Conserved Protein Domain Family
CHD5

?
pfam04420: CHD5 
CHD5-like protein
Members of this family are probably coiled-coil proteins that are similar to the CHD5 (Congenital heart disease 5) protein. In Saccharomyces cerevisiae this protein localizes to the ER and is thought to play a homeostatic role.
Statistics
?
PSSM-Id: 398224
Aligned: 110 rows
Threshold Bit Score: 111.124
Threshold Setting Gi: 74804651
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
P53192                8 AIFFIVVTK----FLQYTNKYHEKWISKFApgnELS--------KKYLAKVKERHELKEFNNSISAQDNYAKWTK----- 70  Saccharo...
XP_003730057          9 VLIYVAIVHtyrlYIPAISKLILKKLkl--------------vsAQNEDKRKALQDLLDQQSEIDMKEEFAKYAK----- 69  purple s...
EFX73325              7 iAVFILIGS----LLPSIVKWGTHFVfk--------------vsDEEKKIREEFRGLRKELTGISAVDEFARYAR----- 63  common w...
Q7QH65                3 LIFVISLLS----LLMAFASKITKMILPFIcr----------dsAEVIARRKEIAKLRSDLAKISMRDEYTRYVR----- 63  Anophele...
ETN59099              3 LIFVITFIC----FLMAFSSKCTKKITPLLfr----------dsPEVCALKTEIATLRTELSKISMREEYIRYVK----- 63  Anophele...
WGS:AAQB:GK17472-PA   3 LFVLIAIMS----LLNTFLPDFIRNYL------KVSrfwr-lrnEETEILQTELDAAREEVENVRNAEHAGEYAKtikim 71  Drosophi...
WGS:AAPU:GI12412-PA   3 LFVLIALLC----LINTILPDIIRNWV------KISrfw--kgpKVKPEDQAALQAAREELTQVQNAEHSGEYARkiktm 70  Drosophi...
XP_001956886          3 LFALIALLS----LLNTILPDFIRNYL------KVSrlwgsknsKEIQRLQAEVTTAREEVEVVRNAEHSGEYARtiqim 72  Drosophi...
EDW40753              3 LFALIALLS----LLNTILPDFIRNYL------KVSrlwgvrnsAEIRQLQTELNDAREQVEVVSNAEHSGEYARtikim 72  Drosophi...
XP_001624350         16 VLLMRTVFK----SLLAASSWIPKLLnk--------------ptSGEQTSIDELKSMKAEQAIISPQDEFARFVR----- 72  starlet ...
P53192               71 -NNRKLDSLDKEINNLKDEIQSENKAFQAHLHKLRLLALTVPFFVFKIMYGKTPVYKLssSTStLFPTFvsGVWSqgwly 149 Saccharo...
XP_003730057         70 -IERKIIKLKEELKSLKKSQVATRFTVSWGITLALNTIYSVFMIGLIWSYRYEPVILL--EEEwAWPFG--RILA----- 139 purple s...
EFX73325             64 -IQRKMNKLDEQIQSLGQSRMDGRESVRWKLTKAIQVVNGAVLVYLAVTQRYEPVLTG--LTDwFWPLN--LLLS----- 133 common w...
Q7QH65               64 -CEREIGKLEVTLNEAKGRDGVKRVAYEYGLHYGGMAVVGLCMMYISIFYRYSTVIVFgdNFN-FEPFG--GFIN----- 134 Anophele...
ETN59099             64 -CERTVVALETKLNEAKERDNVTRVMYEYGIQYGSMAVLGLVLICISFYYRYTPIIVFgnNFN-FAPFG--WFIK----- 134 Anophele...
WGS:AAQB:GK17472-PA  72 rAERKVNEIELKIKTAQQLETLKKSTIDTISYYVSKLVMTLILIIISVRNRTSPVMILdkQIN-LWPLE--DLLS----- 143 Drosophi...
WGS:AAPU:GI12412-PA  71 rAERKVADAESKILRASQMQKLKQSTIDTVAYYVTKVVFSLVVIIVCARHRYSAVMIFdeSFS-LQPLS--GLLS----- 142 Drosophi...
XP_001956886         73 rAERKVQEAEANLKSARGMENLLKMGIDTTAFYVSKVLLFIITFIVSVRNRGTPVMIIdeAIS-LAPFT--GLLS----- 144 Drosophi...
EDW40753             73 rAERKVSEAEAKLKSARGMENFMRMSIDTAMFYGSKVLLSAITVFISIRNRGTPVMIIdeAIS-LAPFT--GLLS----- 144 Drosophi...
XP_001624350         73 -LKRKIDKVSEDLIEKAKSRNEKIGKQQRSLKGIFLMCLFAVHIVFLVTYRKTPIVQL--PEPwFSPLH--SIIS----- 142 starlet ...
P53192              150 VLLHPLRtisqkwhimegkfgaskfddmalqSVSLGIWVWALM 192 Saccharomyces cerevisiae S288C
XP_003730057        140 FPCGIPG------------------------AVGITAWLAVCS 158 purple sea urchin
EFX73325            134 YPTGIEG------------------------ALSIVFWLFICN 152 common water flea
Q7QH65              135 FPTKVPN------------------------SISVVFWIVVnn 153 Anopheles gambiae str. PEST
ETN59099            135 FPTDVHN------------------------SISVVFWIVVnn 153 Anopheles darlingi
WGS:AAQB:GK17472-PA 144 FPTGIDH------------------------AVSVPIWAFSCN 162 Drosophila willistoni
WGS:AAPU:GI12412-PA 143 FPTGIYN------------------------AISVPTWALSCN 161 Drosophila mojavensis
XP_001956886        145 FPTGVAN------------------------AISVPAWAFSCN 163 Drosophila ananassae
EDW40753            145 FPTGVAN------------------------AISVPAWAFSCN 163 Drosophila sechellia
XP_001624350        143 FPTGTIG------------------------AIGLPFWMVTCN 161 starlet sea anemone
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap