Conserved Protein Domain Family
RdgC

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pfam04381: RdgC 
Putative exonuclease, RdgC
Members of the RdgC family may have exonuclease activity. RdgC is required for efficient pilin variation in Neisseria gonorrhoeae, suggesting that it may be involved in recombination reactions. In Escherichia coli, RdgC is required for growth in recombination-deficient exonuclease-depleted strains. Under these conditions, RdgC may act as an exonuclease to remove collapsed replication forks, in the absence of the normal repair mechanisms.
Statistics
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PSSM-Id: 427910
Aligned: 96 rows
Threshold Bit Score: 268.986
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Fbal_2803   1 MWFKNALPYRLTKPIDWQADELERQMEALAFTPAGSQEMAKLGFVAALGPKVGggLVHVADGNLLIAIEKEEKMLPASVI 80 
WP_015045786    1 MWFKNLQVYRLGDGHSIDLSTLAEQLEQDRFAPCSQQAQFSLGWASPYGKHHPg-LAHLGQNAALISLRREDKVLPAAVI 79  Simiduia agari...
Q3II43          1 MWFSNLICYRFKQDVSYTQEDFDKALEQDLFRPCTGQELATFGWTKAFGKHGEt-LSHFSQKSILVCAKREEKVLPASVI 79  Pseudoalteromo...
WP_007640263    1 MWFKNLKLYAITQDMDFKEQDFEDKLAEFKFRPCGSQELATMGWASPFNQGET--LIHATAGRIWLTLKKQERILPAVVV 78  Paraglaciecola...
SDU:GNIT_2813   1 MWFKNLKLYQLTNTLELTEEQLQTQLESMSFRPCGSQDIATMGWTSPFRNSDM--LFQKTANRYWLVLKKEERILPASVI 78 
Q2SCW6          1 MLFKNALIYRFTKPVPWPLEDLETGLSEHAFTPCQANDTYRLGWVPAAPLVSDa-LVYQQGRYLLLTLKREEKILPASVI 79  Hahella chejue...
Q5NFX9          1 MFFKNLTAFKITDI---NIDIFEDSMNKLAFIPCSNPQKSSRGFINPFIKDEN--CLFKFNHLAAFCLLTEEKILSAQVI 75  Francisella tu...
WP_012823905    1 MFFRQLSVYRLESECP-DFSTLNTALKEHPFSPTRPQQAESVGWQTAIGEQY----VHETDGAARIVLQREERSVPSSVV 75  Halothiobacill...
WP_025385626    1 MWFSNALIFQYDFD---KPFDLTTALANESLKPCPPHARFIYGWLPAHADE----LVQEVAGSMLICLGKEERLLPRSVI 73  Legionella oak...
Q5NWY5          1 MLLRSAFVFSCDCPH--SPEELEEVLASRKFSGIGQLDVDHLGWVNPRELENGp-LVHAVDSIFLLALSKETKIVPASTV 77  Aromatoleum ar...
jgi:Fbal_2803  81 KEELDERVGQLENEQGRPARKAEKEAMKEDIVAMLLPRAFSRRKRIRALVMPRQQLILVDSSSAARAEELLSLLRQAI-- 158
WP_015045786   80 REMVEEKAAAIEAEEQRRVYRKEKEQFKEEILFECLPRALRKSRRTQAIIDLEAGLIIVDAASPNRAEELTSTLRQSL-- 157 Simiduia agari...
Q3II43         80 NELVAEKVDLIEAEENRPVKKKEKDELKENILHTLLPQAFKKSSLQFAFIDQENGWVVVNSGSFNKAEELLALLRKSL-- 157 Pseudoalteromo...
WP_007640263   79 NAELADKVALIETETGSPVGKKAQQDMKQEIIHRLLPQAFTKNSYTHGFISTQDHLVVVDSSADGKAEAFLAMLRKAI-- 156 Paraglaciecola...
SDU:GNIT_2813  79 NNELAEKVAQIEAETGSPVPKKSQQDLKQEIVHRLLPQAFTKNSVTHGFISPEHNLVVVDASSDGAAEAFLSCIRKCI-- 156
Q2SCW6         80 KEEVEERAQEIEEREQRKLRKKEKNELKEQVITVLLPQAFKRSRLMSAYIDLDKGLLVVDTSSGTRADEFTSFLRQSM-- 157 Hahella chejue...
Q5NFX9         76 NQQAQEYIEELELTR--YVSKKEKTQIKEDMQQKLLPLAFSKFRKTYGYLDLTNNYLVIDSISEKQITEILDLLHRCE-- 151 Francisella tu...
WP_012823905   76 RDMADQRLLARAGTTG-EPSKAEKIAMRDAVLLELLPQAFPRQSNTQAIIDRKNQQVWFDTLTATKIERTSNQLREQI-- 152 Halothiobacill...
WP_025385626   74 HKMLAERVQTWESQQGRTMKRAEKAQLAEELEFELLPKSFCLQKRMFALLDTVSKRLIINTASNNQAAQLTALLRKSL-- 151 Legionella oak...
Q5NWY5         78 KKKLAAAEADATKREGRPPSRKERKALKEQVYESLLPGAPTRIKQTFGVLIPPKKQLLVLTTSAKCLEDFHGVFTDSFmk 157 Aromatoleum ar...
jgi:Fbal_2803 159 -GSL-P-VAPLMPNTLPEEAMTDWVRTG-NIGHNLTLLEEAELKSLAEN-GGSVKLKDLPLDSDEVTAHLDAGLLAVKVG 233
WP_015045786  158 -GSL-P-LTPVQYNYSPATVMTQWVNGE-PLPEEWKLGQECELREPGEE-GAILRCRRHDLLCDEIQSHLAAGKQVAQLA 232 Simiduia agari...
Q3II43        158 -GTL-P-VVPAFANYDLDVFLTDWLTNF-STPEGFAIGSDAELEEADDS-GAQVKLKGHDLSCDEVKSHLETGKRVTKLA 232 Pseudoalteromo...
WP_007640263  157 -GSL-P-VVPL-ARHSVHADLTSWLKDD-SAPTDISILEEAELKALEED-GAIIRCKNQDLYSEEITHHLEAGKSVQKIA 230 Paraglaciecola...
SDU:GNIT_2813 157 -GSL-P-VVPF-AKSSKQETLTSWVMQD--APEQIEILDEAEFKSPSED-GATIRCKSQDLDAPEILAHLQSGMLVQKLS 229
Q2SCW6        158 -GTL-P-IRFVALNEAPAVHFSDWVQKD-STPTPFVSGDNCELRSGDGS-DTVIRCKGTESLTDAISTHIENGMQVTQLS 232 Hahella chejue...
Q5NFX9        152 -ARFeP------VIKEETDILTEWLVDN-AYPVDIEIAEKCKLTSAIGDsIANISCQGSSMLNDNIKSFIDSGGYITEIA 223 Francisella tu...
WP_012823905  153 -GQW-R-MVPFFGIQDISAHLASWLLG--TPPTGFDIGEGAKLVDLRE--GGTVTVSKLALPDPHVVAHLHEGMKVDQLE 225 Halothiobacill...
WP_025385626  152 -PGI-S-IEPLQYSENLSHHFAEWINHPtTLSSAFQLASDCLLFSPDDE-KKRFNCKGYELPAEEILTLLSQGLAPAEIS 227 Legionella oak...
Q5NWY5        158 rGMR-PsFRKLRTVQPPSLKMTEWLLNN-ECDGGFVLGEHCELTHE----KSKVRYTALELDRPEIREHLLEGKVPVKLG 231 Aromatoleum ar...
jgi:Fbal_2803 234 LDWAESVSFVLS-----ADLSVKRIKFADVLQDQNDDiDK-ADLAARYDADFALMCGEFERLWPDLLASMGGV 300
WP_015045786  233 LNWREQLQFLLT-----QEGTIKRLSLGDDLKQEARD-SA-EDPLSQLDAEFSLLLLSLRQLLPEMASALGDL 298 Simiduia agarivorans
Q3II43        233 LDWQERVKFMLQ-----NDGSIKRLSYSDTLKEENADiPK-EDMAVKLDADFILASEEIKQLLEELTQGLGDI 299 Pseudoalteromonas tra...
WP_007640263  231 VEWNETLTAIIQ-----EDLSIKRLKFTDVIREQNDDiPK-DQMLARLDANFALMSGEVVRFAKRLKEIFKLd 297 Paraglaciecola psychr...
SDU:GNIT_2813 230 VAWQDRLTCIIG-----EDLSIKRLKFTDVVKEQNEDiPK-DEINVKLDADFTLMSGEVVEFAEALRKIFDVE 296
Q2SCW6        233 LEWDEKLSFAVG-----DDLKIKRIKFMDTLQEQLKDgDT-GEAAERFAADFSLMTLEFSRMTDDLIKVLGGE 299 Hahella chejuensis KC...
Q5NFX9        224 IIWREQLAMTVN-----TKLQFKAIKFLDGIKDLN------KEDNSGHEVDLLLMADIFAELINTMQNWIVEe 285 Francisella tularensi...
WP_012823905  226 LIWREQIRFTLR-----ADGGLAKIKPTE-LLDTDDSgEMiDDADQQLDADQRLMVGALRQLIQDLANVLKDn 292 Halothiobacillus neap...
WP_025385626  228 LIWNERIQFTLT-----HDFTLKRIKCLDYLLDEFNEiGQlEEDYQQQDAALTLLAGELRSLINDLLEVskqp 295 Legionella oakridgensis
Q5NWY5        232 LRHESTTSFIIScgsadEDLGFSKIHYGDNDGKTEGE----GTADEVFDSDLVFSVTEFLGIVNELFEAFGGI 300 Aromatoleum aromaticu...
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