2BZT


Conserved Protein Domain Family
Fe-S_assembly

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pfam04384: Fe-S_assembly 
Iron-sulphur cluster assembly
This family of proteins is likely to be involved in the assembly of iron-sulphur clusters. It may function as an adaptor protein. In Escherichia coli IscX forms part of the isc operon, which encodes genes involved in iron-sulphur cluster assembly. Its structure is entirely alpha helical, and it contains a modified wing-helix structure, usually found in DNA-binding proteins. It binds to Fe2+ and Fe3+ ions and to the cysteine desulfurase IscS, the same surface of the protein is involved in both binding to iron and to IscS.
Statistics
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PSSM-Id: 398196
Aligned: 86 rows
Threshold Bit Score: 85.251
Threshold Setting Gi: 332331067
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2BZT_A            3 LKWTDSREIGEALYDAY-PDLDP---KTVRFTDMHQWICDL---EDFDDDPQASNEKILEAILLVWLDEAE 66 
jgi:Terro_4173    5 ygWEETEEIGIQLQEKY-PEIDP---LTVRFTDMHKYITEL---PGFTGDPAKSNEGLLEAIQMAWLDEYN 68  Terriglobus roseus DS...
WP_014263592      5 INWTDTLEIGIQLQEMF-PDTDP---YSVRFTDLHKWVTQL---PGFVGDPTKSTEGILEAIQTAWHEEYv 68  Granulicella mallensis
jgi:AciX9_3513    5 IQWTDAEEIGIQLQEKY-PEIEP---YTVRFTDLHKYVTEL---PGFVGDPMKSTEPGLEAIQKAWYEEYE 68  Granulicella tundrico...
jgi:AciPR4_3970   5 fDWTDSEEIGIQLEEKY-PGEDP---LAIRFTDLRQRVLDL---PGFIGDPAKSNEGILEAIQMAWHEEYE 68  Terriglobus saanensis...
WP_015897624      5 ITWNDAEEIGIQLQEKF-PDLDP---LSVRFTDLHKHVTEL---EGFADDPSKSNESKLEAIQMAWYEEYK 68  Acidobacterium capsul...
jgi:Solca_0898   10 IKWNDYEDIAMGLYDKFgDDFSEpkiYRIRFTELMEWVLSL---PNFKGTKEECNEGHLEQIQSAWVYEWR 77  Solitalea canadensis ...
WP_015691496      9 IHWTDYEDIAMGLYDKFgDDFTEskiYRIRFTDLIEWVLDL---PNFVGKREDCNEGHLEQIQAKWVYEWR 76  Saprospira grandis
jgi:Halhy_0256   11 ITWTDHEDVAMKLYERFgDEFAEgkiYRIRFTDLIEWVLEI---PNFVGTREECSEGNLEQIQAKWVYEWR 78  Haliscomenobacter hyd...
Q8ID90           67 LHWENAEDIADMLFEEY-RNIDP---LTLRFEQLENMIIDTvvkKNKRQLNGHCNEGVLENIQMNWLEKYN 133 Plasmodium falciparum...
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