKCPEKGDY-----YVLDytts---ndrYIKCAVMRTTDSHp-------fNPIYVSSGHLCDLDSVVSVIKKLC--RF-R 220 Trichomonas v...
6OZG_B         206 IPEPTRLAHI 215 Thermotoga maritima
A8A9B8         190 LPEPIAWADR 199 Ignicoccus hospitalis KIN4/I
jgi:Igag_1924  197 FPEPIYLADM 206 Ignisphaera aggregans DSM 17230
imbp:Hbut_1565 208 LPAPTYHADR 217 Hyperthermus butylicus DSM 5456
WP_015232175   209 LPIPIYLADK 218 Caldisphaera lagunensis
Q10348         228 VPEPIRQADI 237 Schizosaccharomyces pombe 972h-
XP_001568876   368 IPEPIRAADL 377 Leishmania braziliensis MHOM/BR/75/M2904
EFA80646       505 IPEPTFQADK 514 Heterostelium album PN500
XP_004358966   534 LPEPTYIADH 543 Cavenderia fasciculata
EAY07837       221 EPEPTRLADR 230 Trichomonas vaginalis G3
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