Conserved Protein Domain Family
BMFP

?
pfam04380: BMFP 
Membrane fusogenic activity
BMFP consists of two structural domains, a coiled-coil C-terminal domain via which the protein self-associates as a trimer, and an N-terminal domain disordered at neutral pH but adopting an amphipathic alpha-helical structure in the presence of phospholipid vesicles, high ionic strength, acidic pH or SDS. BMFP interacts with phospholipid vesicles though the predicted amphipathic alpha-helix induced in the N-terminal half of the protein and promotes aggregation and fusion of vesicles in vitro.
Statistics
?
PSSM-Id: 398193
Aligned: 141 rows
Threshold Bit Score: 49.4084
Threshold Setting Gi: 123323345
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
jgi:Marme_3435   3 DQFVKQMGAGLEQAAAtlgkLpAEEIQQQLHQVAKDTLTKMDLVTREEFEVQADMLAKYRKRLLELEARLEELEK 77  Marinomonas medite...
WP_012284748     9 DEFAKLTQAAMGIAQT----A-GEEAKTAMRAQADRLAAEFDLIRRDDFEALKAEVAALREDVAALKAKKApakk 78  Caulobacter sp. K31
Q0C2E1           9 DDIAGLMTGALGAARA----A-GEEARTAAQARVRALIADMDLAGRDEVEALKAIATAALDRVDALEARIAALEA 78  Hyphomonas neptuni...
Q0ARN2           9 NDFADLMTDAFGAAQA----M-GEEARTVFRARADRMVAEMDLVTREEFDAVKAALDASQDEVAALTKRLDALEK 78  Maricaulis maris M...
WP_012778169     9 DEAAKFVTGAMGAAQA----A-GDEAKGLLRAQTDRVISEMDLVSREEYDVLKEMFLASQKRVETLEERLQTLEN 78  Hirschia baltica
Q2G4X0           9 ADFVKLLNSAAGTIAG----M-GREAGENAREKAREVFGGLDFVSREEFDAVKDMAAAAREEVEALKARIAALEG 78  Novosphingobium ar...
CCA92888         9 ADFVKMMNSAAGTFAG----M-TREARDTAKERFKELMGDMDFVSREEFDAVKEMAATAREETETLKKQVAALEA 78  Novosphingobium sp...
Q2N979           9 ADFVKLINGAAGTFAG----M-GREARESARERVREAMGGIDFVSREEFDTVKAMAAKARDENEALKKRIEALEA 78  Erythrobacter lito...
WP_007683948     9 DDLAKLVNGAAGTVAG----M-SREFETNAREKAKQWIGGMDFVSRDEFDAVKALAAAAREEVELLKARLDALEG 78  Sphingomonadaceae
WP_014075063     9 DDLSRIINGAAGTVAG----M-TREFEGNARERAREWIGGLDFVSREEFDAVKQMAAEAREQVAQLEARLAALEG 78  Sphingobium sp. SYK-6
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap