1D3Y


Conserved Protein Domain Family
TP6A_N
?
pfam04406: TP6A_N 
Click on image for an interactive view with Cn3D
Type IIB DNA topoisomerase
Type II DNA topoisomerases are ubiquitous enzymes that catalyze the ATP-dependent transport of one DNA duplex through a second DNA segment via a transient double-strand break. Type II DNA topoisomerases are now subdivided into two sub-families, type IIA and IIB DNA topoisomerases. TP6A_N is present in type IIB topoisomerase and is thought to be involved in DNA binding owing to its sequence similarity to E. coli catabolite activator protein (CAP).
Links
?
Statistics
?
PSSM-Id: 427928
Aligned: 173 rows
Threshold Bit Score: 50.552
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
1D3Y_B         7 IFAQTTKMLEFAKQLLETDDFSTLREAYYVsknwGEARFDDQQASNNVIEDLEAALGVLREHLGF 71  Methanocaldococcus jannaschii
Q3SD96        54 ELCHYLIVMRVSLDGILNDSYHTKREIFYM----NQNVFQKQENLNLVIKQFSHNIQIQRKQLHI 114 Paramecium tetraurelia
ESS30356      64 KLTWVLSLLDQIHGLLMTNRAATQRELFYG----LVNVFDTQAQVNAQLQQIVSWLEIPRDSLNV 124 Toxoplasma gondii VEG
XP_001608493  53 GLCRTVSVVELVNDMVIQDKSCTQREIYYK----LYHLFSEQCQTNRHILHVCHILGFPRASLNV 113 malaria parasite P. vivax
CZT98530      54 NLCRTVSVVELVNEIIMKDKNCTQREIYYK----FYNIFREQNQANKHIKDVCNILGYERSSLNI 114 Plasmodium falciparum 3D7
EFC39811     122 KNHLVWLLMKDVHLLLNCRKKITQRELFYM----NVTTFRDQIQCNRCLSTVGDVLKVDRSLLNI 182 Naegleria gruberi
ESS31438      48 TVARWVVMMKQIIMLIQMKTHATIRELFYS----SIRTYSTQVVTNRILAKVTQFLGVPRETLHV 108 Toxoplasma gondii VEG
Q8I5N7        37 DITRLFYIIQIILINIKNNIYTTLRQIFYT----NPKLFINQRNSNKIIGKLTKIIKTSREQINI 97  Plasmodium falciparum 3D7
Q5CW77        54 NSTCLVSVMNILHRNVKEGFHSTLRDIYYN----NPSLYTKQSISDKYIAQVTHLVQTPRELLNV 114 Cryptosporidium parvum
XP_002139871  46 QMTCIISITNTLHGLVSEGYHATLRDIFYS----NPSLYKKQTVSNNTIAMITRLIRIPREFLNV 106 Cryptosporidium muris RN66
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap