Conserved Protein Domain Family
DUF521

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pfam04412: DUF521 
Protein of unknown function (DUF521)
Family of hypothetical proteins.
Statistics
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PSSM-Id: 398218
Aligned: 112 rows
Threshold Bit Score: 359.925
Threshold Setting Gi: 523986789
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCX70779                       1 MLLTPEQQAMLNGEKGETMAKVVKTLVMYGETFGAKRMVPITSKYGHTVISFGlkVMKPVYDL-------------YQEI 67  Firmicutes bacterium CAG:555...
WP_015435599                   1 MKLTTYEQEMLDGKHGEGKKFAMEKLVDFGRAVGAEEMVPLTFVHYIGC------VKDLPRDTpeyqqfewgqglqLEPL 74  Azoarcus sp. KH32C...
Q2FQH8                       170 ISLTPYEQEMLAGKHGRPKQVAMERLVKFAEGMGSKRMVPICSAHLFD-DHQSrdYTVGAWPA-------------FEEF 235 Methanospirillum hungatei JF-1...
WP_013705756                 175 LKLTFYEEEMLYGKHGRAKQAAMERLVEFGQGMASKRMVPICSAHVFS-DWKNydLVIGSWPL-------------YEEF 240 Desulfobacca acetoxidans...
CDF42037                       1 MELTEEQKDMLNGRYGEGTAYAMKIQVAIGESFDAPRMVPITRAHVALSNQ------DADLWF-------------AEKL 61  Roseburia sp. CAG:182...
csisp-ryc-ciber-uv:acin_2275   1 MKLTQDQQDLLDGKFGEGAKLAMKVQVAIGESFGAERMVPITRAHVALSNQ------DADRWL-------------AEKL 61  Acidaminococcus intestini RyC-MR95...
CDE13631                       1 MKLTKEEQAMLDGEFGAGVQLAMKIQVAIGEAYDAPYMVPVSRTHVALSNQ------EADLWF-------------AEKL 61  Ruminococcus sp. CAG:330...
WP_013074951                   1 MYLTAEEQAMLDGEFGEGAALAMRVLVGIGEAFDAPRMVPIRRAHVALSNQ------EADLWF-------------VERM 61  Kyrpidia tusciae...
jgi:Anamo_1977                 1 MFLEDDEKRMLDGDYGPGVQKAMELLFALGKAFDAERLIPVSRTHVALSGQ------EGDTYW-------------CTLL 61  Acetomicrobium mobile DSM 13181...
WP_006299793                   1 MRLSDEQKRMYDGSRGPGVQKAMELLVALGKAFDAEEMIPVSRTHVALSGQ------EGDTYW-------------CELL 61  Aminomonas paucivorans...
CCX70779                      68 IDAGLTAD----QKFTADPKPLD-----KH-----VPSSLIEdlVFKKFmytvQDDYEKql---vqLGITSddDYTCTCY 130 Firmicutes bacterium CAG:555...
WP_015435599                  75 FKMGAKVTedphVTCSTDPFLHQldayeKTgt--pWNNKFYK--LPKIV----HEASVRgyeamkeAGWVP--THSCTPQ 144 Azoarcus sp. KH32C...
Q2FQH8                       236 ASMGAKVV----VPTTVESTAMGddlvdDKg----MPWHYSVmaPAREV----FKGMVPvhenlknMGATV--IPTCIPY 301 Methanospirillum hungatei JF-1...
WP_013705756                 241 AALGAKVA----VPTTVESTVMAdelvhDQg----MPWHYQVmmPAGEV----YAAMRPvhealkdMGVQV--IPTCIPY 306 Desulfobacca acetoxidans...
CDF42037                      62 LHAGAHCR----VSPTVNPgfc----isFFkqhnmVSDEDTE--MMQRT----HNAYKG-------LGATL--TYNCTPY 118 Roseburia sp. CAG:182...
csisp-ryc-ciber-uv:acin_2275  62 AGLGAKCR----VRPTVNPgfc----lsYFkkmgvVTNKDYE--EMERT----DRAYRA-------LGAEL--SYNCTPY 118 Acidaminococcus intestini RyC-MR95...
CDE13631                      62 VAGGATCR----VRPTVNPsfn----weQLscvtkLEPEDEA--IVKRT----HAAYNA-------LGAIM--TYDCTPY 118 Ruminococcus sp. CAG:330...
WP_013074951                  62 VGLGARCR----VAPTVNPgfd----leYFnraaaLEAGDVE--QMERT----YRAYRA-------IGAVL--NFSCTPY 118 Kyrpidia tusciae...
jgi:Anamo_1977                62 ADGGAKCK----IAPTTNPawd----vnALskrfeVTEAELD--LAVRT----IDAYRR-------IGAVL--SFCCTPE 118 Acetomicrobium mobile DSM 13181...
WP_006299793                  62 VNGGARAV----VPPTTNPawd----tqTLtrhydVTPGELD--LALRT----VDVYRR-------IGAVL--TFCCTPE 118 Aminomonas paucivorans...
CCX70779                     131 LdQvGNKPNKGDILSWAESSAVVYANSVLGARCNRNSGMIELMGSIAGFVPEFGLLLDEERKATWVVEvk-----ceHKP 205 Firmicutes bacterium CAG:555...
WP_015435599                 145 F-N-TVMPKNGEYAASCESSCATYLNTIMGVKTNRENAVTGMYAAYTGCLPKYGMLIEENRRPKIIFDlddeikeniVDD 222 Azoarcus sp. KH32C...
Q2FQH8                       302 A-H-LAPPKFGEYLVTSESNAAAYSNIMIGARVNRDPANMVLYAAITGVMPEYGVHLQENRIGQMIFDvdpa-vvkeLDD 378 Methanospirillum hungatei JF-1...
WP_013705756                 307 M-H-LTPPRFGEFHVTAESNHAAYANIMLGARVNRDPANMVFYAAITGIMPEYGMHLAENRRGQMLFEvapd-llpeLQD 383 Desulfobacca acetoxidans...
CDF42037                     119 V-A-TNVPNFGEICAFSESSATPYINSVWGARSNREGANSALCAAITGYVPEYGLLLDENRKGNVLVEvq-----adMKS 191 Roseburia sp. CAG:182...
csisp-ryc-ciber-uv:acin_2275 119 M-D-TNVPLFGEICAFSESSATPYVNSIWGARSNREGANSALFASITGYVPEYGLLLDENRHGNILVQve-----adIKC 191 Acidaminococcus intestini RyC-MR95...
CDE13631                     119 L-E-KNVPRFGEICSFSESSCTPFMNSVYGARTNREAAQSALCAAVTGVVPYYGYLLDENRKGEILVHve-----adMEN 191 Ruminococcus sp. CAG:330...
WP_013074951                 119 L-L-DNIPRQGEVVAFSESSATPYVNAVYGARSNRESAQSALCAAVAGRVPEYGLLLAENRRGQIVVDvk-----aeLSS 191 Kyrpidia tusciae...
jgi:Anamo_1977               119 L-E-SNVPVFGEHVAFSESSATPYVNSVLGARTNRESSVSALASAVIGKTPLYGLHLSENRVGQFMVLve-----aeMKD 191 Acetomicrobium mobile DSM 13181...
WP_006299793                 119 L-A-GNVPTFGEHVAFSESSATPYVNSVLGARSNRESSVSALASAVTGITPLYGLHFRENRLGTFLVDve-----aaPKE 191 Aminomonas paucivorans...
CCX70779                     206 EAQL--LGSAIGMKVM-EEVPYVK---GLDKWlgtELDDeacayLKDFGAATASNGAVGLYHIENLTPE----AVEQG-E 274 Firmicutes bacterium CAG:555...
WP_015435599                 223 SADWaaLGGAIAMKVNfRGIPAVT---NMPERl--TTSA-----AKALTACASPGMNDPMLHLIGITPGsstlEEAFGgA 292 Azoarcus sp. KH32C...
Q2FQH8                       379 VGDYvaLGGAIGFRAG-DRVPVVC---GLNRM---TNAQ-----AKAFCACVSPALTYPMIHIVGITPEartiEEAFGgE 446 Methanospirillum hungatei JF-1...
WP_013705756                 384 VGDYvaLGGAIGFRAV-DRVPVVL---GLNHL---SNEQ-----GKAFCACVSPALTYPMMHIVGVTPEartmEEAFGgP 451 Desulfobacca acetoxidans...
CDF42037                     192 DFEYhlLGY-CGKKIG-PGIPVFT---GLPKHi--GKEA-----LTNLGAQLNTSGAYGMYHIAGFTPEaptvEAAFG-G 258 Roseburia sp. CAG:182...
csisp-ryc-ciber-uv:acin_2275 192 DADYhiLGM-CGKKIG-HGIPVFA---GLPKNi--TKEA-----LRNLGAELNTSGSYDMYHIPGFTPEapdiKTAFG-G 258 Acidaminococcus intestini RyC-MR95...
CDE13631                     192 DFDYqlLGYFAPQKIG-FKLPVFT---GLKNP---TKES-----LMNLGAQLNTGGNVAMYHIVGFTPEaptiEAAFH-G 258 Ruminococcus sp. CAG:330...
WP_013074951                 192 DFDYqlLGYAVPKKIG-HRIPVFV---GIPDTa--SPEA-----LMNLCAELNTAGAVPMFHIVGLTPEaptlEAALG-G 259 Kyrpidia tusciae...
jgi:Anamo_1977               192 PYDWgiLGWYIGRFAG-YRIPVIRfvnMKQRP---APED-----LLYMGAEMNTSGAVPMYHIEDVTPEal-mQKHLT-A 260 Acetomicrobium mobile DSM 13181...
WP_006299793                 192 PYDWglLGWYVGKRVG-AQVPVFRfrnLQGRP---SPEA-----LLYLGAELNTSGAVPLYHILGVTPEapdeAVAFG-G 261 Aminomonas paucivorans...
CCX70779                     275 SII-AE-NAqvyVIDDAELERVKASYpviWKNPDADPQLCFVGCPHLTLRQLIDWTQNVgkqltANGLKKVTVPTVFTAS 352 Firmicutes bacterium CAG:555...
WP_015435599                 293 VPAdVE-RI---RLTLDDVRQCYEHL---RTAKTDKVDIVHMGCPHLTYEEIRQIARAI-----KGKKVHPEVMMWVQTD 360 Azoarcus sp. KH32C...
Q2FQH8                       447 IPKdVE-RV---RITKSDLAAVYQNL---RQTEKTSIDAAVIGCPFLMFEELADIAGML-----DGQKV--SAPLWLYTD 512 Methanospirillum hungatei JF-1...
WP_013705756                 452 IPKdVE-RI---SIGKQEIRELFHNT---RQTDRQDIDVGVIGCPFLTFQELAGLAELL-----DGRTV--KKRLWLYTD 517 Desulfobacca acetoxidans...
CDF42037                     259 KEP-ER-KV---VITNDDLQEILEEI---SNPGNRKIDFAMFGCPHFTLDQAMHIAERI-----DGKKL--AVPMWILTS 323 Roseburia sp. CAG:182...
csisp-ryc-ciber-uv:acin_2275 259 KEP-ER-VV---TITNDDLAEVLESI---SLPGHQPIDFAMFGCPHFSFHECDHILKQL-----NGRKL--AVPMYILSG 323 Acidaminococcus intestini RyC-MR95...
CDE13631                     259 EEV-RE-EV---TITNDDLRSMQSML----TDPYGKIDFALFGCPHLTIDQIGVIAEMV-----RGQKL--AVPLFVMTS 322 Ruminococcus sp. CAG:330...
WP_013074951                 260 REP-VD-TV---TVTDRDLLEVREQI----SQAPGQVDFVLLGCPHLSLRQLQTIAELV-----RGKKL--RVELWINTS 323 Kyrpidia tusciae...
jgi:Anamo_1977               261 GKA-LDvEL---VIGDRELKDQQEEL----FEKIGPINLVMLGCPHYTYAQIREVERLM-----SGRHVKKGVDFWILTS 327 Acetomicrobium mobile DSM 13181...
WP_006299793                 262 HRP-AG-SL---SVTDRNLEEQEAEL----SEKGGKINLVMLGCPHYSYAQLRELDRLL-----AGRTV--SVPFWVLTS 325 Aminomonas paucivorans...
CCX70779                     353 TPVIKEFEKTPYAKQLKRQGI-ILSYICPLMymnNPLCK----KKAVITCSNKLRTYTSARYYTEAEI 415 Firmicutes ...
WP_015435599                 361 TPSYNMARHYGEAAIIEEAGGkIYHQTCAGM---NMLSVdwgsGFNVATNSFKQVKIFGGLG-HSMIF 424 Azoarcus sp...
Q2FQH8                       513 YVNYSAAKKAGILEKIEASGArVVHSSCPGMvvrAPADAe---KLVFATDSLKVAMLFAGIGWPKNWL 577 Methanospir...
WP_013705756                 518 YVFYSAAKKAGLLARIEKSGArVVHSCCPGMiirDASAAe---SLVYATDSLKVARLMSGIGWPKNWL 582 Desulfobacc...
CDF42037                     324 YHVKELADRMDITEKIEKAGAfIVPDTCp----dQPCWHgl-kGKIGVTESPKCAYYLKRRG-IEFVI 385 Roseburia s...
csisp-ryc-ciber-uv:acin_2275 324 EHVCEMTKRTGIYDELEALGAhVIPDTCp----dQPCWHfl-kGKIGITESPKCAYYPQRRG-IRFVI 385 Acidaminoco...
CDE13631                     323 GLSLDLAKKMGYEETIRQAGGhIFSDTCm----dQPCWKfl-yGKKGVTDSPKCAYYTRRRQ-MEFVV 384 Ruminococcu...
WP_013074951                 324 AYTREVAARMGLVDVIERAGGhVLQDTCv----dQPIWKhl-eGKTGATESPKCAYYTKRRQ-MNFVI 385 Kyrpidia tu...
jgi:Anamo_1977               328 FYTLELTTRSGERSRLKDLGVeLVADTCi----dEPCWKsf-eGGLGMTDSPKCAYYRKRRG-QPFVV 389 Acetomicrob...
WP_006299793                 326 GDAMELARRSGELARIEASGArLVPDTCi----dEPCWKsf-eGGLGVTDSPKCMYYRERRG-QPFVI 387 Aminomonas ...
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