5IVA,4RHB


Conserved Protein Domain Family
OstA_C

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pfam04453: OstA_C 
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Organic solvent tolerance protein
Family involved in organic solvent tolerance in bacteria. The region contains several highly conserved, potentially catalytic, residues.
Statistics
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PSSM-Id: 398250
Aligned: 40 rows
Threshold Bit Score: 140.619
Threshold Setting Gi: 81344822
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5IVA_A 125 KDRWL-YGLKNTTGLDS-RWL--------AEVDYTRISDPYYFQDLDTD--------------LGVGSTTyvnqRGTLTY 180 Pseudomonas aeruginos...
O05950 278 KVSSYhYIASGNFISRDqTYD--------YGFRIERTSDKAYLKNYYNNys-----------sYLTSKMFly-kILGADY 337 Rickettsia prowazekii
Q6N5B6 332 DLRGA-VDTKGQFALND-KWV--------WGWEGVLMSDRAFFLDYRLAqyrdswgtflnqstEATSQIYlt-gVGNRSY 400 Rhodopseudomonas palu...
Q2YN48 308 TNRGM-VASKGNFDINS-RWH--------FGWDVLAQTDHNFSRTYEIQgyn---------aqTQVSKIYlt-gINNRNY 367 Brucella abortus 2308
Q92KG5 311 TNRGM-IASRGKFEINP-RWS--------FGWNVLVQSDNNFAKTYDLStfd---------gtTYVNQAYlt-gLGKRNY 370 Sinorhizobium meliloti
Q9A7N2 321 TFRSY-VLANGKFDINQ-HWK--------WGFSAERVSDALLFDKYKINdvyqqrglftsddhRLVSQLYat-rQAQRSW 389 Caulobacter vibrioides
Q5LQN3 281 EDRGY-VFATGQFDLRD-DYK--------LKLGVQTVSDNGYLADYGLPey-----------dRLRSEVSie-rFRRDSA 338 Ruegeria pomeroyi
Q5FU63 299 GVQGY-VFGRANFALDR-NWQ--------LGANINVASSANYMRDYRVPgyg---------qeMLNSNLFle-gYGIGSY 358 Gluconobacter oxydans
O25815 280 NIYGFeFLSSSRDTLQK-YFHlksnidngHYIDFLYMNDLDYVRFEKVNk-------------RITDATH----MSRANY 341 Helicobacter pylori
Q7VIK8 247 HIYGGtFQYETQDIFVSnNEYan----dgFYTDITYMNDLEYMRLKSLNa-------------AFNTRLY----ESRINY 305 Helicobacter hepaticus
5IVA_A 181 --RGDTFTGRLNAQAYQLA--------------TTTDVTPYDRLPQITFDGFLPYNPg----GMQFTYGTEFVRFDRDLD 240 Pseudomonas aeruginos...
O05950 338 --------FAIEVLSFQGLgs-----------nDSKYTDP-LVFPKINTKNVIHLNDn---gDSYIVVENNTLMYKARIG 394 Rickettsia prowazekii
Q6N5B6 401 --------FDIRAIHYLGWaa-----------aDIQGQIP-VVHPVLDYSKTLDQNIfggefSYKTNLTSLSRQTAQFDP 460 Rhodopseudomonas palu...
Q2YN48 368 --------FDLNFYRFNVQesyla-----gdpnEMYSKQP-WVFPSLDYSYTMPEPVyg--sELNFTANLQALYRKNADY 431 Brucella abortus 2308
Q92KG5 371 --------FDLRAFYFDIQdad--------pgsIDENKQP--VAQVLDYSYTAPEPIlggelNADFNLTNIKRNRLDRVn 432 Sinorhizobium meliloti
Q9A7N2 390 --------FSVSAVSVQRLrvvgvtsagtanafENSGTFP-LIGPLVEARWEPEKPVlggrlRLQGSGVMLNRSESQFGE 460 Caulobacter vibrioides
Q5LQN3 339 --------FRIGLIHYETLrd-----------sEIEAEIP-TEIFDINAEKRYFPTGlggevRLAFDGHAHQRQSSANVV 398 Ruegeria pomeroyi
Q5FU63 359 --------MRLDGQAYQGLnq----------gtIRNSDLP-WALPRLTYAFQGQPDMfggrlSVQTTDFNLYRKng---- 415 Gluconobacter oxydans
O25815 342 ylQTENNYYGLNIKYFLNLn-------------KINNNRTFQSVPNLQYHKYLNSLYf---rNLLYSVDYQFRNTARE-- 403 Helicobacter pylori
Q7VIK8 306 fvNTNKHYFGTYFKYYLDLs-------------KESNVNTFQSLPQIHYHHYTDSLFf---kNLLYTFDFQGKYVTRA-- 367 Helicobacter hepaticus
5IVA_A 241 ENIyfnddgsirgkr-------pdaslqglaraTGDRMHLEPGMSLPMTRSWg-yVTPTLKYL--YTKYDLDLDSQGKTD 310 Pseudomonas aeruginos...
O05950 395 EQ--------------------------------VARTSLQLSFMHNVLTSSgqiLNFIAKDR--GDFYLARSSYLDKQ- 439 Rickettsia prowazekii
Q6N5B6 461 VTTianttglclntsadplarlpsscllrgvpgTYTRLTAQADWRRSFTDPYgqiWTPFASLR--ADAIDASISNQPGVS 538 Rhodopseudomonas palu...
Q2YN48 432 TNPfisvdengswvtk-----pnpyprnpgfsgTNLRFTSEAEWKRTFITPSglvITPLLALR--GDAIRVDTNFDPANA 504 Brucella abortus 2308
Q92KG5 433 vlgver---------------------frglegTSHRLTGELEWKRTFIAPGglvLTPLLAAR--GDALGMNVDDPVGYT 489 Sinorhizobium meliloti
Q9A7N2 461 APhflgay-------------------kgqngvDSSRASVKADWRASNIIGPglkVSPFVQAR--GDAYSIKTFVTPAAS 519 Caulobacter vibrioides
Q5LQN3 399 GRD-------------------------------IARATLDAEWLRSWTFASglrADWRMGVA--VDDYRVWDDT----- 440 Ruegeria pomeroyi
Q5FU63 416 --------------------------------iNDQRGEAAIQWDRPFHNKLgqqFLLTARLD--SMVYHATQAYQQPTY 461 Gluconobacter oxydans
O25815 404 ----------------------------------IGYGYVQNALNVPVGLQFs-lFKKYLSLGlwNDLQLSNVALMQSKN 448 Helicobacter pylori
Q7VIK8 368 ----------------------------------SGYKYFQNTFSLPFGVAFp-fFKDYFSIGanVDMYATSVLLQDTQG 412 Helicobacter hepaticus
5IVA_A 311 LNKrd--eSFDSNQDRSLPLVKVDSGLYFDRDTTFagtpFRQTLEPRAMYLY-----VP-YK----------DQDSLPVF 372 Pseudomonas aeruginos...
O05950 440 --------RKNQALQRNIPELQTLWRYPLVGNIKT----INLLIEPIVSFSIgrklsKQ-------------DKQFV-II 493 Rickettsia prowazekii
Q6N5B6 539 NYLl----PGDTQAMRLMPTVGLEYRYPFINVQPW----GTTTIEPIAQVII-----RPnES----------YAGKLPNE 595 Rhodopseudomonas palu...
Q2YN48 505 GFTd---aVVRSEALRAMVTAGLELRWPILFSTTS----STHILEPVAQIFV-----RNnER----------YAGQLPNE 562 Brucella abortus 2308
Q92KG5 490 GNF-----TSSDAETRRMLTAGLEARYPILFAGET----STHVLEPIGQLYA-----RPdEQ----------YAGGLPNE 545 Sinorhizobium meliloti
Q9A7N2 520 ALGd----DTQETYTRALGVGGVDFSLPFYKPLTKg---GSVVLEPLAQVAL-----GSdSSrvpvvvardgTKRYLYNE 587 Caulobacter vibrioides
Q5LQN3 441 --------NYASGTLRSAPRAALTLRYPMVYRGAT----GTHYLEPIAQLGWsdvsgAP-----------------LPNG 491 Ruegeria pomeroyi
Q5FU63 462 YTNa----GGNHLVGQVQPTIALKMNWPFLRSFAKg--hGSQILEPIAQIIA-----APnTGn--------sQNRNIPNE 522 Gluconobacter oxydans
O25815 449 SFVptipnESREFGNFVSSNFSMYVNTDLAREYNK----LFHTIQLEAIFNI------PyYT----------FKNGLFSQ 508 Helicobacter pylori
Q7VIK8 413 ITDam-nhPLNKSINYSVSSYNISLNSDIARPYKH----FFHSMHFEALFSG-------------------------ALY 462 Helicobacter hepaticus
5IVA_A 373 DTSEPSFSYDSLWRENRFTGK-DRIGDANQLSLGVTSRF-IE-ENGfeRASISAGQIYYFRDRRVQLpgltekdlkrlnl 449 Pseudomonas aeruginos...
O05950 494 DPVKYELSEKNIFLSNRYSGI-DCYDFGNRLSYGLNASI-LQeDN---YLKLFLGQSRNTRYSIDLP------------- 555 Rickettsia prowazekii
Q6N5B6 596 DAQTMVFDASNLFSVDKFSGY-DRVEGGGRANVGVQATTqFDqGG---SVNVLFGQSYQLFGLNSFAvada-------tn 664 Rhodopseudomonas palu...
Q2YN48 563 DAQSFVFDASNLFSRDKFSGY-DRVEGGTRANLGLRYSGnFKdSDW--ALYALGGQSFQLGGLNSYAasdf-------vn 632 Brucella abortus 2308
Q92KG5 546 DAQSFVFDATNLFDRDKFSGY-DRIEGGTRANIGLRYTGsFd-SGY--GLRAIAGQSFQLGGLNSFAtddl-------vk 614 Sinorhizobium meliloti
Q9A7N2 588 DSATIEFDETNLFQANKSPGF-DLYEGGQRLNVGGRATF-ARpDGR--GGSILVGRSFRSEFDPLLP------------- 650 Caulobacter vibrioides
Q5LQN3 492 ESNFVEFDQGNLLALSRFPAN-DQREEGKRAVFGLNWAR-FStSGW--QAFATIGQVFRSTSDPRFS------------- 554 Ruegeria pomeroyi
Q5FU63 523 DSLSYEFTDTTLFSLNRYLGT-DRLDGGLRANVGIHQNW--SwNGH--AIDMLVGESFQEHIDHNRL------------- 584 Gluconobacter oxydans
O25815 509 NMYALSAQALNSYTSPLLRDY-DYQGRLYDSVWNPSSILpSNaSNK--TVDLTLTQYLYGLGGQELLyfkis----qlin 581 Helicobacter pylori
Q7VIK8 463 KYTSNAIDDDRYEAYNKLLEEnNHNPEALKVYWNPSDIVdIVkNKH--KVDLKLSQYFYGKNGKELFywrmy----qrlf 536 Helicobacter hepaticus
5IVA_A 450 dPSGLDNDSWRSPYAFAGQYRFNRDWRINSDFNWNPNTSRTESGSAIFHYQP---EvdpgkvvNVGYRYRADARRFDSSR 526 Pseudomonas aeruginos...
O05950 556 ----TDDTENVGQILGNLSNNLEVFYNFRQDRYFRPIRDEVGG---NFNYNK---InflgsfiQLTNLKKYYSVESIKVS 625 Rickettsia prowazekii
Q6N5B6 665 tGLDSGLAKPKSDYVGRVSYSPNSTYKFTTRARFNEATFNVERFEAEASASF---Nrw---svSMIYGNYGAQPDLGFLT 738 Rhodopseudomonas palu...
Q2YN48 633 vGADSGLEDARSDYVAMIGTSNSTGLVLAARGRFGKDDFAVQRGEFEAQQSW---Ekl---tvSGQYAYIAPQPAYGYSD 706 Brucella abortus 2308
Q92KG5 615 aGADSGLETDSSDYVAMLGIDAPSGLMASLSGRLDESDFSLRRADATVGYLG---Lnw---qaALTYTRIEAQPTYGSPF 688 Sinorhizobium meliloti
Q9A7N2 651 --TRTGLQMKSSDWIVAATVTPVRGINAFVRTRLDSKTQDIHRIETGVDAFT---Trg---sgSVRYLKDELDANGNR-- 720 Caulobacter vibrioides
Q5LQN3 555 --KSSGLGGTASDLLLAGQITLPQGLGLTARGLLD-GSLNFSKVEVRGSWTD---Drt---svSGSYLWLGRDLAENRAL 625 Ruegeria pomeroyi
Q5FU63 585 --PYSGLDHHLSDPVGRLRVSPNQYVDVTARGRFNPWTHQFDYGEGLISTGV---Pmf---rlTGGYIYAPVTPYYYYAT 656 Gluconobacter oxydans
O25815 582 lDDKVSPFR--MPLESKIGFSPLTGLNIFGNVFYSFYQNRLEEISVNANYQR---Kfl---sfNLSYFLKNNFSSG---- 649 Helicobacter pylori
Q7VIK8 537 iKDS--FLTRNQVLRNELGFSPIEGLNLSASAFYSYSRNTFSEASINASFNRwglDsnltfyfKLDPLYLSSGLYSQQGS 614 Helicobacter hepaticus
5IVA_A 527 GTFrygnendiIKQHDFSVIWPLVP------------QW 553 Pseudomonas aeruginosa PAO1
O05950 626 NNR--------VRQFYGVINYQLAE------------NW 644 Rickettsia prowazekii
Q6N5B6 739 R----------RQGILGTGTLKIAS------------NW 755 Rhodopseudomonas palustris
Q2YN48 707 L----------RQEVTGSATARINT------------NW 723 Brucella abortus 2308
Q92KG5 689 D----------QDEIQTAAAYRFHE------------YW 705 Sinorhizobium meliloti
Q9A7N2 721 -----------QENFEARGELKLTK------------RF 736 Caulobacter vibrioides
Q5LQN3 626 A----------VSEFWFDGSYKVNP------------YW 642 Ruegeria pomeroyi
Q5FU63 657 N----------FRESGPNAPYLVKTsevtggfsahwrNY 685 Gluconobacter oxydans
O25815 650 -----------INSIVENLR-----------------II 660 Helicobacter pylori
Q7VIK8 615 NNGn-------TGFLRGTMGYDFGY------------FY 634 Helicobacter hepaticus
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